386975001: Tacrolimus (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Substance with enzyme inhibitor mechanism of action\Substance with hydrolase inhibitor mechanism of action\Substance with calcineurin inhibitor mechanism of action\Tacrolimus
\Substance categorized by disposition\Substance with immunomodulator mechanism of action\Immunosuppressant\Tacrolimus

\Drug or medicament\Immunosuppressant\Tacrolimus

\Substance categorized by structure\Chemical\Chemical categorized by structure\Organic compound\Lactone\Macrolide\Tacrolimus

Status: current, Not sufficiently defined by necessary conditions definition status. Date: 31-Jan 2003. Module: SNOMED CT core module

Descriptions:

Id Description Lang Type Status Case? Module

1461153017 Tacrolimus (substance) en Fully specified name Active Entire term case insensitive SNOMED CT core module

1481089015 Tacrolimus en Synonym Active Entire term case insensitive SNOMED CT core module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tacrolimus	Is a	Immunosuppressant	true	Inferred relationship	Existential restriction modifier
Tacrolimus	Is a	Allergen class	false	Inferred relationship	Existential restriction modifier
Tacrolimus	Is a	Drug allergen	false	Inferred relationship	Existential restriction modifier
Tacrolimus	Is a	Substance with calcineurin inhibitor mechanism of action	true	Inferred relationship	Existential restriction modifier
Tacrolimus	Is a	Macrolide immunosuppressant	false	Inferred relationship	Existential restriction modifier
Tacrolimus	Has disposition	Calcineurin inhibitor	true	Inferred relationship	Existential restriction modifier
Tacrolimus	Is a	Macrolide	true	Inferred relationship	Existential restriction modifier
Tacrolimus	Is a	Chemical categorized functionally	false	Inferred relationship	Existential restriction modifier
Tacrolimus	Has disposition	Immunomodulator	true	Inferred relationship	Existential restriction modifier

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing tacrolimus	Has active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus 5 milligram/1 each conventional release oral capsule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 5mg/mL infusion concentrate 1mL ampule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus 500 microgram/1 each conventional release oral capsule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 5mg/mL injection	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 0.03% ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus [skin]	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus monohydrate 0.03% ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus monohydrate 0.1% ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing tacrolimus in topical dosage form	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing tacrolimus in oral dose form (medicinal product form)	Has active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing tacrolimus in parenteral dose form (medicinal product form)	Has active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Tacrolimus 5mg/mL injection solution 1mL vial	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 5mg/1mL infusion concentrate	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus (as tacrolimus monohydrate) 300 microgram/1 gram conventional release cutaneous ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus (as tacrolimus monohydrate) 1 milligram/1 gram conventional release cutaneous ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 0.1% ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 5mg/mL infusion concentrate 1mL ampule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 5mg/1mL infusion concentrate	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus (as tacrolimus monohydrate) 300 microgram/1 gram conventional release cutaneous ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus (as tacrolimus monohydrate) 1 milligram/1 gram conventional release cutaneous ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Blood tacrolimus level	Component	True	Tacrolimus	Inferred relationship	Existential restriction modifier	2
Serum tacrolimus measurement	Component	True	Tacrolimus	Inferred relationship	Existential restriction modifier	2
Tacrolimus measurement	Component	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Nephropathy caused by tacrolimus	Causative agent	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Tacrolimus 750microgram modified-release tablet	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 4mg modified-release tablet	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 1mg modified-release tablet	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus therapy	Direct substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	2
Tacrolimus monohydrate	Is a	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 each conventional release oral capsule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 each conventional release oral capsule	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 500 microgram/1 each conventional release oral capsule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 500 microgram/1 each conventional release oral capsule	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Tacrolimus 4mg prolonged-release oral tablet	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 1mg prolonged-release oral tablet	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 750microgram prolonged-release orale tablet	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 each conventional release oral capsule	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 500 microgram/1 each conventional release oral capsule	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus (as tacrolimus monohydrate) 1 milligram/1 gram conventional release cutaneous ointment	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus (as tacrolimus monohydrate) 300 microgram/1 gram conventional release cutaneous ointment	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion ampule	Has precise active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion ampule	Has basis of strength substance	False	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Tacrolimus monohydrate	Is modification of	True	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing tacrolimus in cutaneous dose form (medicinal product form)	Has active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Tacrolimus	Has active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing only tacrolimus in cutaneous dose form (medicinal product form)	Has active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing only tacrolimus in oral dose form (medicinal product form)	Has active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing only tacrolimus in parenteral dose form (medicinal product form)	Has active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 300 microgram/1 gram conventional release cutaneous ointment (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 300 microgram/1 gram conventional release cutaneous ointment (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 1 milligram/1 gram conventional release cutaneous ointment (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 1 milligram/1 gram conventional release cutaneous ointment (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 1 milligram/1 sachet granules for conventional release oral suspension (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 1 milligram/1 sachet granules for conventional release oral suspension (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 200 microgram/1 sachet granules for conventional release oral suspension (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 200 microgram/1 sachet granules for conventional release oral suspension (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 each prolonged-release oral capsule (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 each prolonged-release oral capsule (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 4 milligram/1 each prolonged-release oral tablet (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 4 milligram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 3 milligram/1 each prolonged-release oral capsule (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 3 milligram/1 each prolonged-release oral capsule (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral tablet (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 750 microgram/1 each prolonged-release oral tablet (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 750 microgram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 500 microgram/1 each prolonged-release oral capsule (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 500 microgram/1 each prolonged-release oral capsule (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral capsule (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral capsule (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion and/or injection (clinical drug)	Has precise active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion and/or injection (clinical drug)	Has basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier	1
Measurement of concentration of tacrolimus in whole blood specimen (procedure)	Component	True	Tacrolimus	Inferred relationship	Existential restriction modifier	3
Measurement of concentration of tacrolimus in whole blood specimen (procedure)	Component	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus 5 milligram/1 each conventional release oral capsule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Prograf 1mg capsules (Pilsco Ltd)	Has specific active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier
Prograf 1mg capsules (Pilsco Ltd) 60 capsule	Has specific active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier
Prograf 500microgram capsules (Pilsco Ltd)	Has specific active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier
Prograf 500microgram capsules (Pilsco Ltd) 30 capsule	Has specific active ingredient	True	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus (as tacrolimus monohydrate) 1 milligram/1 gram conventional release cutaneous ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus 500 microgram/1 each conventional release oral capsule	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Protopic 0.03% ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Protopic 0.1% ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Product containing precisely tacrolimus (as tacrolimus monohydrate) 300 microgram/1 gram conventional release cutaneous ointment	Has active ingredient	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus monohydrate	Is a	False	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 0.1% ointment (DE Pharmaceuticals) 60 gram	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 0.1% ointment (DE Pharmaceuticals) 30 gram	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 0.1% ointment (DE Pharmaceuticals)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier
Tacrolimus 2mg modified-release capsules	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier
Dailiport 1mg modified-release capsules (Sandoz Ltd) 50 capsule 5 x 10 capsules	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier
Dailiport 3mg modified-release capsules (Sandoz Ltd)	Has NHS dm+d (dictionary of medicines and devices) basis of strength substance	True	Tacrolimus	Inferred relationship	Existential restriction modifier

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Id	Description	Lang	Type	Status	Case?	Module
1461153017	Tacrolimus (substance)	en	Fully specified name	Active	Entire term case insensitive	SNOMED CT core module
1481089015	Tacrolimus	en	Synonym	Active	Entire term case insensitive	SNOMED CT core module