108781007: Topotecan hydrochloride (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Topoisomerase inhibitor\Topotecan hydrochloride

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Alkaloid (substance)\Topotecan hydrochloride

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

173315018 Topotecan hydrochloride en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

604622014 Topotecan hydrochloride (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

2606071000005112 Topotecanhydrochlorid da Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Danish module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Topotecan hydrochloride	Is a	Product containing topotecan (medicinal product)	false	Inferred relationship	Some
Topotecan hydrochloride	Is a	Topotecan (substance)	false	Inferred relationship	Some
Topotecan hydrochloride	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Topoisomerase inhibitor (disposition)	true	Inferred relationship	Some
Topotecan hydrochloride	Is a	Topoisomerase inhibitor	true	Inferred relationship	Some
Topotecan hydrochloride	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Topotecan (substance)	true	Inferred relationship	Some
Topotecan hydrochloride	Is a	Alkaloid (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Topotecan hydrochloride 4mg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Topotecan hydrochloride	Inferred relationship	Some
Topotecan (as topotecan hydrochloride) 4 mg powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Topotecan hydrochloride	Inferred relationship	Some	1
Topotecan (as topotecan hydrochloride) 1 mg powder for solution for injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Topotecan hydrochloride	Inferred relationship	Some	1
Product containing precisely topotecan (as topotecan hydrochloride) 1 milligram/1 each conventional release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Topotecan hydrochloride	Inferred relationship	Some	1
Product containing precisely topotecan (as topotecan hydrochloride) 250 microgram/1 each conventional release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Topotecan hydrochloride	Inferred relationship	Some	1
Topotecan (as topotecan hydrochloride) 1 mg powder for solution for infusion vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Topotecan hydrochloride	Inferred relationship	Some	1
Topotecan (as topotecan hydrochloride) 1 mg powder for solution for infusion and/or injection vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Topotecan hydrochloride	Inferred relationship	Some	1
Product containing precisely topotecan (as topotecan hydrochloride) 4 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Topotecan hydrochloride	Inferred relationship	Some	1
Topotecan (as topotecan hydrochloride) 4 mg powder for solution for infusion vial	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Topotecan hydrochloride	Inferred relationship	Some	1

This concept is not in any reference sets