| Outbound Relationships | Type | Target | Active | Characteristic | Refinability | Group | Values | 
| Combined drug dependence, excluding opioids | Is a | Psychoactive substance dependence | false | Inferred relationship | Existential restriction modifier |  |  | 
| Combined drug dependence, excluding opioids | Causative agent | Psychoactive substance of abuse - non-pharmaceutical | false | Inferred relationship | Existential restriction modifier |  |  | 
| Combined drug dependence, excluding opioids | Causative agent | Drug excluding opioids | false | Inferred relationship | Existential restriction modifier |  |  | 
| Combined drug dependence, excluding opioids | Causative agent | Drug, medicament or biological substance | false | Inferred relationship | Existential restriction modifier |  |  | 
| Combined drug dependence, excluding opioids | Is a | Drug dependence | false | Inferred relationship | Existential restriction modifier |  |  | 
| Combined drug dependence, excluding opioids | Causative agent | Psychoactive substance | false | Inferred relationship | Existential restriction modifier |  |  | 
| Combined drug dependence, excluding opioids | Is a | Combined drug dependence, continuous | false | Inferred relationship | Existential restriction modifier |  |  | 
| Combined drug dependence, excluding opioids | Associated with | Drug or medicament | false | Inferred relationship | Existential restriction modifier | 1 |  | 
| Combined drug dependence, excluding opioids | Causative agent | Drug or medicament | false | Inferred relationship | Existential restriction modifier | 1 |  | 
| Inbound Relationships | Type | Active | Source | Characteristic | Refinability | Group | 
| Combined drug dependence, excluding opioid, continuous | Is a | False | Combined drug dependence, excluding opioids | Inferred relationship | Existential restriction modifier |  | 
| Combined drug dependence, excluding opioid, episodic | Is a | False | Combined drug dependence, excluding opioids | Inferred relationship | Existential restriction modifier |  | 
| Combined drug dependence, excluding opioid, in remission | Is a | False | Combined drug dependence, excluding opioids | Inferred relationship | Existential restriction modifier |  | 
| Combined drug dependence, excluding opioid, unspecified | Is a | False | Combined drug dependence, excluding opioids | Inferred relationship | Existential restriction modifier |  | 
| Combined drug dependence, excluding opioid, NOS | Is a | False | Combined drug dependence, excluding opioids | Inferred relationship | Existential restriction modifier |  | 
| Combined drug dependence, excluding opioid, unspecified | Is a | False | Combined drug dependence, excluding opioids | Inferred relationship | Existential restriction modifier |  | 
| Combined drug dependence, excluding opioid, NOS | Is a | False | Combined drug dependence, excluding opioids | Inferred relationship | Existential restriction modifier |  |