387094004: Proguanil (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Antiprotozoal\Substance with antimalarial mechanism of action (substance)\Biguanide antimalarial agent\Proguanil

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Anti-infective agent (substance)\Antiprotozoal\Substance with antimalarial mechanism of action (substance)\Biguanide antimalarial agent\Proguanil

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Biguanide (substance)\Biguanide antimalarial agent\Proguanil

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Proguanil	Is a	Substance with antimalarial mechanism of action (substance)	false	Inferred relationship	Some
Proguanil	Is a	Biguanide antimalarial agent	true	Inferred relationship	Some
Proguanil	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Antimalarial (disposition)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing proguanil (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Proguanil	Inferred relationship	Some	1
Accidental proguanil poisoning	Causative agent	False	Proguanil	Inferred relationship	Some
Intentional proguanil poisoning	Causative agent	False	Proguanil	Inferred relationship	Some
forgiftning med proguanil, uvist med hvilken hensigt	Causative agent	False	Proguanil	Inferred relationship	Some	1
Proguanil adverse reaction	Causative agent	True	Proguanil	Inferred relationship	Some	1
Allergy to proguanil (finding)	Causative agent	False	Proguanil	Inferred relationship	Some
Proguanil overdose	Causative agent	True	Proguanil	Inferred relationship	Some	1
Accidental proguanil overdose	Causative agent	True	Proguanil	Inferred relationship	Some	1
Intentional proguanil overdose	Causative agent	True	Proguanil	Inferred relationship	Some	1
overdosis af proguanil, uvist med hvilken hensigt	Causative agent	False	Proguanil	Inferred relationship	Some	1
Proguanil hydrochloride (substance)	Is a	False	Proguanil	Inferred relationship	Some
Poisoning by proguanil	Causative agent	True	Proguanil	Inferred relationship	Some	1
Accidental proguanil poisoning	Causative agent	True	Proguanil	Inferred relationship	Some	1
Intentional proguanil poisoning	Causative agent	True	Proguanil	Inferred relationship	Some	1
Proguanil hydrochloride 100 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Proguanil	Inferred relationship	Some
Atovaquone+proguanil hydrochloride	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Proguanil	Inferred relationship	Some
atovaquon 250 mg + proguanilhydrochlorid 100 mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Proguanil	Inferred relationship	Some
proguanilhydrochlorid + chloroquinphosphat	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Proguanil	Inferred relationship	Some
proguanilhydrochlorid 100 mg tablet og chloroquinphosphat 250 mg tablet, pakke	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Proguanil	Inferred relationship	Some
proguanilhydrochlorid	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Proguanil	Inferred relationship	Some
atovaquon 62,5 mg + proguanilhydrochlorid 25 mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Proguanil	Inferred relationship	Some
Proguanil	Is a	False	Proguanil	Inferred relationship	Some
Proguanil hydrochloride (substance)	Is a	False	Proguanil	Inferred relationship	Some
Product containing atovaquone and proguanil (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Proguanil	Inferred relationship	Some	2
Allergy to proguanil (finding)	Causative agent	True	Proguanil	Inferred relationship	Some	1
Proguanil-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Proguanil	Inferred relationship	Some	1
atovaquon 62,5 mg + proguanilhydrochlorid 25 mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Proguanil	Inferred relationship	Some	1
atovaquon 62,5 mg + proguanilhydrochlorid 25 mg tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Proguanil	Inferred relationship	Some	1
atovaquon 250 mg + proguanilhydrochlorid 100 mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Proguanil	Inferred relationship	Some	1
atovaquon 250 mg + proguanilhydrochlorid 100 mg tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Proguanil	Inferred relationship	Some	1
Proguanil hydrochloride (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Proguanil	Inferred relationship	Some
Atovaquone- and proguanil-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Proguanil	Inferred relationship	Some	2
atovaquon 250 mg + proguanilhydrochlorid 100 mg tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Proguanil	Inferred relationship	Some	1
atovaquon 62,5 mg + proguanilhydrochlorid 25 mg tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Proguanil	Inferred relationship	Some	1
Product containing only atovaquone and proguanil (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Proguanil	Inferred relationship	Some	2
Product containing only proguanil (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Proguanil	Inferred relationship	Some	1
Atovaquone and proguanil only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Proguanil	Inferred relationship	Some	2
Proguanil only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Proguanil	Inferred relationship	Some	1

Reference Sets

GB English

US English

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Id	Description	Lang	Type	Status	Case?	Module
1481207012	Chlorguanide	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1491867017	Chloroguanide	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1491868010	Proguanil	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3482664011	Proguanil (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4497741000005113	Proguanil	da	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Danish module (core metadata concept)