FHIR © HL7.org  |  Server Home  |  FHIR Server FHIR Server 3.9.1  |  FHIR Version n/a  User: [n/a]

768946000: Stevens-Johnson syndrome, toxic epidermal necrolysis spectrum (disorder)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module
3687603019 An acute and severe skin disease with clinical and histological features of destruction and detachment of the skin epithelium and mucous membranes. Onset may occur at any age, but the risk increases after 40 years. Three subforms have been described according to the percentage of the body surface area affected: Stevens-Johnson syndrome (less than 10%), Lyell syndrome (greater than 30%) and an intermediate form (10-29%). The initial manifestations are nonspecific: a seemingly banal rash, fever, and a burning sensation involving the eyes, mouth and genitalia. The rash rapidly progresses to become vesicular and bullous on the face and body. High fever is a constant feature. Two thirds of cases are triggered by a drug allergy. In rare cases, the disease is associated with infections or bone marrow transplantation. The remaining 25-30% of cases are classed as idiopathic. The prognosis for patients with extensive forms is poor. en Definition Inactive Entire term case sensitive (core metadata concept) SNOMED CT core
5404764015 A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. en Definition Active Entire term case sensitive (core metadata concept) SNOMED CT core
5404765019 A rare toxic dermatosis with clinical and histological features characterised by the destruction and detachment of the skin epithelium and mucous membranes. en Definition Active Entire term case sensitive (core metadata concept) SNOMED CT core
3687582015 Stevens-Johnson syndrome, toxic epidermal necrolysis spectrum (disorder) en Fully specified name Active Entire term case sensitive (core metadata concept) SNOMED CT core
3687583013 Stevens-Johnson syndrome, toxic epidermal necrolysis spectrum en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core
3687587014 Toxic epidermolysis en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

9 descendants. Search Descendants:

Expanded Value Set

Outbound Relationships Type Target Active Characteristic Refinability Group Values
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Finding site Skin structure true Inferred relationship Some 2
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Clinical course Sudden onset AND/OR short duration (qualifier value) true Inferred relationship Some 4
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Is a Skin necrosis true Inferred relationship Some
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Is a Acute skin disorder false Inferred relationship Some
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Is a Acute erythematous eruption of skin true Inferred relationship Some
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Is a Erytematøs tilstand false Inferred relationship Some
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Associated morphology Necrosis true Inferred relationship Some 2
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Associated morphology Erythema true Inferred relationship Some 1
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Finding site Skin structure true Inferred relationship Some 1
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Associated morphology Separation true Inferred relationship Some 3
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Finding site Structure of skin and/or mucous membrane (body structure) true Inferred relationship Some 3
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Is a Acute eruption of skin (disorder) false Inferred relationship Some
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Is a Erythroderma (disorder) false Inferred relationship Some
Inbound Relationships Type Active Source Characteristic Refinability Group
An extended form of toxic epidermal necrolysis with characteristics of destruction and detachment of the skin epithelium and mucous membranes involving more than 30% of the body surface area. Lyell syndrome can be triggered by a drug allergy and, exceptionally, by infections or bone marrow transplantation. In 25 to 30% of cases, the cause is unclear. Patients should be admitted to an intensive care or burns unit as soon as the diagnosis is suspected. Prognosis is poor (mortality rate: 20-25%). Is a True A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Inferred relationship Some
Severe mucocutaneous reactions; skin detachment of 10 to 30 percent of body surface area most commonly triggered by medications, characterised by extensive necrosis and detachment of the epidermis. Is a True A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Inferred relationship Some
Stevens-Johnson syndrome is a limited form of toxic epidermal necrolysis with characteristics of destruction and detachment of the skin epithelium and mucous membranes involving less than 10% of the body surface area. The disease can be triggered by a drug allergy and, more rarely, by infections or bone marrow transplantation. In 25 to 30% of cases, the cause is unclear. Is a True A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. Inferred relationship Some

Reference Sets

Component annotation with string value reference set (foundation metadata concept)

Back to Start