| Inbound Relationships | 
Type | 
Active | 
Source | 
Characteristic | 
Refinability | 
Group | 
| Hyperkeratotic eczema of palms and soles | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 5 | 
| Progressive palmoplantar keratoderma of Greither | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Progressive palmoplantar keratoderma of Greither | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 4 | 
| Progressive palmoplantar keratoderma of Greither | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 5 | 
| Palmoplantar keratoderma transgrediens | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Palmoplantar keratoderma transgrediens | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 4 | 
| Acroerythrokeratoderma | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Acroerythrokeratoderma | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 4 | 
| Autosomal recessive epidermolytic ichthyosis | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Hyperkeratosis of vulva | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Congenital palmoplantar and perioral keratoderma of Olmsted | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Pachyonychia congenita syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Pachyonychia congenita syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 4 | 
| Pachyonychia congenita type II of Jackson-Lawler | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Pachyonychia congenita type II of Jackson-Lawler | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 4 | 
| Pachyonychia congenita type III of Schafer-Brunauer | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Pachyonychia congenita type III of Schafer-Brunauer | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 4 | 
| Generalized peeling skin syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Hereditary skin peeling syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Acral peeling skin syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Aquagenic palmoplantar keratoderma | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Aquagenic palmoplantar keratoderma | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Knuckle pads, leukonychia, sensorineural deafness, palmoplantar hyperkeratosis syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 6 | 
| Knuckle pads, leukonychia, sensorineural deafness, palmoplantar hyperkeratosis syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 8 | 
| Hyperkeratosis of female perineum | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Congenital ichthyosis, microcephalus, tetraplegia syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Congenital ichthyosis, intellectual disability, spastic quadriplegia syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Hypohidrosis, electrolyte imbalance, lacrimal gland dysfunction, ichthyosis, xerostomia syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Keratin 1-related diffuse nonepidermolytic palmoplantar keratoderma | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Keratin 1-related diffuse nonepidermolytic palmoplantar keratoderma | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Palmoplantar keratoderma, hereditary motor and sensory neuropathy syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Palmoplantar keratoderma, hereditary motor and sensory neuropathy syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Pigmentation defects, palmoplantar keratoderma, skin carcinoma syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Pigmentation defects, palmoplantar keratoderma, skin carcinoma syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Punctate acrokeratoderma freckle-like pigmentation | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Punctate acrokeratoderma freckle-like pigmentation | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Hyperkeratosis of forefoot | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Generalized inflammatory peeling skin syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Generalized non-inflammatory peeling skin syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Hyperkeratosis of hindfoot | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Ichthyosis hystrix gravior | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Acquired ichthyosis due to paraneoplastic syndrome | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Drug-induced ichthyosiform reaction | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Hyperkeratosis of skin caused by high temperature | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Talar callosity | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Radiation keratosis following radiotherapy | 
Associated morphology | 
True | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Acquired keratoderma NOS | 
Associated morphology | 
False | 
Hyperkeratosis | 
Inferred relationship | 
Existential restriction modifier | 
 1 |