16110005: Ophthalmoplegia (disorder)

SNOMED CT Concept\Clinical finding (finding)\...

\Finding of movement\Movement disorder\Paralytic syndrome\Ophthalmoplegia
\Finding of movement\Motor dysfunction\Paralysis\Paralytic syndrome\Ophthalmoplegia

\Eye / vision finding\Visual system disorder\Disorder of eye movements\Disorders characterised by eye movement abnormalities that are the result of brain, cranial nerve, or neuromuscular junction dysfunction.\Ophthalmoplegia

\Neurological finding (finding)\Motor nervous system finding\Motor dysfunction\Paralysis\Paralytic syndrome\Ophthalmoplegia

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

27267019 Ophthalmoplegia en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

743069010 Ophthalmoplegia (disorder) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

2027521000005117 Oftalmoplegi da Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Danish module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Ophthalmoplegia	Is a	Disorders characterised by eye movement abnormalities that are the result of brain, cranial nerve, or neuromuscular junction dysfunction.	true	Inferred relationship	Some
Ophthalmoplegia	Finding site	The eye, ocular adnexa, afferent visual pathways, efferent visual pathways, and pupil innervation pathways	false	Inferred relationship	Some
Ophthalmoplegia	Finding site	Structure of nervous system (body structure)	true	Inferred relationship	Some	2
Ophthalmoplegia	Finding site	Eye region structure (body structure)	false	Inferred relationship	Some
Ophthalmoplegia	Finding site	The eye, ocular adnexa, afferent visual pathways, efferent visual pathways, and pupil innervation pathways	true	Inferred relationship	Some	1
Ophthalmoplegia	Interprets	Ocular motility observable	false	Inferred relationship	Some
Ophthalmoplegia	Has interpretation	Abnormal	false	Inferred relationship	Some
Ophthalmoplegia	Is a	Paralytic syndrome	true	Inferred relationship	Some
Ophthalmoplegia	Interprets	Movement	true	Inferred relationship	Some	4
Ophthalmoplegia	Interprets	Movement observable (observable entity)	true	Inferred relationship	Some	3
Ophthalmoplegia	Has interpretation	Absent	true	Inferred relationship	Some	3

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Congenital nuclear ophthalmoplegia	Is a	True	Ophthalmoplegia	Inferred relationship	Some
External ophthalmoplegia	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Progressive supranuclear ophthalmoplegia	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Exophthalmic ophthalmoplegia	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Painful ophthalmoplegia	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Ophthalmoplegia plus syndrome	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Total ophthalmoplegia	Is a	False	Ophthalmoplegia	Inferred relationship	Some
Recurrent painful ophthalmoplegic neuropathy	Is a	False	Ophthalmoplegia	Inferred relationship	Some
Internuclear ophthalmoplegia	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Ophthalmoplegia due to diabetes mellitus (disorder)	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Ophthalmoplegia due to Graves' disease	Is a	True	Ophthalmoplegia	Inferred relationship	Some
A rare late-onset neurodegenerative disease with characteristics of supranuclear gaze palsy, postural instability, progressive rigidity, and mild dementia. Five clinical variants have been described with clinicopathological correlations, with Richardson's syndrome the most common clinical variant. The disease has neuropathological manifestations of neuronal loss, gliosis with astrocytic plaques and accumulation of tau-immunoreactive neurofibrillary tangles in specific brain areas. The differences in the rate and areas of accumulation of phosphorylated tau protein correlate with the five clinical variants. The disease is a 4R tauopathy composed of a preponderance of four-repeat (exon 10 positive) tau isoforms and a characteristic biochemical profile (doublet tau 64 and tau 69). The MAPT H1-clade specific sub-haplotype, H1c, is a risk factor for this disease.	Is a	True	Ophthalmoplegia	Inferred relationship	Some
A rare bulbospinal muscular atrophy characterised by generalised neonatal hypotonia, progressive pontobulbar and spinal palsy, pyramidal signs, and deafness. External ophthalmoplegia and bilateral mydriasis are typical signs. There have been no further descriptions in the literature since 1994.	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Ophthalmoplegia due to abetalipoproteinemia (disorder)	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Ophthalmoplegia due to neuropathy (disorder)	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Combined paralysis of upgaze and downgaze	Is a	True	Ophthalmoplegia	Inferred relationship	Some
Fisher's syndrome	Is a	True	Ophthalmoplegia	Inferred relationship	Some

Reference Sets