28726007: Corneal structure (body structure)

SNOMED CT Concept\Body structure\Anatomical or acquired body structure (body structure)\Anatomical structure\...

\An anatomical structure that consists of the maximal set of organ parts so connected to one another that together they constitute a self-contained unit of macroscopic anatomy, distinct both morphologically and functionally from other such units. Together with other organs, an organ constitutes an organ system or a body part. An organ is divisible into organ parts but not organs (examples: femur, biceps, liver, heart, aorta, sciatic nerve, ovary).\Structure of sensory organ\Eye structure\Eye proper part (body structure)\...

\Eyeball segment structure (body structure)\Anterior eyeball segment structure (body structure)\Conjunctival and/or corneal structures (body structure)\Corneal structure

\Outer coating of eyeball; has parts cornea and sclera\Corneal structure

\Body system structure\Structure of special senses organ system\The eye, ocular adnexa, afferent visual pathways, efferent visual pathways, and pupil innervation pathways\Eye region structure (body structure)\Eye structure\Eye proper part (body structure)\...

\Eyeball segment structure (body structure)\Anterior eyeball segment structure (body structure)\Conjunctival and/or corneal structures (body structure)\Corneal structure

\Outer coating of eyeball; has parts cornea and sclera\Corneal structure

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Corneal structure	Is a	Conjunctival and/or corneal structures (body structure)	true	Inferred relationship	Some
Corneal structure	Is a	Outer coating of eyeball; has parts cornea and sclera	true	Inferred relationship	Some
Corneal structure	del af	Entire anterior segment of eyeball	false	Additional relationship	Some
Corneal structure	del af	Entire tunica fibrosa of eyeball	false	Additional relationship	Some
Corneal structure	Laterality	Side	true	Inferred relationship	Some
Corneal structure	Is a	Anterior eyeball segment structure (body structure)	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Penetrating keratoplasty	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	2
Penetrating keratoplasty with homograft	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	1
Repair of postcataract wound dehiscence with conjunctival flap	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	2
Conjunctival flap, total	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	2
Conjunctival flap, partial	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	2
Recurrent infection of cornea caused by human herpes simplex virus (disorder)	Finding site	True	Corneal structure	Inferred relationship	Some	1
Recurrent inflammation of cornea caused by human herpes simplex virus (disorder)	Finding site	True	Corneal structure	Inferred relationship	Some	1
Congenital corneal leucoma	Finding site	True	Corneal structure	Inferred relationship	Some	1
Neurotrophic keratitis due to diabetes mellitus (disorder)	Finding site	True	Corneal structure	Inferred relationship	Some	2
Corneal deposits due to metabolic disorder	Finding site	True	Corneal structure	Inferred relationship	Some	1
Contact lens-associated corneal infiltrates due to hypoxia	Finding site	True	Corneal structure	Inferred relationship	Some	1
Penetrating keratoplasty with implantation of posterior chamber intraocular lens (procedure)	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	1
Penetrating keratoplasty with implantation of posterior chamber intraocular lens (procedure)	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	3
Penetrating keratoplasty with implantation of posterior chamber intraocular lens (procedure)	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	4
Adjustable refractive surgery (procedure)	Procedure site - Direct (attribute)	False	Corneal structure	Inferred relationship	Some	2
Corneal leukoma (disorder)	Finding site	True	Corneal structure	Inferred relationship	Some	2
Congenital corneal leucoma	Finding site	True	Corneal structure	Inferred relationship	Some	2
Iatrogenic corneal ectasia	Finding site	True	Corneal structure	Inferred relationship	Some	1
Post-surgical neurotrophic keratitis	Finding site	True	Corneal structure	Inferred relationship	Some	2
Neurotrophic keratitis following herpes simplex dendritic keratitis	Finding site	True	Corneal structure	Inferred relationship	Some	2
Corneal ghost vessels	Finding site	True	Corneal structure	Inferred relationship	Some	2
Post-surgical corneal haze	Finding site	True	Corneal structure	Inferred relationship	Some	1
Opacity of cornea due to and following traumatic injury (disorder)	Finding site	True	Corneal structure	Inferred relationship	Some	1
Keratitis caused by parasite (disorder)	Finding site	True	Corneal structure	Inferred relationship	Some	1
Vitreous touch syndrome	Finding site	True	Corneal structure	Inferred relationship	Some	1
Keratocentesis	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	1
A rare lipoprotein metabolism disorder characterised clinically by corneal opacities and sometimes renal failure and haemolytic anaemia, and biochemically by severely reduced HDL cholesterol. Age of onset is variable but most patients are diagnosed during adulthood. Two familial forms of LCAT deficiency have been reported: familial LCAT deficiency characterised by corneal opacities, anaemia and renal insufficiency and Fish-eye disease characterised by corneal opacities and sometimes atherosclerosis. LCAT deficiency is caused by deficient or absent catalytic activity of the LCAT enzyme, which catalyses the formation of cholesterol esters in lipoproteins and is encoded by the LCAT gene (16q22.1). Accumulation of unesterified cholesterol in the body for example in the cornea, erythrocytes and kidneys, is thought to underlie the clinical manifestations.	Finding site	True	Corneal structure	Inferred relationship	Some	1
