Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
pN1mi(i+): Micrometastasis detected only by immunohistochemistry (breast) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Solid, entirely encapsulated tumor (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
T3: Aerodigestive tract tumor extends to anterior orbit and/or maxillary sinus |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tis: Tumor invades lamina propria (gastrointestinal tumor) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pN0(i-) category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pN0(mol-): No regional lymph node metastasis histologically, negative nonmorphologic (molecular) findings for isolated tumor cells (breast) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pN2a: Metastasis in 4 to 9 axillary lymph nodes (at least one tumor deposit greater than 2.0 mm) (breast) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT1b: Tumor invades muscle layer (gallbladder) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT4: Tumor invades peripancreatic soft tissues or other adjacent organs or structures (ampulla of Vater) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T1b (IB): Endometrial tumor invades up to or less than one half of the endometrium |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T1 (I): Trophoblastic disease confined to uterus |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Thoracic mesothelioma TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pN2b: Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension (upper aerodigestive tract) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Clinical stage IV C |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T4: Tumor invades through thyroid cartilage and/or extends to other tissues beyond the larynx (trachea, soft tissues of neck, pharynx) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumor of moderate extent (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Intergroup rhabdomyosarcoma study post-surgical clinical group IV: Any size primary tumor, with or without regional lymph node involvement, with distant metastases, without respect to surgical approach to primary tumor (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT1b: Tumor more than 0.5 cm but not more than 1 cm in greatest dimension (breast) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumor pigmentation, diffuse (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT2a (IIA): Tumor involves one or both fallopian tubes with extension and/or metastasis to the uterus and/or ovaries (TNM category and FIGO stage) (fallopian tube) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T3: Ureteral tumor invades beyond muscularis into periureteric fat |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T1 (IA): Trophoblastic disease confined to uterus with no risk factors |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT2b (IIB): Tumor involves one or both fallopian tubes with extension to other pelvic structures (TNM category and FIGO stage) (fallopian tube) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumor invasion cannot be assessed |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
pT2b: Tumor more than 2 cm, but not more than 5 cm, in greatest dimension, limited to dermis and greater than 2 mm in thickness, but not more than 6 mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
3 |
pT3a (IIIA): Tumor involves lower third of vagina, no extension to pelvic wall (TNM category and FIGO stage) (uterine cervix) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumor invades optic nerve posterior to lamina cribrosa but not to end of nerve (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Mixed endophytic and exophytic tumor configuration (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Peritoneal tumor implant present (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
No regional lymph node metastasis (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Tunica vaginalis involved by direct extension of malignant neoplasm (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumor stage T3c |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pN1 (III): Pelvic or inguinal lymph node metastasis (pT1-pT3) (TNM category and FIGO stage) (vagina) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
International Federation of Gynecology and Obstetrics cervical cancer (FIGO CC) stage IIA2 |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumor invades dermis (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
Regional lymph node metastasis present (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3b (IIIB): Tumor involves one or both fallopian tubes, with macroscopic peritoneal metastasis outside the pelvis 2 cm or less in greatest dimension (TNM category and FIGO stage) (fallopian tube) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT1b: Tumor involves both vocal cords (may involve anterior or posterior commissure) with normal mobility (larynx, glottis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
International Federation of Gynecology and Obstetrics cervical cancer (FIGO CC) stage IA2 |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Intergroup rhabdomyosarcoma study post-surgical clinical group finding (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
T4a: Bladder tumor invades prostate or uterus or vagina |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT4b: Tumor invades pelvic wall or abdominal wall (urinary bladder) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Atelectasis AND/OR obstructive pneumonitis of entire lung associated with direct extension of malignant neoplasm (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
FIGO stage finding for gynaecological malignancy |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT2a: Tumor invades optic nerve up to, but not through, the level of the lamina cribrosa (retinoblastoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT1b category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3c: Tumor invades the optic nerve through the level of the lamina cribrosa but not to the line of resection and massively invades the choroid (retinoblastoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T1: Tumor limited to ampulla of Vater or sphincter of Oddi |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Distance of adenoma from anal verge unknown (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
Tumor invasion into bronchus, invasive |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Cystic, entirely encapsulated tumor (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
