| Inbound Relationships | 
Type | 
Active | 
Source | 
Characteristic | 
Refinability | 
Group | 
| Rectum, unknown surgical margin, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical deep margin uninvolved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Rectum, deep surgical margin, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Tumor invades retina | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Tumor massively invades choroid | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Anal, deep radial surgical margin involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Seminal vesicle invasion by tumor absent | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Surgical exocervical margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical mucosal margin uninvolved by in situ carcinoma | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Tumor invades optic disc | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Increased turbidity | 
Interprets | 
False | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
  | 
| Rectum, left lateral surgical margin, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical exocervical margin finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical mucosal margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Peritumoral lymphocytic response finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical pancreatic parenchymal margin involved by in situ carcinoma | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Gross pathology | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical distal margin involved by in situ carcinoma/adenoma | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Lymphoma involves muscular wall AND/OR subserosa | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Satisfactory for evaluation but limited by lack of pertinent clinical patient information | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical margin involvement by tumor not applicable | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical uncinate process margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical parenchymal margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical deep margin is closest uninvolved margin to malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Rectum, right lateral surgical margin, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Undifferentiated histological grade finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Surgical exocervical margin involved by intraepithelial neoplasia | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical exocervical margin uninvolved by intraepithelial neoplasia | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical proximal pancreatic margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Low grade lymphoma, stage 1 | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Cloudy urine | 
Interprets | 
False | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
  | 
| Surgical margin involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical inferior margin is closest uninvolved margin to malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Tumor invasion of perineural tissue present (prostate) | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Nottingham Combined Grade finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical deep margin involved by intraepithelial neoplasia | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Pancreatic surgical margin, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical vascular margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Distance of tumor from anal verge unknown | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Surgical margin finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Specimen less than optimal for diagnosis | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Proximal pancreatic surgical margin, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical posterior retroperitoneal pancreatic margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Rectum, inferior lateral surgical margin, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Pulmonary parenchymal invasion by tumor cannot be assessed | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| No obvious clot in sample | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Moderately differentiated histological grade finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Surgical deep margin involvement by melanoma cannot be assessed | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical distal pancreatic margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical distal mucosal margin involved by in situ carcinoma | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical bronchial margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical exocervical margin involved by malignant neoplasm, focal | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical deep margin uninvolved by intraepithelial neoplasia | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Venous (large vessel)/lymphatic (small vessel) tumor invasion finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Surgical chest wall margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| G4: Nuclei bizarre and multilobated, 20 µ or greater, nucleoli prominent, chromatin clumped | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical parietal pleural margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Finding of histologic grading differentiation AND/OR behavior | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Histological grade finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Rectum, deep surgical margin, focal, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Anal, distal surgical margin not involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical mesenteric margin uninvolved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical lateral margin is closest uninvolved margin to malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Satisfactory for evaluation but limited by absence of an endocervical/transformation zone component from a patient with a cervix | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Tumor invasion of perineural tissue absent (prostate) | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Surgical bronchial margin involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Integrity of specimen unknown | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical mesenteric margin involved by malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical deep margin finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical exocervical margin involved by malignant neoplasm, diffuse | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Tumor invades mediastinum | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Anal, proximal surgical margin not involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| G3: Nuclei very irregular, approximately 20 µ; nucleoli large and prominent | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Deep surgical margin, focal, involvement by tumor present | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Tissue specimen intact | 
Interprets | 
False | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
  | 
| Unsatisfactory for evaluation due to thick areas | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Local tumor invasion | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Specimen satisfactory for evaluation | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Grade not determined | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Tumor invades epithelium only | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Surgical margin involvement by tumor cannot be assessed | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Breslow measurement - depth greater than 1.75 mm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Nuclear pleomorphism finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Integrity of specimen not specified | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Distal pancreatic surgical margin, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Poorly differentiated histological grade finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 2 | 
| Surgical margin involved by intraepithelial neoplasia | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Vascular invasion by tumor present | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical bronchial margin involved by squamous cell carcinoma in situ | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Tumor invasion deeper than skin | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Anal, proximal surgical margin involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Stomach, distal surgical margin, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Inferior lateral surgical margin involvement by tumor present | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical proximal mucosal margin uninvolved by in situ carcinoma | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Tumor invades sclera | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 3 | 
| Right ovary not present in specimen | 
Interprets | 
False | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
  | 
| Stomach, proximal surgical margin, involved by tumor | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Tissue lost in processing | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical distal margin finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Surgical omental margin is closest uninvolved margin to malignant neoplasm | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 | 
| Breast tubule formation finding | 
Interprets | 
True | 
Histopathology test | 
Inferred relationship | 
Existential restriction modifier | 
 1 |