A form of genetic LCAT (lecithin-cholesterol acyltransferase) deficiency characterised clinically by corneal opacifications, and biochemically by significantly reduced HDL cholesterol and partial LCAT enzyme deficiency. The disease is very rare. Corneal opacities are progressive and are observed from an early age (adolescence or young adulthood) and sometimes result in visual impairment. These lesions are generally more severe than in complete LCAT deficiency and form a mosaic pattern of small dot-like grey-white opacities. Signs of atherosclerosis have only been reported in rare cases although patients have low HDL cholesterol levels. In patients with this disorder, alpha-LCAT activity is abolished, but beta-LCAT activity is preserved. Impaired enzyme function is thought to result in deposition of lipids in the cornea. The disease follows an autosomal recessive pattern of inheritance.	Finding site	True	Corneal structure	Inferred relationship	Some	2
A form of lecithin-cholesterol acyltransferase deficiency (LCAT) characterized clinically by corneal opacities, hemolytic anemia and renal failure and biochemically by severely decreased HDL cholesterol and complete deficiency of the LCAT enzyme. Age of onset and severity of clinical manifestations are variable. Caused by mutations in the LCAT gene (16q22.1) encoding the LCAT enzyme which catalyzes the formation of cholesterol esters in lipoproteins, leading to progressive lipid deposition in body tissues. There is no clear genotype-phenotype correlation since family members with the same mutation have been found to have different clinical and biochemical pictures. Environmental factors or other minor genes may therefore also be involved in the disorder.	Finding site	True	Corneal structure	Inferred relationship	Some	1
A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by developmental delay with intellectual disability, postnatal growth deficiency causing profound limb shortening with proximal and distal segments involvement, narrow chest, abnormalities of the spine, pelvis, and metaphyses, corneal clouding, and patent ductus arteriosus. Dysmorphic facial features include hypertelorism, prominent eyes, depressed nasal bridge, and short upturned nose.	Finding site	True	Corneal structure	Inferred relationship	Some	2
Dehiscence of corneal transplant wound (disorder)	Finding site	True	Corneal structure	Inferred relationship	Some	1
Harvesting of cornea	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	1
A rare genetic eye disease characterized by congenital cataract, microcornea, and corneal opacity, resulting in severe visual impairment or blindness. Depending on the genetic background, other developmental ocular defects may also be present.	Finding site	True	Corneal structure	Inferred relationship	Some	2
A rare genetic eye disease characterized by congenital cataract, microcornea, and corneal opacity, resulting in severe visual impairment or blindness. Depending on the genetic background, other developmental ocular defects may also be present.	Finding site	True	Corneal structure	Inferred relationship	Some	3
Corneal staphyloma	Finding site	True	Corneal structure	Inferred relationship	Some	2
Congenital anterior staphyloma	Finding site	True	Corneal structure	Inferred relationship	Some	4
Keratoglobus (disorder)	Finding site	True	Corneal structure	Inferred relationship	Some	1
Keratoglobus (disorder)	Finding site	False	Corneal structure	Inferred relationship	Some	2
Infiltrate of cornea following laser assisted in situ keratomileusis (disorder)	Finding site	True	Corneal structure	Inferred relationship	Some	1
Xerosis of cornea (finding)	Finding site	True	Corneal structure	Inferred relationship	Some	1
A rare genetic neurometabolic disease with characteristics of prenatal and postnatal growth retardation, hypotonia, failure to thrive, large and late-closing fontanel, development delay, cutis laxa, joint laxity, progeroid appearance and dysmorphic facial features. In addition, corneal opacities, cataracts, myopia, seizures, hyperreflexia and athetoid movements have also been associated.	Finding site	True	Corneal structure	Inferred relationship	Some	1
Pyrroline-5-carboxylate reductase 1 related de Barsy syndrome	Finding site	True	Corneal structure	Inferred relationship	Some	1
Calculation of corneal tissue ablation depth for refractive change (procedure)	Procedure site - Indirect (attribute)	True	Corneal structure	Inferred relationship	Some	1
Excision of pterygium with corneal transplant (procedure)	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	3
Toric photorefractive keratectomy (procedure)	Procedure site - Indirect (attribute)	True	Corneal structure	Inferred relationship	Some	3
Lamellar keratoplasty with autograft	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	1
Repair of filtering bleb by corneal graft	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	2
A rare ophthalmic disorder characterized by periodic inflammatory attacks of the cornea manifesting as unilateral ocular pain, conjunctival hyperemia, photophobia and epiphora lasting for 1 to 3 days, followed by blurred vision for several weeks. Caused by a heterozygous pathogenic variant c.61G>C, p.(Asp21His) in the NLRP3 gene. The pathogenic variant is highly penetrant (95%). The disease is autosomal dominant.	Finding site	True	Corneal structure	Inferred relationship	Some	2
Disorder of cornea following cataract surgery	Finding site	True	Corneal structure	Inferred relationship	Some	2
Ab interno canaloplasty	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	1
Corneal thinning (finding)	Finding site	True	Corneal structure	Inferred relationship	Some	2
Removal of foreign body of cornea by incision	Procedure site - Direct (attribute)	True	Corneal structure	Inferred relationship	Some	2
Corneal disorder caused by monkeypox virus	Finding site	True	Corneal structure	Inferred relationship	Some	1

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Reference Sets

Lateralizable body structure reference set (foundation metadata concept)

Anatomy structure and entire association reference set (foundation metadata concept)

Anatomy structure and part association reference set (foundation metadata concept)

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Id	Description	Lang	Type	Status	Case?	Module
48095018	Cornea	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
483964014	Corneal structure	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
759438018	Corneal structure (body structure)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2617071000005113	cornea	da	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Danish module (core metadata concept)