396065004: Folinic acid (substance)

SNOMED CT Concept\Substance\...

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Vitamin\Water-soluble vitamin\Vitamin B and/or vitamin B derivative (substance)\Folinic acid (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Pteridine\Pterins\Folinic acid (substance)

\Biological substance (substance)\Nutrients\Vitamin\Water-soluble vitamin\Vitamin B and/or vitamin B derivative (substance)\Folinic acid (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Folinic acid (substance)	Is a	Vitamin	false	Inferred relationship	Some
Folinic acid (substance)	Is a	Vitamin B and/or vitamin B derivative (substance)	true	Inferred relationship	Some
Folinic acid (substance)	Is a	Pterins	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing folinic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
Folinic acid adverse reaction (disorder)	Causative agent	True	Folinic acid (substance)	Inferred relationship	Some	1
Allergy to folinic acid	Causative agent	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 10 mg/ml injektionsvæske, opløsning, ampul a 5 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 10 mg/ml injektionsvæske, opløsning, hætteglas a 10 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 10 mg/ml injektionsvæske, opløsning, ampul a 2,5 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 10 mg/ml injektionsvæske, opløsning, hætteglas a 17,5 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 10 mg/ml injektionsvæske, opløsning, hætteglas a 35 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 7,5 mg/ml injektionsvæske, opløsning, ampul a 2 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 10 mg/ml injektionsvæske, opløsning, hætteglas a 30 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
Folinic acid 15 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 3 mg/ml injektionsvæske, opløsning, ampul a 1 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 15 mg pulver til injektionsvæske, opløsning, hætteglas	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 30 mg pulver til injektionsvæske, opløsning, hætteglas	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 3 mg/ml injektionsvæske, opløsning, ampul a 10 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
Folinic acid 15mg injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
Product containing precisely calcium folinate 15 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 50 mg/ml injektionsvæske, opløsning, hætteglas a 2 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
Folinic acid 50mg/mL injection solution 8mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
Folinic acid 50mg/mL injection solution 18mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
Levofolinic acid (substance)	Is a	False	Folinic acid (substance)	Inferred relationship	Some
Folinic acid preparation	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
calciumfolinatpræparat	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
leucovorincalcium 350 mg pulver til injektionsvæske	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
leucovorincalcium 200 mg pulver til injektionsvæske	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
leucovorincalcium 50 mg pulver til injektionsvæske	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
leucovorincalcium 100 mg pulver til injektionsvæske	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
leucovorincalcium 500 mg pulver til injektionsvæske	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
levofolinsyre 50 mg/5 ml injektionsvæske	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
Folinic acid 15mg injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
Product containing precisely calcium folinate 5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 100 mg/2 ml injektionsvæske	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 400 mg/8 ml injektionsvæske	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
folinsyre 900 mg/18 ml injektionsvæske	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some
Product containing folinic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Folinic acid (substance)	Inferred relationship	Some	1
Allergy to folinic acid	Causative agent	True	Folinic acid (substance)	Inferred relationship	Some	1
Folinic acid 15 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Folinic acid (substance)	Inferred relationship	Some	1
Folinic acid 15 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Folinic acid (substance)	Inferred relationship	Some	1
Folinic acid 15 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Folinic acid (substance)	Inferred relationship	Some	1
Folinic acid-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Folinic acid (substance)	Inferred relationship	Some	1
Sodium folinate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Folinic acid (substance)	Inferred relationship	Some
Product containing only folinic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Folinic acid (substance)	Inferred relationship	Some	1
Folinic acid only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Folinic acid (substance)	Inferred relationship	Some	1
Calcium folinate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Folinic acid (substance)	Inferred relationship	Some
Product containing only folinic acid in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Folinic acid (substance)	Inferred relationship	Some	1
FOLFIRI antineoplastic chemotherapy regimen	Direct substance	True	Folinic acid (substance)	Inferred relationship	Some	3
FOLFIRINOX antineoplastic chemotherapy regimen	Direct substance	True	Folinic acid (substance)	Inferred relationship	Some	4
Folinic acid-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Folinic acid (substance)	Inferred relationship	Some	1
Product containing precisely folinic acid (as calcium folinate) 10 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Folinic acid (substance)	Inferred relationship	Some	1
Product containing precisely folinic acid (as calcium folinate) 7.5 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Folinic acid (substance)	Inferred relationship	Some	1
Product containing precisely folinic acid (as calcium folinate) 15 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Folinic acid (substance)	Inferred relationship	Some	1
Product containing precisely folinic acid (as calcium folinate) 3 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Folinic acid (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1470005014	Folinic acid (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1489690014	Folinic acid	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3768234016	Leucovorin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3265051000005118	folinsyre	da	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Danish module (core metadata concept)
4851741000005119	folininsyre	da	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Danish module (core metadata concept)