704313003: Tofacitinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Janus kinase inhibitor\Tofacitinib (substance)
\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Tofacitinib (substance)

\Drug or medicament (substance)\Immunosuppressant (substance)\Tofacitinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Nitrile (substance)\Tofacitinib (substance)

\Organic compound\Organic nitrogen compound\Nitrile (substance)\Tofacitinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2015. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3012802017 Tofacitinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3012869011 Tofacitinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tofacitinib (substance)	Is a	Immunosuppressant (substance)	true	Inferred relationship	Some
Tofacitinib (substance)	Is a	Anti-rheumatic agent	false	Inferred relationship	Some
Tofacitinib (substance)	Is a	Janus kinase inhibitor	true	Inferred relationship	Some
Tofacitinib (substance)	Has disposition (attribute)	Janus kinase inhibitor (disposition)	true	Inferred relationship	Some
Tofacitinib (substance)	Is a	Chemical categorized functionally	false	Inferred relationship	Some
Tofacitinib (substance)	Has disposition (attribute)	Immunomodulator (disposition)	true	Inferred relationship	Some
Tofacitinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Tofacitinib (substance)	Is a	Nitrile (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Tofacitinib citrate	Is a	False	Tofacitinib (substance)	Inferred relationship	Some
Product containing tofacitinib (medicinal product)	Has active ingredient	True	Tofacitinib (substance)	Inferred relationship	Some	1
Tofacitinib therapy (procedure)	Direct substance	True	Tofacitinib (substance)	Inferred relationship	Some	2
Tofacitinib citrate	Is modification of (attribute)	True	Tofacitinib (substance)	Inferred relationship	Some
Tofacitinib-containing product in oral dose form	Has active ingredient	True	Tofacitinib (substance)	Inferred relationship	Some	1
Product containing only tofacitinib (medicinal product)	Has active ingredient	True	Tofacitinib (substance)	Inferred relationship	Some	1
Tofacitinib only product in oral dose form	Has active ingredient	True	Tofacitinib (substance)	Inferred relationship	Some	1
Product containing precisely tofacitinib (as tofacitinib citrate) 5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tofacitinib (substance)	Inferred relationship	Some	1
Product containing precisely tofacitinib (as tofacitinib citrate) 11 milligram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tofacitinib (substance)	Inferred relationship	Some	1
Tofacitinib (as tofacitinib citrate) 10 mg oral tablet	Has basis of strength substance (attribute)	True	Tofacitinib (substance)	Inferred relationship	Some	1
Tofacitinib (as tofacitinib citrate) 1 mg/mL oral solution	Has basis of strength substance (attribute)	True	Tofacitinib (substance)	Inferred relationship	Some	1

This concept is not in any reference sets