721306009: Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)

SNOMED CT Concept\Clinical finding (finding)\...

\Mass of body structure\Mass of lymphoreticular structure\Neoplasm of bone marrow (disorder)\Therapy-related myelodysplastic syndrome (disorder)\Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)
\Mass of body structure\Hematologic neoplasm\Neoplasm affecting hematopoietic structure (disorder)\Therapy-related myelodysplastic syndrome (disorder)\Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)

\Disease\Disorder of hematopoietic cell proliferation (disorder)\Myeloproliferative disorder (disorder)\Therapy-related myelodysplastic syndrome (disorder)\Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)
\Disease\Neoplasm and/or hamartoma (disorder)\Neoplastic disease\Neoplasm of hematopoietic cell type (disorder)\Malignant neoplasm of lymphoid, hematopoietic and/or related tissue (disorder)\Therapy-related myelodysplastic syndrome (disorder)\Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)
\Disease\Neoplasm and/or hamartoma (disorder)\Neoplastic disease\Malignant neoplastic disease (disorder)\Malignant neoplasm of lymphoid, hematopoietic and/or related tissue (disorder)\Therapy-related myelodysplastic syndrome (disorder)\Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)
\Disease\Neoplasm and/or hamartoma (disorder)\Neoplastic disease\Hematologic neoplasm\Neoplasm affecting hematopoietic structure (disorder)\Therapy-related myelodysplastic syndrome (disorder)\Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)
\Disease\Disorder of body system\Disorder of hematopoietic structure (disorder)\Neoplasm affecting hematopoietic structure (disorder)\Therapy-related myelodysplastic syndrome (disorder)\Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)
\Disease\Disorder of body system\Disorder of hematopoietic structure (disorder)\Bone marrow disorder\Myeloproliferative disorder (disorder)\Therapy-related myelodysplastic syndrome (disorder)\Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)
\Disease\Disorder of body system\Disorder of hematopoietic structure (disorder)\Bone marrow disorder\Neoplasm of bone marrow (disorder)\Therapy-related myelodysplastic syndrome (disorder)\Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)
\Disease\Disorder of body system\Hematologic neoplasm\Neoplasm affecting hematopoietic structure (disorder)\Therapy-related myelodysplastic syndrome (disorder)\Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Mar 2023. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3324921010 Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3324922015 Therapy related acute myeloid leukemia and myelodysplastic syndrome en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3324923013 Therapy related acute myeloid leukaemia and myelodysplastic syndrome en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)	Is a	Acute myeloid leukemia, disease	false	Inferred relationship	Some
Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)	Associated morphology	behandlings-relateret akut myeloid leukæmi og myelodysplastisk syndrom	false	Inferred relationship	Some	1
Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)	Finding site	Bone marrow structure (body structure)	true	Inferred relationship	Some	1
Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)	Is a	Therapy-related myelodysplastic syndrome (disorder)	true	Inferred relationship	Some
Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)	Associated morphology	Myeloid neoplasm post cytotoxic therapy (morphologic abnormality)	true	Inferred relationship	Some	1

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Therapy related acute myeloid leukaemia due to and following administration of antineoplastic agent	Is a	False	Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)	Inferred relationship	Some
A subgroup of therapy-related myeloid neoplasms (t-MN), associated with treatment of an unrelated neoplastic disease with radiation. The neoplastic cells typically harbor unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. Patients frequently present with multilineage dysplasia and cytopenias 5-10 years after exposure.	Is a	False	Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)	Inferred relationship	Some
A subgroup of therapy-related myeloid neoplasms (t-MN), associated with a treatment of an unrelated neoplastic or autoimmune disease with cytotoxic agents, like cyclophosphamid, platins, melphalan and others. The neoplastic cells typically harbour unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. It usually presents with multilineage dysplasia and cytopenias 5-10 years after exposure, with symptoms related to the degree of bone marrow failure and the corresponding cytopenia (fatigue, bleeding and bruising, recurrent infections, bone pain).	Is a	False	Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)	Inferred relationship	Some
A subgroup of therapy-related myeloid neoplasms (t-MN), associated with treatment of an unrelated neoplastic disease with cytotoxic agents, like etoposide, doxorubicin, daunorubicin and others. The neoplastic cells often show rearrangements involving the mixed lineage leukaemia gene at 11q23. This subgroup of t-MN is typically associated with overt leukaemia, without preceding myelodysplastic syndrome, developing 2-3 years after exposure, presenting with non-specific symptoms related to ineffective haematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement.	Is a	False	Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)	Inferred relationship	Some

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3324921010	Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3324922015	Therapy related acute myeloid leukemia and myelodysplastic syndrome	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3324923013	Therapy related acute myeloid leukaemia and myelodysplastic syndrome	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core