| Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
| Formyltetrahydrofolate deformylase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Inorganic pyrophosphatase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Lysosomal enzyme |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Extended-spectrum beta lactamase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Beta-N-acetylhexosaminidase A |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Beta-N-acetylhexosaminidase B |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Beta-N-acetylhexosaminidase I |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Sulfatase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Thymidine-triphosphatase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Type I site-specific deoxyribonuclease |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Fructan beta-fructosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Pancreatic ribonuclease |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Palmitoyl-coenzyme A hydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Xylan endo-1,3-beta-xylosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Galacturan 1,4-alpha-galacturonidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Glucan endo-1,6-beta-glucosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Mannan 1,4-beta-mannobiosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Cathepsin R |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Renin |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Allantoinase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Kynureninase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Flaviastase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| alpha-Glucosidase (substance) |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Disaccharidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Lipase |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Gamma-cystathionase |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Multiple lysosomal hydrolases |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Fumarase |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Alpha-L-iduronidase |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| 5-oxoprolinase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Inosine triphosphate pyrophosphohydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| S-Adenosyl homocysteine hydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Glycopeptide alpha-N-acetylgalactosaminidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Acylsphingosine deacylase |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Substance with serine protease mechanism of action |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Prorenin |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Elastase |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Bis (5'-guanosyl) tetraphosphatase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Galactosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Deaminase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Hydratase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Mannosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Fucosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Cerebrosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Uridine monophosphate hydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Serratia marcescans nuclease |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Prenyl-pyrophosphatase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Glycerol-1,2-cyclic-phosphate 2-phosphodiesterase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Pentanamidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Lysozyme |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Amidinoaspartase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Pectinesterase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Ficin |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Peptidoglycan beta-N-acetylmuramidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Adenylylsulfatase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Oxyuranus scutellotus prothrombin-activating proteinase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Cyclomaltodextrinase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Adenosine-tetraphosphatase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Adenosine diphosphate sugar pyrophosphatase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Mycodextranase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| 6-aminohexanoate-cyclic-dimer hydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Deoxyribonuclease IV (Phage T>4<-induced) |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Aminoacyl-histidine dipeptidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Cathepsin D |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Deoxylimonate A-ring-lactonase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Glucan 1,3-beta-glucosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Exo-poly-alpha-galacturonosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Ribonuclease T>1< |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Amidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| D-arabinonolactonase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Ribonuclease IV |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Nicotinamide adenine dinucleotide (phosphate) ^+^ nucleosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Asparaginase |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Oxaloacetase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Beta-L-rhamnosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| w-Amidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Cellulose 1,4-beta-cellobiosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Alpha,alpha-phosphotrehalase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Formylmethionine deformylase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Endogalactosaminidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Phosphoribosyl-adenosine monophosphate cyclohydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Urease |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| N-Acetylglucosamine-6-phosphate deacetylase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Aminoacyl-transfer ribonucleic acid hydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Choloylglycine hydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Glucan 1,4-alpha-maltotetraohydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Isopullulanase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Beta-glucosidase |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Endopolyphosphatase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Limonin-D-ring-lactonase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Sinapine esterase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Guanidinobutyrase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Sporotrichum proteinase II |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Cathepsin G |
Is a |
False |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| K-Carrageenase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Phorbol-diester hydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Ribosylpyrimidine nucleosidase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Na^+^/K^+^-transporting adenosine triphosphatase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Dihydrocoumarin hydrolase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|
| Histidine ammonia-lyase |
Is a |
True |
Substance with hydrolase mechanism of action |
Inferred relationship |
Existential restriction modifier |
|