387467008: Ciclosporin (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Substance with enzyme inhibitor mechanism of action\Substance with hydrolase inhibitor mechanism of action\Substance with calcineurin inhibitor mechanism of action\Ciclosporin
\Substance categorized by disposition\Substance with antifungal mechanism of action\Ciclosporin
\Substance categorized by disposition\Substance with immunomodulator mechanism of action\Immunosuppressant\Ciclosporin

\Drug or medicament\Anti-infective agent\Substance with antifungal mechanism of action\Ciclosporin
\Drug or medicament\Immunosuppressant\Ciclosporin

\Substance categorized by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide\Peptide\Cyclic peptide\Ciclosporin

\Organic compound\Organic cyclic compound\Polycyclic compound\Cyclic peptide\Ciclosporin
\Organic compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide\Peptide\Cyclic peptide\Ciclosporin

Status: current, Not sufficiently defined by necessary conditions definition status. Date: 31-Jan 2003. Module: SNOMED CT core module

Descriptions:

Id Description Lang Type Status Case? Module

1481558010 Cyclosporine en Synonym Active Entire term case insensitive SNOMED CT core module

1785292014 Ciclosporin en Synonym Active Entire term case insensitive SNOMED CT core module

3482241019 Ciclosporin (substance) en Fully specified name Active Entire term case insensitive SNOMED CT core module

3482242014 Ciclosporin A en Synonym Active Only initial character case insensitive SNOMED CT core module

3482247015 Cyclosporine A en Synonym Active Only initial character case insensitive SNOMED CT core module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Ciclosporin	Is a	Immunologic agent	false	Inferred relationship	Existential restriction modifier
Ciclosporin	Is a	Immunosuppressant	true	Inferred relationship	Existential restriction modifier
Ciclosporin	Is a	Anti-rheumatic agent	false	Inferred relationship	Existential restriction modifier
Ciclosporin	Is a	Drug analyte	false	Inferred relationship	Existential restriction modifier
Ciclosporin	Is a	Allergen class	false	Inferred relationship	Existential restriction modifier
Ciclosporin	Is a	Ciclosporin and/or ciclosporin derivative	false	Inferred relationship	Existential restriction modifier
Ciclosporin	Is a	Substance with calcineurin inhibitor mechanism of action	true	Inferred relationship	Existential restriction modifier
Ciclosporin	Has disposition	Calcineurin inhibitor	true	Inferred relationship	Existential restriction modifier
Ciclosporin	Is a	Cyclic peptide	true	Inferred relationship	Existential restriction modifier
Ciclosporin	Is a	Drug allergen	false	Inferred relationship	Existential restriction modifier
Ciclosporin	Is a	Chemical categorized functionally	false	Inferred relationship	Existential restriction modifier
Ciclosporin	Has disposition	Immunomodulator	true	Inferred relationship	Existential restriction modifier
Ciclosporin	Is a	Substance with antifungal mechanism of action	true	Inferred relationship	Existential restriction modifier
Ciclosporin	Has disposition	Antifungal	true	Inferred relationship	Existential restriction modifier

