| Inbound Relationships | Type | Active | Source | Characteristic | Refinability | Group | 
| Exploratory burrhole of cranium | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Iridectomy with scleral trephination | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephine sclerectomy with implant | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephine biopsy | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Corneoscleral trephination | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Fistulization of sclera by trephination | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephine sclerectomy | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephination of cranium | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephination | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Frontal sinusotomy with trephine | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Drainage of cranial sinus by trephination | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephine removal of sebaceous cyst | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Exploratory burrhole of cranium | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Bone marrow trephine | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Sternal trephine | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Iliac crest trephine | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Iridectomy with scleral trephination | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Bone marrow trephine biopsy NEC | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephine sclerectomy with implant | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephine biopsy | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Corneoscleral trephination | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Fistulization of sclera by trephination | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephine sclerectomy | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephination of cranium | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephination | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Frontal sinusotomy with trephine | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Drainage of cranial sinus by trephination | Direct device | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephine removal of sebaceous cyst | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Exploratory burrhole of cranium | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Bone marrow trephine | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Sternal trephine | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Iliac crest trephine | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Iridectomy with scleral trephination | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Trephine sclerectomy with implant | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Trephine biopsy | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Corneoscleral trephination | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Fistulization of sclera by trephination | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Trephine sclerectomy | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination of cranium | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Frontal sinusotomy with trephine | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Drainage of cranial sinus by trephination | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 3 | 
| Bone marrow trephine biopsy NEC | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Trephine of cornea | Using | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephine of cornea | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephine removal of sebaceous cyst | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Exploratory burrhole of cranium | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Bone marrow trephine | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Sternal trephine | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Iliac crest trephine | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Iridectomy with scleral trephination | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Trephine sclerectomy with implant | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Trephine biopsy | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Corneoscleral trephination | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Corneoscleral trephination | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Fistulization of sclera by trephination | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Trephine sclerectomy | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination of cranium | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Frontal sinusotomy with trephine | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Drainage of cranial sinus by trephination | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 3 | 
| Bone marrow trephine biopsy NEC | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephine biopsy | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephine removal of sebaceous cyst | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Bone marrow trephine | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephine biopsy | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Exploratory burrhole of cranium | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephine sclerectomy with implant | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Bone marrow trephine biopsy NEC | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephine of cornea | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Iridectomy with scleral trephination | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Trephine sclerectomy | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephine removal of sebaceous cyst | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Frontal sinusotomy with trephine | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination of cranium | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Fistulization of sclera by trephination | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 2 | 
| Drainage of cranial sinus by trephination | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 3 | 
| Trephination of cranium and external drainage of effusion from subdural space | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination of cranium and drainage of chronic hematoma from subdural space | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination of cranium and drainage of empyema of subdural space | Using device | False | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination of cranium and external drainage of effusion from subdural space | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination of cranium and drainage of empyema of subdural space | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Trephination of cranium and drainage of chronic hematoma from subdural space | Using device | True | Trephine, device | Inferred relationship | Existential restriction modifier | 1 | 
| Line-powered craniotomy system handpiece | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Foot-switch, electrical | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Corneal trephine manual instrument | Is a | True | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Line-powered corneal trephine system control unit | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Corneoscleral punch | Is a | True | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Corneal trephine handle | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Cranial hand drill, reusable | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Cranial hand drill, single-use | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Corneal punch set | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Bone trephine | Is a | True | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Corneal trephine, reusable | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Sinus trephine | Is a | True | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Cranial trephine, reusable | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Corneal trephine, single-use | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Cranial trephine, single-use | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Cranial hand drill extension | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  | 
| Corneal trephine system | Is a | False | Trephine, device | Inferred relationship | Existential restriction modifier |  |