| Inbound Relationships | Type | Active | Source | Characteristic | Refinability | Group | 
| Late congenital syphilitic osteochondropathy | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Late congenital syphilitic osteochondropathy | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 2 | 
| Optic atrophy due to late congenital syphilis | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Syphilitic aortic incompetence | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Regurgitation of pulmonary valve due to late syphilis | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Congenital syphilitic hepatomegaly | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Mulberry molar teeth | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 2 | 
| Dacryoadenitis caused by Treponema pallidum | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Intermediate uveitis caused by Treponema pallidum | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 2 | 
| Intermediate uveitis caused by Treponema pallidum | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Retinitis of left eye caused by Treponema pallidum | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Retinitis of right eye caused by Treponema pallidum | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Iritis of bilateral eyes due to secondary syphilis | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Iritis of bilateral eyes due to secondary syphilis | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 2 | 
| Iritis of right eye due to secondary syphilis | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Iritis of left eye due to secondary syphilis | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Lues maligna | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Lues maligna | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 2 | 
| Otosyphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 2 | 
| [X]Early syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Neurosyphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Other symptomatic late syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Late syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Early congenital syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Other late congenital syphilis, symptomatic | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Late congenital syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Congenital syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Primary syphilis of other sites | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Other secondary syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Otosyphilis | Causative agent | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Other primary syphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Secondary syphilis of skin or mucus membranes NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Syphilitic uveitis unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Secondary syphilitic uveitis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Secondary syphilis of viscera and bone NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other forms of secondary syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Maternal syphilis, unspecified whether during pregnancy or the puerperium | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Maternal syphilis during pregnancy, childbirth or the puerperium NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Encephalitis due to syphilis unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Latent syphilis unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Syphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Syphilitic endocarditis of heart valve NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other specified cardiovascular system syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Neurosyphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other forms of late syphilis with symptoms | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Late symptomatic syphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Late syphilis unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Juvenile neurosyphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Congenital syphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other primary syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other specified neurosyphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other specified neurosyphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other secondary syphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Unspecified secondary syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Latent early syphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Syphilitic endocarditis of unspecified valve | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other specified cardiovascular system syphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Cardiovascular syphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Syphilis of synovium, tendon or bursa NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other specified late syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other and unspecified syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other late congenital syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Other late congenital syphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Unspecified late congenital syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Early congenital syphilis NOS | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| Unspecified juvenile neurosyphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier |  | 
| [X]Syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| [X]Other secondary syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| [X]Neurosyphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| [X]Other symptomatic late syphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| [X]Early syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| [X]Early congenital syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| [X]Other late congenital syphilis, symptomatic | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| [X]Late syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| [X]Late congenital syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| [X]Congenital syphilis, unspecified | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| [X]Primary syphilis of other sites | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Otosyphilis | Causative agent | False | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 | 
| Qualitative result of Treponema pallidum microscopy (observable entity) | Component | True | Treponema pallidum | Inferred relationship | Existential restriction modifier | 1 |