387152000: Alteplase (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Substance with enzyme activator mechanism of action (substance)\Substance with plasminogen activator mechanism of action\Alteplase
\Substance categorized by disposition\Substance with enzyme mechanism of action\Substance with hydrolase mechanism of action\Protease\Substance with plasminogen activator mechanism of action\Alteplase

\Substance categorized by structure\Chemical\Chemical categorized by structure\...

\Nitrogen and/or nitrogen compound\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide\Polypeptide\Protein\Alteplase

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative\Substituted amide\Polypeptide\Protein\Alteplase

\Biological substance\Polypeptide\Protein\Alteplase

Status: current, Not sufficiently defined by necessary conditions definition status. Date: 31-Jan 2003. Module: SNOMED CT core module

Descriptions:

Id Description Lang Type Status Case? Module

1461330011 Alteplase (substance) en Fully specified name Active Entire term case insensitive SNOMED CT core module

1481260011 Alteplase en Synonym Active Entire term case insensitive SNOMED CT core module

3635509011 Tissue-type plasminogen activator en Synonym Active Entire term case insensitive SNOMED CT core module

3635514010 rt-PA - Tissue-type plasminogen activator en Synonym Active Entire term case sensitive SNOMED CT core module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Alteplase	Is a	Tissue plasminogen activator	false	Inferred relationship	Existential restriction modifier
Alteplase	Is a	Substance with plasminogen activator mechanism of action	false	Inferred relationship	Existential restriction modifier
Alteplase	Has disposition	Plasminogen activator	true	Inferred relationship	Existential restriction modifier
Alteplase	Is a	Substance with plasminogen activator mechanism of action	true	Inferred relationship	Existential restriction modifier
Alteplase	Is a	Substance with hydrolase mechanism of action	false	Inferred relationship	Existential restriction modifier
Alteplase	Is a	Protein	true	Inferred relationship	Existential restriction modifier

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing alteplase	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Alteplase adverse reaction	Causative agent	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Allergy to alteplase	Causative agent	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 50mg powder and solvent for injection solution vial	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 20mg powder and solvent for injection solution vial	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 10mg powder and solvent for injection solution vial	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 100mg powder	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 1mg injection solution 1mL vial	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Continuous infusion of alteplase	Direct substance	False	Alteplase	Inferred relationship	Existential restriction modifier	1
Continuous infusion of alteplase	Direct substance	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Allergy to alteplase	Causative agent	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Product containing precisely alteplase 50 milligram/1 vial powder for conventional release solution for injection	Has basis of strength substance	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Product containing precisely alteplase 50 milligram/1 vial powder for conventional release solution for injection	Has precise active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Product containing precisely alteplase 10 milligram/1 vial powder for conventional release solution for injection	Has precise active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Product containing precisely alteplase 10 milligram/1 vial powder for conventional release solution for injection	Has basis of strength substance	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Product containing precisely alteplase 20 milligram/1 vial powder for conventional release solution for injection	Has basis of strength substance	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Product containing precisely alteplase 20 milligram/1 vial powder for conventional release solution for injection	Has precise active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Product containing alteplase in parenteral dose form (medicinal product form)	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Alteplase	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Product containing only alteplase in parenteral dose form (medicinal product form)	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Product containing precisely alteplase 2 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	Has precise active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Product containing precisely alteplase 2 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	Has basis of strength substance	True	Alteplase	Inferred relationship	Existential restriction modifier	1
Alteplase 20mg injection (pdr for recon)+diluent - product	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 50mg injection (pdr for recon)+diluent - product	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 10mg injection (pdr for recon)+diluent - product	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 20mg injection (pdr for recon)+diluent	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 50mg injection (pdr for recon)+diluent	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 10mg injection (pdr for recon)+diluent	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 10mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd)	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 20mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd)	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 50mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd)	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 10mg powder and solvent for solution for injection vials 1 vial	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 20mg powder and solvent for solution for injection vials 1 vial	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 50mg powder and solvent for solution for injection vials 1 vial	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 10mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd) 1 vial	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 20mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd) 1 vial	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 50mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd) 1 vial	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 10mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd) 1 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 10mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd)	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 10mg powder and solvent for solution for injection vials 1 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 10mg powder and solvent for injection solution vial	Has specific active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 20mg powder and solvent for injection solution vial	Has specific active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 20mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd) 1 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 20mg powder and solvent for solution for injection vials 1 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 20mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd)	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 50mg powder and solvent for injection solution vial	Has specific active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 50mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd)	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse 50mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd) 1 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 50mg powder and solvent for solution for injection vials 1 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg powder and solvent for solution for injection vials	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg powder and solvent for solution for injection vials	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse Cathflo 2mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd)	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse Cathflo 2mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd)	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg powder and solvent for solution for injection vials 5 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse Cathflo 2mg powder and solvent for solution for injection vials (Boehringer Ingelheim Ltd) 5 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg/2ml solution for injection pre-filled syringes	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg/2ml solution for injection pre-filled syringes	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 4mg/4ml solution for injection vials	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 4mg/4ml solution for injection vials	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg/2ml solution for injection pre-filled syringes (Special Order)	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg/2ml solution for injection pre-filled syringes (Special Order)	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 4mg/4ml solution for injection vials (Special Order)	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 4mg/4ml solution for injection vials (Special Order)	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 4mg/4ml solution for injection vials 10 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 4mg/4ml solution for injection vials 1 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg/2ml solution for injection pre-filled syringes 1 pre-filled disposable injection	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg/2ml solution for injection pre-filled syringes (Special Order) 1 pre-filled disposable injection	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 4mg/4ml solution for injection vials (Special Order) 1 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 4mg/4ml solution for injection vials (Special Order) 10 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 25micrograms/0.1ml solution for injection vials	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 25micrograms/0.1ml solution for injection vials	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 25micrograms/0.1ml solution for injection vials (Special Order)	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 25micrograms/0.1ml solution for injection vials (Special Order)	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 25micrograms/0.1ml solution for injection vials 1 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 25micrograms/0.1ml solution for injection vials (Special Order) 1 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg powder for solution for injection vials	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg powder for solution for injection vials	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse Cathflo 2mg powder for solution for injection vials (Boehringer Ingelheim Ltd)	Has active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse Cathflo 2mg powder for solution for injection vials (Boehringer Ingelheim Ltd)	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 2mg powder for solution for injection vials 5 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Actilyse Cathflo 2mg powder for solution for injection vials (Boehringer Ingelheim Ltd) 5 vial	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 50mg powder and solvent for solution for infusion vials	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 20mg powder and solvent for solution for injection vials	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 10mg powder and solvent for solution for injection vials	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 10mg powder and solvent for solution for injection vials	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 10mg powder and solvent for solution for injection vials	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 20mg powder and solvent for solution for injection vials	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 20mg powder and solvent for solution for injection vials	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 50mg powder and solvent for solution for infusion vials	Has active ingredient	False	Alteplase	Inferred relationship	Existential restriction modifier
Alteplase 50mg powder and solvent for solution for infusion vials	Has specific active ingredient	True	Alteplase	Inferred relationship	Existential restriction modifier

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461330011	Alteplase (substance)	en	Fully specified name	Active	Entire term case insensitive	SNOMED CT core module
1481260011	Alteplase	en	Synonym	Active	Entire term case insensitive	SNOMED CT core module
3635509011	Tissue-type plasminogen activator	en	Synonym	Active	Entire term case insensitive	SNOMED CT core module
3635514010	rt-PA - Tissue-type plasminogen activator	en	Synonym	Active	Entire term case sensitive	SNOMED CT core module