| Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
| pT3a: Tumor directly invades adrenal gland or perirenal and/or renal sinus fat but not beyond Gerota's fascia (kidney) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3b: Tumor grossly extends into the renal vein or its segmental (muscle-containing) branches, or vena cava below the diaphragm (kidney) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3c: Tumor grossly extends into vena cava above diaphragm or invades the wall of the vena cava (kidney) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT4: Tumor invades beyond Gerota's fascia (kidney) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN1: Metastasis in a single regional lymph node (kidney) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN2: Metastasis in more than one regional lymph node (kidney) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Ampulla of Vater TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1: Tumor limited to ampulla of Vater or sphincter of Oddi (ampulla of Vater) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2: Tumor invades duodenal wall (ampulla of Vater) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3: Tumor invades pancreas (ampulla of Vater) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT4: Tumor invades peripancreatic soft tissues or other adjacent organs or structures (ampulla of Vater) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Liver TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1: Solitary tumor without vascular invasion (liver, including intrahepatic bile ducts) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2: Solitary tumor with vascular invasion or multiple tumors none more than 5 cm (liver, including intrahepatic bile ducts) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3: Multiple tumors more than 5 cm or tumor involving a major branch of the portal or hepatic vein(s) (liver, including intrahepatic bile ducts) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT4: Tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum (liver, including intrahepatic bile ducts) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Renal tumor limited to kidney macroscopically |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Adrenal gland involved by direct invasion of renal tumor |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Adrenal gland involved by metastasis from renal tumor |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Hyperkeratosis |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
| Extent of stromal invasion by tumor cannot be assessed |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Uterine cervix TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1 (I): Cervical carcinoma confined to uterus (extension to corpus should be disregarded) (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1a (IA): Invasive carcinoma diagnosed only by microscopy. All macroscopically visible lesions (even with superficial invasion) are pT1b/IB (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1a1 (IA1): Measured stromal invasion 3.0 mm or less in depth and 7.0 mm or less in horizontal spread (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1a2 (IA2): Measured stromal invasion more than 3.0 mm and not more than 5.0 mm in depth and 7.0 mm or less horizontal spread (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1b (IB): Clinically visible lesion confined to the cervix or microscopic lesion greater than T1a2/IA2 (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1b1 (IB1): Clinically visible lesion 4.0 cm or less in greatest dimension (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1b2 (IB2): Clinically visible lesion more than 4.0 cm in greatest dimension (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2 (II): Cervical carcinoma invades beyond uterus but not to pelvic wall or to lower third of vagina (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2a (IIA): Tumor without parametrial invasion (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2b (IIB): Tumor with parametrial invasion (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3 (III): Tumor extends to pelvic wall and/or involves lower third of vagina and/or causes hydronephrosis or non-functioning kidney (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3a (IIIA): Tumor involves lower third of vagina, no extension to pelvic wall (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3b (IIIB): Tumor extends to pelvic wall and/or causes hydronephrosis or non-functioning kidney (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT4 (IVA): Tumor invades mucosa of bladder or rectum and/or extends beyond true pelvis (bullous edema is not sufficient evidence to classify a tumor as pT4) (TNM category and FIGO stage) (uterine cervix) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pM1 (IVB): Distant metastasis (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Myometrial invasion by tumor absent |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Myometrial invasion by tumor present |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Corpus uteri TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1 (I): Tumor confined to corpus uteri (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1a (IA): Tumor limited to endometrium (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1b (IB): Tumor invades less than one-half of the myometrium (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1c (IC): Tumor invades one-half or more of the myometrium (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2 (II): Tumor invades cervix but does not extend beyond uterus (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2a (IIA): Tumor limited to the glandular epithelium of the endocervix. There is no evidence of connective tissue stromal invasion (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2b (IIB): Invasion of the stromal connective tissue of the cervix (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3 (III): Local and/or regional spread as specified in pT3a, pT3b, pN1, and FIGO IIIA, IIIB, and IIIC (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3a (IIIA): Tumor involves serosa, AND/OR adnexa (direct extension or metastasis) AND/OR