410922003: Product containing precisely bisoprolol 2.5 milligram and hydrochlorothiazide 6.25 milligram/1 each conventional release oral tablet (clinical drug)

Status: retired, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2021. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3677105015 Bisoprolol 2.5 mg and hydrochlorothiazide 6.25 mg oral tablet en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3677106019 Product containing precisely bisoprolol 2.5 milligram and hydrochlorothiazide 6.25 milligram/1 each conventional release oral tablet (clinical drug) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

4725511000005110 bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet da Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Danish module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Is a	Bisoprolol fumarate + hydrochlorothiazide	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	Hydrochlorothiazide (substance)	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	Bisoprolol fumarate (substance)	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Has manufactured dose form	A solid single-dose preparation obtained by compressing uniform volumes of particulate solids or by extrusion or moulding. Tablets may be single layer tablets resulting from a single compression of particles and or multilayer tablets consisting of concentric or parallel layers obtained by successive compressions of particles of different composition.	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Is a	Product containing bisoprolol and hydrochlorothiazide (medicinal product)	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	Bisoprolol (substance)	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Has manufactured dose form	Oral tablet	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Is a	Product manufactured as oral dose form (product)	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Is a	Bisoprolol-containing product in oral dose form	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Is a	Hydrochlorothiazide-containing product in oral dose form	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	Hydrochlorothiazide (substance)	false	Inferred relationship	Some	1
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	Hydrochlorothiazide (substance)	false	Inferred relationship	Some	1
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Has presentation strength numerator value	6.25	false	Inferred relationship	Some	1
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	This attribute specifies the numerator unit for the presentation strength of a product.	mg	false	Inferred relationship	Some	1
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Has presentation strength denominator value	en	false	Inferred relationship	Some	1
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	This attribute specifies the denominator unit for the presentation strength of a product.	Tablet (unit of presentation)	false	Inferred relationship	Some	1
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	Bisoprolol (substance)	false	Inferred relationship	Some	2
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	Bisoprolol (substance)	false	Inferred relationship	Some	2
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Has presentation strength numerator value	2.5	false	Inferred relationship	Some	2
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	This attribute specifies the numerator unit for the presentation strength of a product.	mg	false	Inferred relationship	Some	2
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Has presentation strength denominator value	en	false	Inferred relationship	Some	2
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	This attribute specifies the denominator unit for the presentation strength of a product.	Tablet (unit of presentation)	false	Inferred relationship	Some	2
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	Bisoprolol (substance)	false	Inferred relationship	Some	1
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Has presentation strength numerator value	2.5	false	Inferred relationship	Some	1
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	Hydrochlorothiazide (substance)	false	Inferred relationship	Some	2
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Has presentation strength numerator value	6.25	false	Inferred relationship	Some	2
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Has unit of presentation	Tablet (unit of presentation)	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Is a	Product containing bisoprolol and hydrochlorothiazide in oral dose form (medicinal product form)	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	Hydrochlorothiazide (substance)	false	Inferred relationship	Some	2
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	Bisoprolol (substance)	false	Inferred relationship	Some	1
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Count of base of active ingredient	to	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Is a	Bisoprolol and hydrochlorothiazide only product in oral dose form	false	Inferred relationship	Some
bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	Plays role	Diuretic therapeutic role	false	Inferred relationship	Some

Inbound Relationships

Type

Active

Source

Characteristic

Refinability

Group

Reference Sets

Concept inactivation indicator reference set

REPLACED BY association reference set (foundation metadata concept)

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Id	Description	Lang	Type	Status	Case?	Module
3677105015	Bisoprolol 2.5 mg and hydrochlorothiazide 6.25 mg oral tablet	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3677106019	Product containing precisely bisoprolol 2.5 milligram and hydrochlorothiazide 6.25 milligram/1 each conventional release oral tablet (clinical drug)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4725511000005110	bisoprololfumarat 2,5 mg + hydrochlorthiazid 6,25 mg tablet	da	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Danish module (core metadata concept)