4830009: Hyperpigmentation (morphologic abnormality)

SNOMED CT Concept\Body structure\Body structure, altered from its original anatomical structure (morphologic abnormality)\Morphologically abnormal structure\...

\Lesion (morphologic abnormality)\Pigment alteration\Pigment deposition\Hyperpigmentation

\Deposition\Pigment deposition\Hyperpigmentation

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

9053010 Hyperpigmentation en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

785853016 Hyperpigmentation (morphologic abnormality) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

2609801000005115 Hyperpigmentering da Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Danish module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Hyperpigmentation	Is a	Pigment deposition	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Villonodulær synovit uden specificeret lokalisation	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	2
Villonodulær synovit, med anden specificeret lokalisation	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	2
Villonodulær synovit i andet tarsalled	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Villonodulær synovit, ikke nærmere specificeret	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	2
Hyperpigmentation of skin	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Parasitic melanoderma	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Post-inflammatory hyperpigmentation	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Senile melanoderma (disorder)	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Chloasma traumaticum	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Chloasma caloricum (disorder)	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Zosteriform reticulate hyperpigmentation	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Chloasma toxicum	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Chloasma bronzinum	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Cantu's syndrome	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
black heel	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	2
Addison melanoderma	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Chloasma cachecticorum	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Melasma gravidarum (disorder)	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Drug-induced melasma	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Arsenic-induced skin pigmentation (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Symptomgivende chloasma	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Melanoderma	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Chloasma NOS	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Reticulate acropigmentation of Kitamura	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Penile hypermelanosis	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Idiopathic chloasma	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Melanoderma cachecticorum	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Symmetrical dyschromatosis of extremities	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Chloasma hepaticum	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Hyperchromic lesions of pinta	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Traumatic hemorrhage into heel that persists as black dots.	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Periorbital hypermelanosis	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Vulvovaginal hypermelanosis	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Hypermelanosis of the eyelids due to hyperthyroidism (disorder)	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	3
Chloasma	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
kongenit hyperpigmentering	Is a	False	Hyperpigmentation	Inferred relationship	Some
Melanosis	Is a	True	Hyperpigmentation	Inferred relationship	Some
Achromic AND hyperchromic skin lesions of pinta	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	4
Lichen planus (LP) pigmentosus is a rare variant of cutaneous lichen planus characterized by the presence of hyperpigmented lichenoid lesions in sun-exposed or flexural areas of the body.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	3
X-linked reticulate pigmentary disorder is an extremely rare skin disease described in only four families to date and characterized in males by diffuse reticulate brown hyperpigmented skin lesions developing in early childhood and a variety of systemic manifestations (recurrent pneumonia, corneal opacification, gastrointestinal inflammation, urethral stricture, failure to thrive, hypohidrosis, digital clubbing, and unruly hair and flared eyebrows), while in females, there is only cutaneous involvement with the development in early childhood of localized brown hyperpigmented skin lesions following the lines of Blaschko. This disease was first considered as a cutaneous amyloidosis, but amyloid deposits are an inconstant feature.	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	2
Terminal osseous dysplasia-pigmentary defects syndrome is characterized by malformation of the hands and feet, pigmentary skin lesions on the face and scalp and digital fibromatosis.	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	4
øget melaninpigmentering	Is a	False	Hyperpigmentation	Inferred relationship	Some
Circumscribed hypermelanosis (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Dermatopathia pigmentosa reticularis	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
X-linked reticulate pigmentary disorder is an extremely rare skin disease described in only four families to date and characterized in males by diffuse reticulate brown hyperpigmented skin lesions developing in early childhood and a variety of systemic manifestations (recurrent pneumonia, corneal opacification, gastrointestinal inflammation, urethral stricture, failure to thrive, hypohidrosis, digital clubbing, and unruly hair and flared eyebrows), while in females, there is only cutaneous involvement with the development in early childhood of localized brown hyperpigmented skin lesions following the lines of Blaschko. This disease was first considered as a cutaneous amyloidosis, but amyloid deposits are an inconstant feature.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
A rare genetic adrenal disorder with characteristics of congenital bronzed hyperpigmentation, cutis laxa of the hands and feet, body disproportion (comprising large hands, feet, nose and ears), hirsutism and severe intellectual disability. Patients additionally present hyperadrenocorticism, cushingoid features, premature adrenarche and diabetes mellitus, as well as skeletal deformities (not present at birth and which progress with age). There have been no further descriptions in the literature since 1981.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
A rare genetic malformation syndrome with characteristics of microcephaly, borderline intellectual disability, hyperpigmentation of the skin, short stature, and ventricular extrasystoles. Cardiac syncope may also be associated. There have been no further descriptions in the literature since 1975.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Carney complex-trismus-pseudocamptodactyly syndrome is a rare genetic heart-hand syndrome characterized by typical manifestations of the Carney complex (spotty pigmentation of the skin, familial cardiac and cutaneous myxomas and endocrinopathy) associated with trismus and distal arthrogryposis (presenting as involuntary contraction of distal and proximal interphalangeal joints of hands evident only on dorsiflexion of wrist and similar lower-limb contractures producing foot deformities).	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	3
Terminal osseous dysplasia-pigmentary defects syndrome is characterized by malformation of the hands and feet, pigmentary skin lesions on the face and scalp and digital fibromatosis.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
A rare endocrine disease characterized by lentigines with a specific peri-orifical distribution, blue nevus, myxomas, various endocrine tumors including primary pigmented nodular adrenocortical disease (PPNAD), acromegaly, thyroid tumors, and a wide range of other tumors.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Inherited cutaneous hyperpigmentation	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
