386858008: Tramadol (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Glutamate receptor antagonist\NMDA receptor antagonist\Tramadol (substance)
\Substance categorized by disposition\Receptor agonist\Opioid receptor agonist\Tramadol (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Opioid receptor agonist\Tramadol (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Analgesic (substance)\Tramadol (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Central nervous system agent (substance)\Psychoactive substance (substance)\Central depressant\Tramadol (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Substance with ether structure\Tramadol (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

1461036010 Tramadol (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

1480973013 Tramadol en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

4496801000005115 Tramadol da Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Danish module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tramadol (substance)	Is a	Non-opioid analgesic (substance)	false	Inferred relationship	Some
Tramadol (substance)	Is a	Opioid receptor agonist	true	Inferred relationship	Some
Tramadol (substance)	Is a	NMDA receptor antagonist	true	Inferred relationship	Some
Tramadol (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	N-methyl-D-aspartate receptor antagonist (disposition)	true	Inferred relationship	Some
Tramadol (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Opioid receptor agonist (disposition)	true	Inferred relationship	Some
Tramadol (substance)	Is a	Central depressant	true	Inferred relationship	Some
Tramadol (substance)	Is a	Drug pseudoallergen by function	false	Inferred relationship	Some
Tramadol (substance)	Is a	Analgesic (substance)	true	Inferred relationship	Some
Tramadol (substance)	Is a	ether	false	Inferred relationship	Some
Tramadol (substance)	Is a	Substance with ether structure	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing tramadol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Tramadol measurement	Component	True	Tramadol (substance)	Inferred relationship	Some	1
tramadolhydrochlorid 50 mg/ml injektionsvæske, opløsning, ampul a 2 ml	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
Tramadol hydrochloride 50 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid 100 mg tablet med modificeret udløsning	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid 150 mg tablet med modificeret udløsning	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid 200 mg tablet med modificeret udløsning	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid 50 mg opløselig tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid 50 mg kapsel med modificeret udløsning	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid kapsel med modificeret udløsning a 100 mg	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid 150 mg kapsel med modificeret udløsning	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid 200 mg kapsel med modificeret frigivelse	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
Product containing precisely tramadol hydrochloride 50 milligram/1 sachet effervescent powder for conventional release oral solution (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
Product containing precisely tramadol hydrochloride 100 milligram/1 sachet effervescent powder for conventional release oral solution (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid 75 mg tablet med modificeret udløsning	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid 300 mg tablet med modificeret udløsning	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
tramadolhydrochlorid 400 mg tablet med modificeret udløsning	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
Tramadol hydrochloride 50 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
Acetaminophen + tramadol hydrochloride	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
Product containing precisely tramadol hydrochloride 50 milligram/1 each conventional release orodispersible tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
Tramadol hydrochloride	Is a	False	Tramadol (substance)	Inferred relationship	Some
Product containing paracetamol and tramadol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
Measurement of tramadol in urine specimen	Component	False	Tramadol (substance)	Inferred relationship	Some	2
Allergy to tramadol	Causative agent	False	Tramadol (substance)	Inferred relationship	Some
Allergy to tramadol	Causative agent	False	Tramadol (substance)	Inferred relationship	Some	2
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Tramadol (substance)	Inferred relationship	Some	2
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some	1
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tramadol (substance)	Inferred relationship	Some	1
Tramadol hydrochloride	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Tramadol (substance)	Inferred relationship	Some
Tramadol hydrochloride 300mg prolonged-release oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tramadol (substance)	Inferred relationship	Some
Tramadol-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Tramadol (substance)	Inferred relationship	Some	2
Product containing paracetamol and tramadol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Product containing tramadol in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Product containing only tramadol (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Paracetamol and tramadol only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Paracetamol and tramadol only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Allergy to tramadol	Causative agent	True	Tramadol (substance)	Inferred relationship	Some	1
Product containing only tramadol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Product containing only tramadol in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Tramadol-containing product in oromucosal dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Product containing only tramadol in oromucosal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Product containing precisely paracetamol 325 milligram and tramadol 37.5 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tramadol (substance)	Inferred relationship	Some	1
Adverse reaction caused by tramadol	Causative agent	True	Tramadol (substance)	Inferred relationship	Some	1
Dexketoprofen and tramadol only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Product containing dexketoprofen and tramadol in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Dexketoprofen and tramadol only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Dexketoprofen- and tramadol-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tramadol (substance)	Inferred relationship	Some	1
Measurement of tramadol in urine specimen	Component	True	Tramadol (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461036010	Tramadol (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480973013	Tramadol	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4496801000005115	Tramadol	da	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Danish module (core metadata concept)