T3: Pleural tumor invades any of the following: ipsilateral chest wall muscle, ribs, or media-stinal organs or tissues |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T2 (II): Vaginal tumor invades paravaginal tissues but not to pelvic wall |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3c and/or N1 (IIIC): Tumor involves one or both fallopian tubes, with peritoneal metastasis outside the pelvis more than 2 cm in diameter AND/OR regional lymph node metastasis (TNM category and FIGO stage) (fallopian tube) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT4b: Tumor involves masticator space, pterygoid plates, or skull base and/or encases internal carotid artery (lip and oral cavity) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumor invasion of perineural tissue absent (prostate) (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
Gleason grade score 8 out of 10 (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Carcinoma of ovary, stage 4 |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
N1a: Only micrometastasis, none > 0.2 cm in greatest dimension |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3 (III): Local and/or regional spread as specified in pT3a, pT3b, pN1, and FIGO IIIA, IIIB, and IIIC (TNM category and FIGO stage) (corpus uteri) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T3: Prostate tumor extends through the prostatic capsule |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pN3 category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Clinical stage II C |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT4 category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Distant metastasis cannot be assessed (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT4: Tumor with extraocular extension (iris) (uveal melanoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
N1: Metastasis with a lymph node mass less than 2 cm in greatest dimension and 5 or fewer positive nodes, none larger than 2 cm in greatest dimension |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Intergroup rhabdomyosarcoma study post-surgical clinical group IIB: Locally extensive tumor (spread to regional lymph nodes), completely resected (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3: Tumor invades through the muscularis propria into the subserosa or into mesoappendix (appendix) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Specimen involvement by macroscopic tumor indeterminate (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pN2b category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Size of base of tumor on transillumination cannot be determined (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pN2: Metastasis with a lymph node mass more than 2 cm but not more than 5 cm in greatest dimension; or more than 5 nodes positive, none more than 5 cm; or evidence of extranodal extension of tumor (testis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Mediastinal pleura involved by direct extension of malignant neoplasm (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumour invasion confined to mucosa and submucosa |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT1c (IC): Tumor limited to one or both ovaries with any of the following: capsule ruptured, tumor on ovarian surface, malignant cells in ascites or peritoneal washings (TNM category and FIGO stage) (ovary) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T3: Aerodigestive tract tumor having extraparenchymal extension without seventh nerve involvement, and/or > 4 cm but < 6 cm in greatest dimension |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pN2c: Satellite or in-transit metastasis without nodal metastasis (melanoma of the skin) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Intermediate grade histologic differentiation (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
T1a2 (IA2): Tumor of uterine cervix with stromal invasion > 3.0 mm but < 5.0 mm in depth and horizontal spread < 7.0 mm |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Clinical stage I S |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Mucinous adenocarcinoma cells present, comprising less than 50 percent of malignant cells (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pN1b: Metastasis in multiple regional lymph node(s) (exocrine pancreas) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Histologic features of tumor cannot be determined (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Parietal pericardium involved by direct extension of malignant neoplasm (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Extraprostatic extension of tumor indeterminate (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Retinoblastoma TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Intraductal tumor configuration |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pM1 (IVB): Distant metastasis (TNM category and FIGO stage) (corpus uteri) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumor invades beyond pancreatic capsule to adjacent structures AND/OR organs (endocrine pancreas) (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
T4d: Inflammatory carcinoma of breast with involvement of skin and chest wall by carcinoma |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T1a (IA): Tumor limited to one ovary, capsule intact, no tumor on ovarian surface |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT1a: Melanoma 1.0 mm or less in thickness and level II or III, no ulceration (melanoma of the skin) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T3 and/or N1 (III): Fallopian tube tumor involves one or both tube(s) with peritoneal implants outside the pelvis and/or regional lymph node metastasis |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT1: Tumor limited to the iris (iris) (uveal melanoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3a (IIIA): Tumor involves one or both fallopian tubes, with microscopic peritoneal metastasis outside the pelvis (TNM category and FIGO stage) (fallopian tube) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Density above reference range (finding) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
3 |
T4: Tumor directly invades adjacent structures |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumor invades retroperitoneal structure (finding) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
T2: Aerodigestive tract tumor > 2 cm but < 4 cm in greatest dimension |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T1a: Tumor limited to one vocal cord |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |