| Inbound Relationships | Type | Active | Source | Characteristic | Refinability | Group | 
| No pT1 category, insufficient tissue (prostate) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T4: Aerodigestive tract tumor invades adjacent structures (thyroid/cricoid cartilage, carotid artery, soft tissues of neck, prevertebral fascia/muscles, thyroid and/or esophagus) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Lymphoma involves spleen | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| M1b (IVA): All other metastatic sites without risk factors | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT3: Tumor limited to the larynx with vocal cord fixation, and/or invades the paraglottic space, and/or minor thyroid cartilage erosion (larynx, glottis) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Carcinoma of colon, stage II | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| International Federation of Gynecology and Obstetrics endometrial cancer stage IIIC1 | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T1: Clinically inapparent prostate tumor not palpable or visible by imaging | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT3: Tumor more than 4 cm in greatest dimension (oropharynx) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Functional pancreatic endocrine tumor | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1: Tumor invades lamina propria or muscle layer (gallbladder) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Oropharynx TNM finding | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT2: Tumor invades muscularis propria (esophagus) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| International neuroblastoma pathology classification: Unfavorable histology group, patient 5 years or older, with any subtype of neuroblastoma (Schwannian stroma-poor) and any mitosis-karyorrhexis index | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Venous (large vessel)/lymphatic (small vessel) invasion by tumor cannot be assessed | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Pleural invasion by tumor present | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Abnormal radiologic density, unequal | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1: Tumor limited to the subglottis (larynx, subglottis) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T2a (IIA): Fallopian tube tumor with extension and/or metastasis to the uterus and/or ovaries | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| World Health Organization grade I central nervous system tumor | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1a: Tumor 2 cm or less in greatest dimension, limited to dermis or 2 mm or less in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| Tumor progression | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T3a,b: Colon/rectum tumor invades <=5 mm beyond the border of the muscularis propria | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Flat tumor | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| International Federation of Gynecology and Obstetrics cervical cancer (FIGO CC) stage IB2 | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT2: Tumor more than 2 cm but not more than 4 cm in greatest dimension (oropharynx) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Lesion size cannot be determined | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Corpus uteri TNM finding | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT2a (IIA): Tumor limited to the glandular epithelium of the endocervix. There is no evidence of connective tissue stromal invasion (TNM category and FIGO stage) (corpus uteri) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1a2 (IA2): Measured stromal invasion more than 3.0 mm and not more than 5.0 mm in depth and 7.0 mm or less horizontal spread (TNM category and FIGO stage) (uterine cervix) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT4: Tumor invades adjacent organs, or through the kidney into the perinephric fat (renal pelvis and ureter) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| N1b: Metastasis to lymph node(s), any > 0.2 cm in greatest dimension | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Adenocarcinoma of lung, stage II | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pTX: Primary tumor cannot be assessed, or tumor proven by the presence of malignant cells in sputum or bronchial washings but not visualized by imaging or bronchoscopy (lung) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T1: Tumor limited to the antral mucosa with no erosion or destruction of bone | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T3a: Bladder tumor invades perivesical tissue microscopically | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor nodule size cannot be assessed | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pN2b: Clinically apparent (macroscopic) metastasis (melanoma of the skin) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T2a: Stomach tumor invades muscularis propria | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Lymphatic (small vessel) invasion by tumor indeterminate | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Fungating tumor | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T3 and/or N1 (III): Ovarian tumor involves one or both ovaries with microscopically confirmed peritoneal metastasis outside the pelvis and/or regional lymph node metastasis | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Blood/lymphatic vessel invasion by tumor indeterminate (breast) | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| pT1c: Tumor 2 cm or less in greatest dimension, invading the subcutis and/or greater than 6 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| pT1a: Tumor invades lamina propria (stomach) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T1: Tumor invades submucosa (colon/rectum) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T3: Aerodigestive tract tumor > 4 cm in greatest dimension | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1c: Tumor 10 mm or less in greatest diameter and 2.5 mm or less in greatest height (thickness) with macroscopic extraocular extension (ciliary body and choroid) (uveal melanoma) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Node stage N2c | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pN1: Metastasis in 1 to 3 regional lymph nodes (colon/rectum) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Viable tumor present in specimen | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Radiologic opacity | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| International Federation of Gynecology and Obstetrics cervical cancer (FIGO CC) stage IIIB | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Anal canal TNM finding | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Clark melanoma level finding | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor invades beyond pancreatic capsule to colon (endocrine pancreas) | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Extent of stromal invasion by tumor cannot be assessed | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| pT3 (III): Tumor involves one or both fallopian tubes, with peritoneal implants outside the pelvis (TNM category and FIGO stage) (fallopian tube) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Intergroup rhabdomyosarcoma study post-surgical clinical group IA: localized tumor, confined to site of origin, completely resected | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT3 category | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Appendix with tumor involvement, with perforation not at tumor | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| International Federation of Gynecology and Obstetrics vulvar melanoma stage IV | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT3a: Tumor invades optic nerve through the level of the lamina cribrosa but not to the line of resection (retinoblastoma) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T4: Lung tumor of any size that invades any of the following: mediastinum; heart; great vessels; trachea; esophagus; vertebral body; carina | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1b (IB): Clinically visible lesion confined to the cervix or microscopic lesion greater than T1a2/IA2 (TNM category and FIGO stage) (uterine cervix) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T4: Urinary bladder tumor invades any of the following: prostate, uterus, vagina, pelvic wall abdominal wall | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pTis: Carcinoma in situ, intraepithelial (colon/rectum) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Functional status of pancreatic endocrine tumor unknown | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Node stage N1biv | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pN1a: Metastasis to level VI (pretracheal, paratracheal, and prelaryngeal/Delphian lymph nodes) (thyroid) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pM1a: Metastasis to skin, subcutaneous tissues, or distant lymph nodes (melanoma of the skin) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T3c,d: Colon/rectum tumor invades >5 mm beyond the border of the muscularis propria | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT2c category | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pN1b: Metastasis to unilateral, bilateral, or contralateral cervical or superior mediastinal lymph nodes (thyroid) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT3 (III): Tumor extends to pelvic wall and/or involves lower third of vagina and/or causes hydronephrosis or non-functioning kidney (TNM category and FIGO stage) (uterine cervix) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1b (IB): Tumor invades less than one-half of the myometrium (TNM category and FIGO stage) (corpus uteri) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| N2: Metastasis in more than one regional lymph node | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| M1b (IV): All other metastatic sites | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT4b: Extrathyroidal anaplastic carcinoma - surgically unresectable (anaplastic carcinoma) (thyroid) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Lymphoma finding | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Lymphoma stage III | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Tumor involvement of noncontiguous structures absent | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1a: Tumor limited to one vocal cord (may involve anterior or posterior commissure) with normal mobility (larynx, glottis) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Primitive neuroectodermal tumor/Ewing's sarcoma TNM finding | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Low grade lymphoma, stage 1 | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1: Tumor limited to the testis and epididymis without vascular/lymphatic invasion; tumor may invade into the tunica albuginea but not the tunica vaginalis (testis) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1b (IB): Tumor confined to the vulva or vulva and perineum, 2 cm or less in greatest dimension, and with stromal invasion greater than 1 mm (TNM category and FIGO stage) (vulva) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT2a: Tumor confluent with or extending into the ciliary body and/or choroid with melanomalytic glaucoma (iris) (uveal melanoma) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Regional lymph nodes cannot be assessed | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pN2a category | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pN0(mol-) category | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| N3a: > 6 cm in dimension | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT4a: Tumor directly invades other organs or structures (colon/rectum) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier |  | 
| pT2: Tumor invades muscularis propria (colon/rectum) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Microcalcifications in non-neoplastic tissue present | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Invasive tumor border | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 3 | 
| T3a: Renal tumor invades the adrenal gland or perinephric tissues but not beyond Gerota's fascia | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Epithelial ovarian tumor, International Federation of Gynecology and Obstetrics stage IC | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| pT1: Tumor invades lamina propria or submucosa (stomach) | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| T1a: Esophagus/stomach tumor invades lamina propria | Interprets | False | Lesion observable | Inferred relationship | Existential restriction modifier | 2 | 
| Status of metastases in marker lymph node unknown | Interprets | True | Lesion observable | Inferred relationship | Existential restriction modifier | 2 |