385996000: Nitisinone (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Oxidoreductase inhibitor\Substance with 4-hydroxyphenylpyruvate dioxygenase inhibitor mechanism of action (substance)\Nitisinone (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Oxidoreductase inhibitor\Substance with 4-hydroxyphenylpyruvate dioxygenase inhibitor mechanism of action (substance)\Nitisinone (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\...

\Hydrocarbon\Aromatic hydrocarbon (substance)\Substance with benzene structure\Nitisinone (substance)

\Ketone (substance)\Cyclic ketone\Cyclohexanone\Nitisinone (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

1460175014 Nitisinone (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

1480183011 Nitisinone en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3184091000005111 nitisinon da Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Danish module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Nitisinone (substance)	Is a	Diverse midler	false	Inferred relationship	Some
Nitisinone (substance)	Is a	Allergen class	false	Inferred relationship	Some
Nitisinone (substance)	Is a	Drug allergen	false	Inferred relationship	Some
Nitisinone (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Nitisinone (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Compound or agent that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction US Library of Medicine MESH Descriptor data Accessed 20/01/2017	false	Inferred relationship	Some
Nitisinone (substance)	Is a	kemisk stof specificeret iht. funktion	false	Inferred relationship	Some
Nitisinone (substance)	Is a	Substance with 4-hydroxyphenylpyruvate dioxygenase inhibitor mechanism of action (substance)	true	Inferred relationship	Some
Nitisinone (substance)	Is a	Benzene	false	Inferred relationship	Some
Nitisinone (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	4-hydroxyphenylpyruvate dioxygenase inhibitor	true	Inferred relationship	Some
Nitisinone (substance)	Is a	Cyclohexanone	true	Inferred relationship	Some
Nitisinone (substance)	Is a	Substance with benzene structure	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing nitisinone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nitisinone (substance)	Inferred relationship	Some	1
Nitisinone 2 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Nitisinone (substance)	Inferred relationship	Some
Product containing precisely nitisinone 5 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Nitisinone (substance)	Inferred relationship	Some
Nitisinone 10 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Nitisinone (substance)	Inferred relationship	Some
Orfadin 2mg capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Nitisinone (substance)	Inferred relationship	Some
Nitisinone 2 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Nitisinone (substance)	Inferred relationship	Some	1
Nitisinone 2 mg oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nitisinone (substance)	Inferred relationship	Some	1
Product containing precisely nitisinone 5 milligram/1 each conventional release oral capsule (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Nitisinone (substance)	Inferred relationship	Some	1
Product containing precisely nitisinone 5 milligram/1 each conventional release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nitisinone (substance)	Inferred relationship	Some	1
Nitisinone 10 mg oral capsule	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Nitisinone (substance)	Inferred relationship	Some	1
Nitisinone 10 mg oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nitisinone (substance)	Inferred relationship	Some	1
Nitisinone 2 mg oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nitisinone (substance)	Inferred relationship	Some	1
Product containing precisely nitisinone 5 milligram/1 each conventional release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nitisinone (substance)	Inferred relationship	Some	1
Nitisinone 10 mg oral capsule	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nitisinone (substance)	Inferred relationship	Some	1
Product containing nitisinone in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nitisinone (substance)	Inferred relationship	Some	1
Product containing only nitisinone (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nitisinone (substance)	Inferred relationship	Some	1
Nitisinone only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nitisinone (substance)	Inferred relationship	Some	1
Product containing precisely nitisinone 20 milligram/1 each conventional release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nitisinone (substance)	Inferred relationship	Some	1
Product containing precisely nitisinone 20 milligram/1 each conventional release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nitisinone (substance)	Inferred relationship	Some	1
Product containing precisely nitisinone 4 milligram/1 milliliter conventional release oral suspension (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nitisinone (substance)	Inferred relationship	Some	1
Product containing precisely nitisinone 4 milligram/1 milliliter conventional release oral suspension (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nitisinone (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1460175014	Nitisinone (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1480183011	Nitisinone	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3184091000005111	nitisinon	da	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Danish module (core metadata concept)