387050005: Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance)\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)

\Drug or medicament (substance)\Enzyme inhibitor\Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance)\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)
\Drug or medicament (substance)\Analgesic (substance)\Non-opioid analgesic (substance)\Non-steroidal anti-inflammatory agent (substance)\Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Is a	Non-steroidal anti-inflammatory agent (substance)	true	Inferred relationship	Some
Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Has disposition (attribute)	Cyclooxygenase-2 inhibitor	true	Inferred relationship	Some
Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Is a	Substance with prostaglandin-endoperoxide synthase inhibitor mechanism of action (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing etodolac (medicinal product)	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Product containing prostaglandin-endoperoxide synthase isoform 2 inhibitor (product)	Has active ingredient	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some	1
Etodolac 200 mg oral capsule	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Product containing precisely etodolac 300 milligram/1 each conventional release oral capsule (clinical drug)	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
etodolak 600 mg, tablett med modifierad frisättning	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Celecoxib 200 mg oral capsule	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Product containing precisely celecoxib 100 milligram/1 each conventional release oral capsule (clinical drug)	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Product containing celecoxib (medicinal product)	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
etodolak 500 mg, tablett med modifierad frisättning	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
etodolak 400 mg, tablett med modifierad frisättning	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Etodolac 400 mg oral tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Etodolac 500 mg oral tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Product containing valdecoxib (medicinal product)	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Valdecoxib 10 mg oral tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Valdecoxib 20 mg oral tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Nabumetone (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Rofecoxib (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Meloxicam (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Product containing parecoxib (medicinal product)	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Parecoxib 40mg injection (pdr for recon)	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Parecoxib 40mg injection (pdr for recon)+diluent	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Product containing etoricoxib (medicinal product)	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Etoricoxib 60mg tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Etoricoxib 90mg tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Etoricoxib 120mg tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Etoricoxib 60 mg oral tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Etoricoxib 90 mg oral tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Etoricoxib 120 mg oral tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
parecoxib 40 mg, pulver för beredning av injektionsvätska	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
parecoxib 40 mg, pulver för beredning av injektionsvätska + spädningsvätska	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Valdecoxib 40 mg oral tablet	Has active ingredient	False	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Celecoxib	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Etoricoxib (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Parecoxib (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Valdecoxib (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Deracoxib (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Firocoxib (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Lumiracoxib (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Nimesulide (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Parecoxib sodium (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Ketorolac trometamol	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Ketorolac (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Etodolac (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Nepafenac (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Ibuprofen sodium (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Ibuprofen (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Ibuprofen sodium dihydrate (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Ibuprofen lysine (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Dexibuprofen (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Dexketoprofen trometamol (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Dexketoprofen (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Naproxen sodium	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Naproxen (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Fenoprofen (substance)	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Fenoprofen calcium	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some
Alminoprofen	Is a	True	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	Inferred relationship	Some

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3753010015	Prostaglandin-endoperoxide synthase isoform 2 inhibitor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3753726011	Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3753727019	COX-2 inhibitor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
3753728012	PTGS-2 inhibitor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
3753729016	Cyclooxygenase-2 inhibitor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3008961000052113	cox 2-hämmare	sv	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Sweden NRC maintained module (core metadata concept)