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Serum cyclosporin measurement	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	2
Cyclosporin poisoning	Causative agent	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Accidental cyclosporin poisoning	Causative agent	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Intentional cyclosporin poisoning	Causative agent	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporin poisoning of undetermined intent	Causative agent	False	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Cyclosporin adverse reaction	Causative agent	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Allergy to ciclosporin	Causative agent	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporin overdose	Causative agent	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Accidental cyclosporin overdose	Causative agent	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Intentional cyclosporin overdose	Causative agent	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Cyclosporin overdose of undetermined intent	Causative agent	False	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Blood cyclosporin measurement	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	2
Product containing precisely ciclosporin 25 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Product containing precisely ciclosporin 100 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Product containing precisely ciclosporin 50 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Product containing precisely ciclosporin 10 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporin 100mg/mL s/f oral solution	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporin 50mg/1mL oily infusion concentrate	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporin 250mg/5mL oily infusion concentrate	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporine measurement	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Cyclosporine 250mg/amp	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporine 100mg/mL solution	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporine 250mg/5mL	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporine 100mg/5mL solution	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporine 25mg gel	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporine 100mg gel capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporine 50mg gel	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Product containing ciclosporin	Has active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Ciclosporin metabolites	Is a	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporine ophthalmic emulsion 0.05%	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Restasis ophthalmic emulsion 0.05%	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Ciclosporin measurement, polyclonal	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	2
Ciclosporin measurement, monoclonal	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	2
Ciclosporin measurement, high performance liquid chromatography equivalent	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Cyclosporine 50mg gel	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Cyclosporine 250mg/amp	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Accidental cyclosporin poisoning	Causative agent	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Intentional cyclosporin poisoning	Causative agent	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Ciclosporin modified immediate release	Is a	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Product containing ciclosporin in parenteral dose form (medicinal product form)	Has active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing ciclosporin in ophthalmic dosage form	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Product containing ciclosporin in oral dose form (medicinal product form)	Has active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Plasma cyclosporin level	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	2
Measurement of ciclosporin 2 hours after dosing	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Measurement of ciclosporin trough concentration	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Quantitative measurement of mass concentration of ciclosporin in serum or plasma specimen using enzyme immunoassay technique	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	2
Allergy to ciclosporin	Causative agent	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Cyclosporin A poisoning	Causative agent	False	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Nephropathy caused by ciclosporin	Causative agent	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Cyclosporine therapy	Direct substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	2
Product containing precisely ciclosporin 25 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 25 milligram/1 each conventional release oral capsule	Has basis of strength substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 100 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 100 milligram/1 each conventional release oral capsule	Has basis of strength substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 each conventional release oral capsule	Has basis of strength substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 10 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 10 milligram/1 each conventional release oral capsule	Has basis of strength substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Product containing precisely ciclosporin 50 milligram/1 each conventional release oral capsule	Has precise active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 25 milligram/1 each conventional release oral capsule	Has precise active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 100 milligram/1 each conventional release oral capsule	Has precise active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 10 milligram/1 each conventional release oral capsule	Has precise active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 100 milligram/1 milliliter conventional release oral solution	Has basis of strength substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 100 milligram/1 milliliter conventional release oral solution	Has precise active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 milliliter conventional release solution for infusion ampule	Has basis of strength substance	False	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 milliliter conventional release solution for infusion ampule	Has precise active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing ciclosporin in ocular dose form (medicinal product form)	Has active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Ciclosporin	Has active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing only ciclosporin in ocular dose form (medicinal product form)	Has active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing only ciclosporin in oral dose form (medicinal product form)	Has active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing only ciclosporin in parenteral dose form (medicinal product form)	Has active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 milliliter conventional release solution for infusion (clinical drug)	Has basis of strength substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 milliliter conventional release solution for infusion (clinical drug)	Has precise active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has basis of strength substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 500 microgram/1 milliliter conventional release eye suspension (clinical drug)	Has precise active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 500 microgram/1 milliliter conventional release eye suspension (clinical drug)	Has basis of strength substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Cyclosporin index	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Chronic cyclosporin A nephrotoxicity	Causative agent	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 1 milligram/1 milliliter conventional release eye drops (clinical drug)	Has precise active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 1 milligram/1 milliliter conventional release eye drops (clinical drug)	Has basis of strength substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 milliliter conventional release solution for infusion and/or injection (clinical drug)	Has precise active ingredient	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 milliliter conventional release solution for infusion and/or injection (clinical drug)	Has basis of strength substance	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Mass concentration of cyclosporin in plasma (observable entity)	Component	True	Ciclosporin	Inferred relationship	Existential restriction modifier	1
Product containing precisely ciclosporin 50 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Product containing precisely ciclosporin 100 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Product containing precisely ciclosporin 25 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Product containing precisely ciclosporin 10 milligram/1 each conventional release oral capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Ciclosporin 100mg/mL s/f oral solution - product	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Ciclosporin 25mg capsule - product	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Ciclosporin 50mg/1mL oily infusion concentrate - product	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Ciclosporin 100mg capsule - product	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Ciclosporin 250mg/5mL oily infusion concentrate - product	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Ciclosporin 50mg capsule - product	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Ciclosporin 10mg capsule - product	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Sandimmun 250mg/5mL oily infusion concentrate	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Sandimmun 25mg capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Sandimmun 100mg capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Sandimmun 100mg/mL s/f oral solution	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier
Sandimmun 50mg capsule	Has active ingredient	False	Ciclosporin	Inferred relationship	Existential restriction modifier

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Id	Description	Lang	Type	Status	Case?	Module
1481558010	Cyclosporine	en	Synonym	Active	Entire term case insensitive	SNOMED CT core module
1785292014	Ciclosporin	en	Synonym	Active	Entire term case insensitive	SNOMED CT core module
3482241019	Ciclosporin (substance)	en	Fully specified name	Active	Entire term case insensitive	SNOMED CT core module
3482242014	Ciclosporin A	en	Synonym	Active	Only initial character case insensitive	SNOMED CT core module
3482247015	Cyclosporine A	en	Synonym	Active	Only initial character case insensitive	SNOMED CT core module