| Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
| interferon beta-1b 100 µg injektionsvæske, opløsning |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferon beta-1a 30mcg/vial injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 5 MIE/pulver, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 25 MIE/pulver, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 50 MIE/pulver, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 10 MIE/hætteglas pulver |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 3 MIE/pulver, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 18 MIE/pulver, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 25 MIE/opløsning, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 18 MIE/opløsning, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferon alfa-2b 10 million iu/vial solution |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 3 MIE/opløsning, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 5 MIE/opløsning, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| injicerbart interferon |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Product containing peginterferon alfa-2a (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-n3 humant leu 5 MIE/ml injektionsvæske, opløsning, hætteglas a 1 ml |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2a 6 MIE/injektionsvæske, opløsning, hætteglas a 1 ml |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2a 9 MIE/injektionsvæske, opløsning, hætteglas a 0,9 ml |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2a 36 MIE/ml injektionsvæske, opløsning, hætteglas a 1 ml |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2a 3 MIE/injektionsvæske, opløsning, hætteglas a 1 ml |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2a 18 MIE/3 ml injektionsvæske, opløsning, hætteglas a 3 ml |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2a 3 MIE/injektionsvæske, opløsning, fyldt sprøjte a 0,5 ml |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon beta-1a 30 µg injektionsvæske, opløsning, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferon alfa-2a 6miu/vial injection solution 0.5mL syringe |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| PEG-intron redipen |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| PEG-intron redipen 150 µg pulver + 0,5 ml sterilt vand |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| PEG-intron redipen 120 µg pulver + 0,5 ml sterilt vand |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| PEG-intron redipen 50 µg pulver + 0,5 ml sterilt vand |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| PEG-intron redipen 80 µg pulver + 0,5 ml sterilt vand |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2b 10 MIE/2 ml injektionsvæske, opløsning |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| peginterferon alfa-2b 150 µg pulver + solvens til injektionsvæske, opløsning, fyldt pen |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| peginterferon alfa-2b 50 µg pulver + solvens til injektionsvæske, opløsning, fyldt pen |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| peginterferon alfa-2b 80 µg pulver + solvens til injektionsvæske, opløsning, fyldt pen |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| peginterferon alfa-2b 100 µg pulver + solvens til injektionsvæske, opløsning, fyldt pen |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| peginterferon alfa-2b 120 µg pulver + solvens til injektionsvæske, opløsning, fyldt pen |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| peginterferon alfa-2a 180 µg/0,5 ml injektionsvæske, opløsning i fyldt injektionssprøjte |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| peginterferon alfa-2a 135 µg/0,5 ml injektionsvæske, opløsning i fyldt injektionssprøjte |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon alfa-2a 18 MIE/0,5 ml injektionsvæske, opløsning i fyldt injektionssprøjte |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferons 1million iu injection (pdr for recon) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferons 4.5million iu injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferons 5million units injection (pdr for recon) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferons 10million iu injection (pdr for recon) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferons 30million iu injection (pdr for recon) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferons 3million iu injection (pdr for recon) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferons 9million iu injection (pdr for recon) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferons 18million iu injection (pdr for recon) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferons 3million iu/1mL solution for injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Interferons 10million iu/1mL solution for injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| peginterferon alfa-2a 180 µg/ml injektionsvæske, hætteglas a 1 ml |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| ribavirin + interferon alfa-2b |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| ribavirion 200 mg kapsel + interferon alfa-2b 3 MIE/injektionsvæske, opløsning, hætteglas |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| interferon beta-1b 0,3 mg pulver til injektionsvæske + diluent |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Cytokine |
Inferred relationship |
Some |
|
| Angiogenin (substance) |
Is a |
True |
Cytokine |
Inferred relationship |
Some |
|
| Platelet factor 4 |
Is a |
True |
Cytokine |
Inferred relationship |
Some |
|
| Interleukin |
Is a |
True |
Cytokine |
Inferred relationship |
Some |
|
| Interferon |
Is a |
False |
Cytokine |
Inferred relationship |
Some |
|
| Cytokine agent (substance) |
Is a |
True |
Cytokine |
Inferred relationship |
Some |
|
| Lactoferrin (substance) |
Is a |
True |
Cytokine |
Inferred relationship |
Some |
|
| Platelet-derived growth factor |
Is a |
True |
Cytokine |
Inferred relationship |
Some |
|
| Tumor necrosis factor alpha |
Is a |
False |
Cytokine |
Inferred relationship |
Some |
|
| Tumor necrosis factor beta |
Is a |
False |
Cytokine |
Inferred relationship |
Some |
|
| Lymphotoxin |
Is a |
False |
Cytokine |
Inferred relationship |
Some |
|
| Tumour necrosis factor |
Is a |
True |
Cytokine |
Inferred relationship |
Some |
|
| Ancestim (substance) |
Is a |
True |
Cytokine |
Inferred relationship |
Some |
|
| Transforming growth factor beta 1 |
Is a |
True |
Cytokine |
Inferred relationship |
Some |
|
| Cytokine-associated toxicity (disorder) |
Causative agent |
True |
Cytokine |
Inferred relationship |
Some |
1 |
| A rare systemic condition affecting patients undergoing chimeric antigen receptor (CAR) T-cell therapy and characterized by a systemic inflammatory response due to massive activation of leukocytes with subsequent cytokine release. It can present with a variety of signs and symptoms ranging from mild, flu-like symptoms (such as fever, fatigue, headache, rash, arthralgia, and myalgia) to severe life-threatening manifestations including vascular leakage, disseminated intravascular coagulation, shock, and multiple organ failure. Respiratory manifestations are common and range from cough and tachypnea to acute respiratory distress syndrome (ARDS). |
Causative agent |
True |
Cytokine |
Inferred relationship |
Some |
1 |
| Protein kinase C activity assay |
Component |
True |
Cytokine |
Inferred relationship |
Some |
2 |
| Lymphokine assay |
Component |
True |
Cytokine |
Inferred relationship |
Some |
2 |
| Mononuclear cell function assay |
Component |
True |
Cytokine |
Inferred relationship |
Some |
1 |
| Intracellular free calcium assay |
Component |
True |
Cytokine |
Inferred relationship |
Some |
1 |
| Cytokine therapy |
Direct substance |
True |
Cytokine |
Inferred relationship |
Some |
1 |
FHIR