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397343002: Therapy-related acute myeloid leukemia and myelodysplastic syndrome, alkylating agent-related type (morphologic abnormality)


    Status: retired, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Mar 2023. Module: SNOMED CT core

    Descriptions:

    Id Description Lang Type Status Case? Module
    1765261016 Therapy-related acute myeloid leukemia and myelodysplastic syndrome, alkylating agent-related type (morphologic abnormality) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core
    1773086019 Therapy-related acute myeloid leukaemia and myelodysplastic syndrome, alkylating agent-related type en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
    1774372017 Therapy-related acute myeloid leukemia and myelodysplastic syndrome, alkylating agent-related type en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
    1785803015 Therapy-related AML and myelodysplastic syndrome, alkylating agent-related type en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core
    3487211000005116 behandlingsrelateret akut myeloid leukæmi og myeloblastært syndrom af alkylerende middel-relateret type da Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Danish module (core metadata concept)


    0 descendants.

    Expanded Value Set


    Outbound Relationships Type Target Active Characteristic Refinability Group Values
    behandlingsrelateret akut myeloid leukæmi og myeloblastært syndrom af alkylerende middel-relateret type Is a behandlings-relateret akut myeloid leukæmi og myelodysplastisk syndrom false Inferred relationship Some

    Inbound Relationships Type Active Source Characteristic Refinability Group
    A subgroup of therapy-related myeloid neoplasms (t-MN), associated with a treatment of an unrelated neoplastic or autoimmune disease with cytotoxic agents, like cyclophosphamid, platins, melphalan and others. The neoplastic cells typically harbour unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. It usually presents with multilineage dysplasia and cytopenias 5-10 years after exposure, with symptoms related to the degree of bone marrow failure and the corresponding cytopenia (fatigue, bleeding and bruising, recurrent infections, bone pain). Associated morphology False behandlingsrelateret akut myeloid leukæmi og myeloblastært syndrom af alkylerende middel-relateret type Inferred relationship Some 1

    Reference Sets

    Concept inactivation indicator reference set

    REPLACED BY association reference set (foundation metadata concept)

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