Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
A rare genetic multisystemic chronic autoimmune disease characterized by the presence of systemic lupus erythematosus symptoms in two or more members of a single family. Patients present a wide spectrum of clinical manifestations, including cutaneous (malar rash, photosensitivity), ocular (keratoconjunctivitis sicca, retinopathy), gastrointestinal (oral ulceration, abdominal pain), cardiac (atherosclerosis, chest pain), pulmonary (serositis, pleurisy), musculoskeletal (arthralgia, myalgia), renal (nephritis, hematuria), obstetrical (increased spontaneous abortions, neonatal lupus), constitutional (fatigue, loss of appetite) and neuropsychiatric (mood and cognitive disorders) involvement, amongst others. |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
2 |
Lupus erythematosus profundus |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Discoid lupus erythematosus of eyelid |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Lupus erythematosus chronicus |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Discoid lupus erythematosus |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Lupus erythematosus migrans |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Lupus erythematosus nodularis |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Lupus erythematosus tumidus |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Lupus erythematosus unguium mutilans |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Lupus erythematosus and erythema multiforme-like syndrome |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Chronic discoid lupus erythematosus |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Chilblain lupus erythematosus |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Subacute cutaneous lupus erythematosus |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Subacute cutaneous lupus erythematosus, annular/polycyclic type (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Subacute cutaneous lupus erythematosus, papulosquamous type (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Lupus erythematosus-multiformt erytem |
Finding site |
False |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Hypertrophic type discoid lupus erythematosus (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Rosaceous type discoid lupus erythematosus (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Discoid lupus erythematosus of mucous membranes (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Discoid lupus erythematosus of oral mucosa (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Discoid lupus erythematosus of genital mucous membranes (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Discoid lupus erythematosus of scalp (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Discoid lupus erythematosus of face (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Discoid lupus erythematosus of lip (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Discoid lupus erythematosus of hands (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Discoid lupus erythematosus of foot (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Disseminated discoid lupus erythematosus (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Lupus erythematosus-associated nail dystrophy (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
5 |
Acute cutaneous lupus erythematosus |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Discoid lupus erythematosus of lower eyelid |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Discoid lupus erythematosus of upper eyelid |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
A rare monogenic form of cutaneous lupus erythematosus characterised by infantile or childhood onset of cold-induced erythematous papules or plaques predominantly on the fingers, toes, nose, cheeks, and ears. Recurrent ulceration of the lesions may lead to necrotic tissue destruction and mutilation. Patients may experience ischaemia of the affected acral regions. Histological findings include cutaneous perivascular inflammatory infiltrates with deposits of immunoglobulins or complement. |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
5 |
Discoid lupus erythematosus of left eyelid |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Discoid lupus erythematosus of skin of right eyelid (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Cutaneous lupus erythematosus |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Discoid lupus erythematosus of right upper eyelid (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Discoid lupus erythematosus of left upper eyelid |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Discoid lupus erythematosus of left lower eyelid (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Discoid lupus erythematosus of right lower eyelid |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
4 |
Rash of systemic lupus erythematosus |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
3 |
Loeys-Dietz syndrome (disorder) |
Finding site |
True |
Connective tissue structure |
Inferred relationship |
Some |
2 |