cancer cells in ascites or peritoneal washings (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3b (IIIB): Involvement of vagina (direct extension or metastasis), rectal or bladder wall (without mucosal involvement), or pelvic wall(s) (frozen pelvis) (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT4 (IVA): Tumor invades bladder mucosa and/or bowel mucosa (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN1 (IIIC): Regional lymph node metastasis (TNM category and FIGO stage) (corpus uteri) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Tumor site not applicable |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Lesion size cannot be determined |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Skin melanoma TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pTis: Melanoma in situ (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1: Melanoma 1.0 mm or less in thickness, with or without ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1a: Melanoma 1.0 mm or less in thickness and level II or III, no ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT1b: Melanoma 1.0 mm or less in thickness and level IV or V or with ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2: Melanoma 1.01 to 2.0 mm in thickness, with or without ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2a: Melanoma 1.01 to 2.0 mm in thickness, no ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT2b: Melanoma 1.01 to 2.0 mm in thickness, with ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3: Melanoma 2.01 to 4.0 mm in thickness, with or without ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3a: Melanoma 2.01 to 4.0 mm in thickness, no ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT3b: Melanoma 2.01 to 4.0 mm in thickness, with ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT4: Melanoma greater than 4.0 mm in thickness, with or without ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT4a: Melanoma greater than 4.0 mm in thickness, no ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pT4b: Melanoma greater than 4.0 mm in thickness, with ulceration (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN1: Metastasis in one regional lymph node (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN1a: Clinically occult (microscopic) metastasis (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN1b: Clinically apparent (macroscopic) metastasis (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN2: Metastasis in 2 to 3 regional nodes or intralymphatic regional metastasis without nodal metastasis (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN2a: Clinically occult (microscopic) metastasis (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN2b: Clinically apparent (macroscopic) metastasis (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN2c: Satellite or in-transit metastasis without nodal metastasis (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pN3: Metastasis in four or more regional nodes, or matted metastatic nodes, or in-transit metastasis or satellite(s) with metastasis in regional node(s) (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pM1a: Metastasis to skin, subcutaneous tissues, or distant lymph nodes (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pM1b: Metastasis to lung (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| pM1c: Metastasis to visceral site other than lung or distant metastasis at any site associated with an elevated serum lactic dehydrogenase (melanoma of the skin) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Perineural invasion by tumor indeterminate |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Perineural invasion finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Tumor infiltration by lymphocytes absent |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Tumor infiltration by lymphocytes brisk |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Tumor infiltration by lymphocytes non-brisk |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Specimen involvement by macroscopic tumor present |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Specimen involvement by macroscopic tumor absent |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Specimen involvement by macroscopic tumor indeterminate |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Specimen involvement by matted nodes present |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Specimen involvement by matted nodes absent |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Regression of tumor absent |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Regression involving 75 percent or more of tumor, present |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Regression involving less than 75 percent of tumor, present |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Tumor regression finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
|
| Carcinoma of skin (excluding eyelid, vulva, penis, and melanomas) TNM finding |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
| pT1: Tumor 2 cm or less in greatest dimension (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
| pT1a: Tumor 2 cm or less in greatest dimension, limited to dermis or 2 mm or less in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
| pT1b: Tumor 2 cm or less in greatest dimension, limited to dermis and greater than 2 mm in thickness, but not more than 6 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
| pT1c: Tumor 2 cm or less in greatest dimension, invading the subcutis and/or greater than 6 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
| pT2: Tumor more than 2 cm, but not more than 5 cm, in greatest dimension (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
| pT2a: Tumor more than 2 cm, but not more than 5 cm, in greatest dimension, limited to dermis or greater than 2 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |
| pT2b: Tumor more than 2 cm, but not more than 5 cm, in greatest dimension, limited to dermis and greater than 2 mm in thickness, but not more than 6 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Associated morphology |
False |
Morphologically abnormal structure |
Inferred relationship |
Existential restriction modifier |
1 |