| Inbound Relationships | Type | Active | Source | Characteristic | Refinability | Group | 
| Distant metastasis present | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| International Federation of Gynecology and Obstetrics uterine tumor stage finding | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| National Wilms Tumor Study Group Stage V | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Very large tumor | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Single lesion | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T4: Breast tumor of any size with direct extension to chest wall or skin | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Localized tumor configuration | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Venous (large vessel)/lymphatic (small vessel) invasion by tumor indeterminate | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tis: Epithelium only (carcinoma in situ, no invasion) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Lymphoma stage IIIse | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Venous (large vessel)/lymphatic (small vessel) tumor invasion finding | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| pTX category | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT2c: Bilateral disease (prostate) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Non-invasive (desmoplastic) ovarian tumor omental implants absent | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Renal tumor invasion into adrenal gland macroscopically | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T4b: Edema (including peau d'orange) or ulceration of the skin of the breast or satellite skin nodules confined to the same breast | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Left regional lymph node metastasis present | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pTis: Intratubular germ cell neoplasia (carcinoma in situ) (testis) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor grade GB | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Skin melanoma TNM finding | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor pigmentation, patchy/focal | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| G4: Undifferentiated (less than 5 percent gland forming) | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T2: Breast tumor > 2 cm but <= 5 cm in greatest dimension | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Breslow measurement - Invasion 0.76 to 1.5mm from deep border of granular layer | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Distance of tumor from anal verge unknown | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor necrosis absent | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| International neuroblastoma staging system stage 1 | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pN1 (IVB): Unilateral regional lymph node metastasis (pT1-pT4, pM1) (TNM category and FIGO stage) (vulva) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Seminal vesicle invasion by tumor present | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| N2: Metastasis in a single ipsilat lymph node >3cm but <6cm in greatest dimension; or in multiple ipsilat lymph nodes, none >6cm in greatest dimension; or in bilat or contralat lymph nodes, none >6cm in greatest dimension | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor stage T2b | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pM1a: Distant metastasis (esophagus) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T2: Urinary bladder tumor invades muscle | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| N1: Metastasis in a single lymph node, < 2 cm in greatest dimension | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Adenocarcinoma of lung, stage III | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T2 (IIA): Trophoblast: gestational trophoblastic tumor involving genital structure without risk factors | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T1a (IA): Tumor limited to one fallopian tube without penetrating the serosal surface, no ascites | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Renal vein uninvolved by renal tumor | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT2c: Tumor invades optic nerve up to, but not through, the level of the lamina cribrosa and invades the choroid focally (retinoblastoma) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor site cannot be determined | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Clinical stage III | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| N1: Metastasis in perirectal lymph node or nodes | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T2: Pleural tumor invades any of the following: ipsilateral lung, endothoracic fascia, diaphragm, or pericardium | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1a: Tumor involves ipsilateral parietal (mediastinal, diaphragmatic) pleura. No involvement of the visceral pleura (thoracic mesothelioma) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Pulmonary parenchymal invasion by tumor cannot be assessed | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Radiographic radiopacity of tooth | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Bilateral lung opacities on chest X-ray | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Clinical stage 0 | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT4b: Tumor directly invades or is adherent to other organs or structures (colon/rectum) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT4a: Tumor penetrates to surface of visceral peritoneum (colon/rectum) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Radiologic infiltrate of lung | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Multilobar lung infiltrate | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Single lobe lung infiltrate | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Multiple nodules of lung | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Multiple hyalinizing granuloma of lung | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Gleason score X | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Gleason grade group 2 | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Gleason grade group 3 | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Gleason grade group 5 | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Gleason grade group 4 | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Gleason grade group 1 | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor surgically resectable | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor pseudoprogression | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor hyperprogression | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor mutational burden | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| High tumor mutational burden | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Low tumor mutational burden | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| International Federation of Gynecology and Obstetrics uterine tumor stage finding | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 1 | 
| International Federation of Gynecology and Obstetrics stage finding for endometrial carcinoma | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 1 | 
| International Federation of Gynecology and Obstetrics stage finding for fallopian tube tumor | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 1 | 
| International Federation of Gynecology and Obstetrics stage finding for vulvar carcinoma | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 1 | 
| International Federation of Gynecology and Obstetrics stage finding for cervical carcinoma | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 1 | 
| International Federation of Gynecology and Obstetrics vulvar melanoma stage V | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 1 | 
| Discharge from skin ulcer | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Cyanosis of skin over lesion | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Temperature of skin over lesion hot | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Temperature of skin over lesion cold | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Temperature of skin over lesion warm | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Shininess of skin over lesion | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Redness of skin over lesion | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Locally advanced malignant neoplasm | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Retroplacental clot volume | Is a | True | Lesion observable | Inferred relationship | Existential restriction modifier |  | 
| Incomplete excision of lesion | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IA | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IIB | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IIIC | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IV M1c | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IIA | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IV M1a | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IIC | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IIIB | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IB | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IV M1b | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IIIA | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Malignant melanoma stage IA | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier |  | 
| Malignant melanoma stage IB | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier |  | 
| Malignant melanoma stage IIA | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier |  | 
| Malignant melanoma stage IIB | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier |  | 
| Malignant melanoma stage IIC | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier |  | 
| Malignant melanoma stage IIIA | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier |  | 
| Malignant melanoma stage IIIB | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier |  |