A rare genetic neurological disease characterized by silvery hair, profound dysfunction of central nervous system, abnormal melanocytes and melanosomes and abnormal inclusion bodies in fibroblast and other cells.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Dyschromatosis universalis	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Naegeli-Franceschetti-Jadassohn syndrome	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
A rare genetic congenital limb malformation syndrome with characteristics of short stature, sparse scalp hair, hypoplastic, proximally placed thumbs and skin hyperpigmentation with areas of 'raindrop' depigmentation. Presence of a single, upper central incisor has also been reported. There have been no further descriptions in the literature since 1988.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
A rare syndromic hyperpigmentation of the skin with characteristics of multiple lentigines and cafe-au-lait spots associated with hiatal hernia and peptic ulcer, hypertelorism and myopia. There have been no further descriptions in the literature since 1982.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Pigmented hairy epidermal nevus of left lower limb (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of right lower limb (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of right upper limb	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of left upper limb (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of trunk	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Dermopathy due to type 2 diabetes mellitus (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Pretibial pigmental patches due to diabetes mellitus (disorder)	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	2
Diabetic dermopathy	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Diabetic thick skin syndrome	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Rubeosis faciei due to diabetes mellitus (disorder)	Associated morphology	False	Hyperpigmentation	Inferred relationship	Some	1
Syndrome with characteristics of the association of osteopathia striata (longitudinal striations through most of the long bones) with a macular hyperpigmented dermopathy and a white forelock. It has been observed in a woman and her two daughters, whereas her son is unaffected. X-linked or autosomal dominant inheritance is proposed.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Dermopathy due to type 1 diabetes mellitus (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pretibial pigmental patches due to diabetes mellitus (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Acquired acanthosis nigricans	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Acanthosis nigricans due to type 2 diabetes mellitus	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Hyperpigmentation of eyelid	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Progressive cribriform and zosteriform hyperpigmentation (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Palmoplantar hyperkeratosis-hyperpigmentation syndrome of Cantu (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	3
Legius syndrome	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
A rare multiple congenital anomalies/dysmorphic syndrome with intellectual disability characterized by infantile onset of global developmental delay, severe intellectual disability, growth deficiency, microcephaly, strabismus, blue-gray sclerae, and extensive Mongolian spots. Some patients also present with epilepsy. Brain imaging may demonstrate variable abnormalities including cerebral atrophy, thin corpus callosum, ventriculomegaly, or arachnoid cysts.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
A rare genetic disease characterized by the presence of multiple café-au-lait macules and elevated rates of sister chromatid exchange demonstrated on cytogenetic testing. Pre- and postnatal growth deficiency with short stature, microcephaly, mild developmental delay, cardiomyopathy, and symptomatic gastro-esophageal reflux have also been described, while malar rash is typically absent.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Neurofibromatosis type 6 (NF6), also referred as café-au-lait spots syndrome, is a cutaneous disorder characterized by the presence of several café-au-lait (CAL) macules without any other manifestations of neurofibromatosis or any other systemic disorder.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Skin graft hyperpigmentation (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	3
Laser-induced hyperpigmentation (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Hyperpigmentation of right eyelid and periocular area (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Hyperpigmentation of right lower eyelid and periocular area (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Hyperpigmentation of left eyelid and periocular area (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Hyperpigmentation of left lower eyelid and periocular area (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
A disorder defined as retinal pigment disturbances including hypopigmentation and hyperpigmentation in colour fundus photographs that typically corresponded to hyperfluorescence and hypofluorescence in fluorescein angiogram images within or overlapping areas previously occupied by CNV (choroidal neovascularisation).	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of left lower eyelid (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal naevus of right lower eyelid	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of neck (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of face	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of scalp (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of lower eyelid (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of left upper eyelid	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of right upper eyelid (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of upper eyelid	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
A combination of congenital hyperpigmented and hypopigmented skin lesions coexisting in the same individual.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
Linear atrophoderma of Moulin (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
A rare mosaic form of Legius syndrome with findings typical of Legius syndrome, namely multiple cafe-au-lait macules (CALMs) with or without axillary or inguinal freckling. Mosaic form is caused by postzygotic pathogenic variants in SPRED1 gene. In mosaic Legius syndrome the allelic/tissue distribution of the pathogenic SPRED1-variant clearly suggests mosaicism and/or the distribution of CALMs is segmental. The phenotype can be milder than in Legius syndrome.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	1
A rare, syndromic, benign, epidermal nevus syndrome characterized by the association of a Becker nevus (i.e. circumscribed, unilateral, irregularly shaped, hyperpigmented macules, with or without hypertrichosis and/or acneiform lesions, occurring predominantly on the anterior upper trunk or scapular region) with ipsilateral breast hypoplasia or other, typically hypoplastic, skeletal, cutaneous, and/or muscular defects. These include pectoralis major hypoplasia, supernumerary nipples, vertebral defects, scoliosis, limb asymmetry, odontomaxillary hypoplasia and lipoatrophy.	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of left ear (disorder)	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of bilateral ears	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	2
Pigmented hairy epidermal nevus of bilateral ears	Associated morphology	True	Hyperpigmentation	Inferred relationship	Some	3

Start Previous Page 3 of 4 End

Reference Sets

GB English

US English

Back to Start

Id	Description	Lang	Type	Status	Case?	Module
9053010	Hyperpigmentation	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
785853016	Hyperpigmentation (morphologic abnormality)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2609801000005115	Hyperpigmentering	da	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Danish module (core metadata concept)