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73187006: Thyroxine (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with molecular messenger mechanism of action (substance)\Hormone\Thyroid hormone\Thyroxine

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Hormone\Thyroid hormone\Thyroxine

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Substance with phenol structure\Iodothyronine\Thyroxine

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Thyroxine	Is a	Thyroid hormone	true	Inferred relationship	Some
Thyroxine	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Thyroid hormone (disposition)	true	Inferred relationship	Some
Thyroxine	Is a	Hormone	false	Inferred relationship	Some
Thyroxine	Is a	Drug allergen	false	Inferred relationship	Some
Thyroxine	Is a	Iodothyronine	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Prealbumin bound thyroxine	Is a	False	Thyroxine	Inferred relationship	Some
Albumin bound thyroxine	Is a	False	Thyroxine	Inferred relationship	Some
Thyroxine binding globulin bound thyroxine	Is a	False	Thyroxine	Inferred relationship	Some
Levothyroxine sodium	Is a	False	Thyroxine	Inferred relationship	Some
Dextrothyroxine (substance)	Is a	False	Thyroxine	Inferred relationship	Some
Free thyroxine	Is a	False	Thyroxine	Inferred relationship	Some
Thyroxine uptake measurement	Has measured component	False	Thyroxine	Inferred relationship	Some
Thyroxine/thyroxine binding globulin measurement (procedure)	Has measured component	False	Thyroxine	Inferred relationship	Some
Thyroxine/triiodothyronine uptake index measurement	Has measured component	False	Thyroxine	Inferred relationship	Some
Thyrotoxicosis on thyroxine therapy	Causative agent	True	Thyroxine	Inferred relationship	Some	1
Accidental thyroxin poisoning	Causative agent	False	Thyroxine	Inferred relationship	Some
forgiftning med thyroxin, uvist med hvilken hensigt	Causative agent	False	Thyroxine	Inferred relationship	Some	1
accidentel forgiftning med levotyroxinnatrium	Causative agent	False	Thyroxine	Inferred relationship	Some
tilsigtet forgiftning med levothyroxinnatrium	Causative agent	False	Thyroxine	Inferred relationship	Some
forgiftning med levothyroxinnatrium, uvist med hvilken hensigt	Causative agent	False	Thyroxine	Inferred relationship	Some
Thyroxine adverse reaction	Causative agent	True	Thyroxine	Inferred relationship	Some	1
Total thyroxine measurement	Has measured component	False	Thyroxine	Inferred relationship	Some
Thyroxine measurement	Has measured component	False	Thyroxine	Inferred relationship	Some
T4 newborn screen	Has measured component	False	Thyroxine	Inferred relationship	Some
Serum T4 measurement	Has measured component	False	Thyroxine	Inferred relationship	Some
Plasma total T4 measurement	Has measured component	False	Thyroxine	Inferred relationship	Some
Serum total T4 measurement	Has measured component	False	Thyroxine	Inferred relationship	Some
Thyroxine uptake measurement	Component	True	Thyroxine	Inferred relationship	Some	1
Thyroxine/thyroxine binding globulin measurement (procedure)	Component	True	Thyroxine	Inferred relationship	Some	1
Thyroxine/triiodothyronine uptake index measurement	Component	True	Thyroxine	Inferred relationship	Some	1
Accidental thyroxin overdose	Causative agent	True	Thyroxine	Inferred relationship	Some	1
overdosis af thyroxin, uvist med hvilken hensigt	Causative agent	False	Thyroxine	Inferred relationship	Some	1
Total thyroxine measurement	Component	True	Thyroxine	Inferred relationship	Some	1
Thyroxine measurement	Component	True	Thyroxine	Inferred relationship	Some	1
T4 newborn screen	Component	True	Thyroxine	Inferred relationship	Some	1
Serum T4 measurement	Component	False	Thyroxine	Inferred relationship	Some	2
Plasma total T4 measurement	Component	True	Thyroxine	Inferred relationship	Some	1
Serum total T4 measurement	Component	True	Thyroxine	Inferred relationship	Some	1
Thyroxine sodium 25micrograms tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thyroxine	Inferred relationship	Some
Thyroxine sodium 50micrograms tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thyroxine	Inferred relationship	Some
Thyroxine sodium 100micrograms tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thyroxine	Inferred relationship	Some
Thyroxine sodium	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thyroxine	Inferred relationship	Some
Allergy to thyroxine	Causative agent	False	Thyroxine	Inferred relationship	Some
Product containing thyroxine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Thyroxine	Inferred relationship	Some	1
Product containing dextrothyroxine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Thyroxine	Inferred relationship	Some
Accidental thyroxin poisoning	Causative agent	True	Thyroxine	Inferred relationship	Some	1
Intentional thyroxin poisoning	Causative agent	True	Thyroxine	Inferred relationship	Some	1
Intentional thyroxin overdose	Causative agent	True	Thyroxine	Inferred relationship	Some	1
Allergy to thyroxine	Causative agent	True	Thyroxine	Inferred relationship	Some	1
Levothyroxine (substance)	Is a	False	Thyroxine	Inferred relationship	Some
Dextrothyroxine sodium	Is a	False	Thyroxine	Inferred relationship	Some
Thyroxine only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Thyroxine	Inferred relationship	Some	1
Equilibrium dialysis radioimmunoassay method for free thyroxine measurement	Component	False	Thyroxine	Inferred relationship	Some	3
T4 free measurement	Component	True	Thyroxine	Inferred relationship	Some	2
Serum free T4 measurement	Component	False	Thyroxine	Inferred relationship	Some	3
Plasma free T4 measurement	Component	False	Thyroxine	Inferred relationship	Some	3
Thyroxine binding globulin bound thyroxine	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Thyroxine	Inferred relationship	Some
Prealbumin bound thyroxine	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Thyroxine	Inferred relationship	Some
Albumin bound thyroxine	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Thyroxine	Inferred relationship	Some
Equilibrium dialysis radioimmunoassay method for free thyroxine measurement	Component	True	Thyroxine	Inferred relationship	Some	2
Serum free T4 measurement	Component	True	Thyroxine	Inferred relationship	Some	2
Plasma free T4 measurement	Component	True	Thyroxine	Inferred relationship	Some	2
Serum T4 measurement	Component	True	Thyroxine	Inferred relationship	Some	1

Reference Sets

Description inactivation indicator reference set

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Id	Description	Lang	Type	Status	Case?	Module
121547019	Thyroxine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
813547018	Thyroxine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3722037011	3,5,3'5' tetraiodothyronine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3723128017	T4 - thyroxine	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
2728651000005112	Thyroxin	da	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Danish module (core metadata concept)