Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
T1a1 (IA1): Tumour of uterine cervix with stromal invasion < 3.0 mm in depth and horizontal spread < 7.0 mm |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Blood/lymphatic vessel invasion by tumor present (breast) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
pT3: Tumour more than 4 cm and/or tumour having extraparenchymal extension (major salivary glands) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT4: Tumor perforates the visceral peritoneum or directly invades other organs or structures (small intestine) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T1b (IB): Tumour limited to both ovaries: capsule intact, no tumour on ovarian surface |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Functional status of pancreatic endocrine tumour cannot be assessed |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT4: Tumour invades adjacent structures (stomach) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T2: Tumour > 1 cm but < 4 cm, limited to thyroid |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Local tumour invasion |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
G1: Well differentiated (greater than 95 percent gland forming) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Carcinoma of ovary, stage 1 |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Clinical stage II A |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Scrotal wall involved by direct extension of malignant neoplasm |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Complete obstructing tumour |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3: Tumour involves any of the ipsilateral pleural surfaces plus additional sites as by AJCC 6th Edition definition (thoracic mesothelioma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
National Wilms Tumour Study Group Stage II |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
FIGO CC stage Ib |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
FIGO VC stage III |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T3: Pancreatic tumour extends directly to any of the following: duodenum; bile duct; peripancreatic tissues |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pNX category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pN1: Unilateral metastasis in lymph node(s), 6 cm or less in greatest dimension, above the supraclavicular fossa (nasopharynx) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Prostatic stroma involved by direct extension of malignant neoplasm |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3: Discontinuous tumours in the primary bone site (bone) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT2b: Melanoma 1.01 to 2.0 mm in thickness, with ulceration (melanoma of the skin) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
N1b: Metastasis in multiple regional lymph nodes |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT2: Tumor causing bone erosion or destruction including extension into the hard palate and/or middle nasal meatus, except extension to posterior wall of maxillary sinus and pterygoid plates (maxillary sinus) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Vagina involved by direct extension of malignant neoplasm |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Perineural invasion by tumour present |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT2: Tumour more than 2 cm but not more than 4 cm in greatest dimension without extraparenchymal extension (major salivary glands) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3:Tumour directly invades any of following:chest wall,diaphragm,mediastinal pleura,parietal pericardium;or tumour in main bronchus<2 cm distal to carina(not involving it);or assoc atelectasis or obstructive pneumonitis of whole lung |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
M1b (IVC): All other metastatic sites with two risk factors |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Poorly differentiated histological grade finding |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
No organ AND/OR tissue, other than fallopian tube, macroscopically involved by tumour |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT4: Tumour of any size invades adjacent organ(s), e.g., vagina, urethra, bladder (anal canal) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT1a2 category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Infiltrating ductal carcinoma of breast, stage 4 |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T4a: Breast tumor with extension to chest wall |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Arterial (large vessel) invasion by tumour present |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
4 |
pT2b: Tumour invades deep muscle (outer half) (urinary bladder) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pN2c category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Metastasis stage M4 |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Extra-capsular extension of nodal tumour absent |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
High grade (poorly differentiated to undifferentiated) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumor invasion into tunica albuginea |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Gleason grade score 6 out of 10 |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Lymphoma stage III 1 |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pM1: Distant metastasis (breast) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Circumscribed tumour border |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
T2: Aerodigestive tract tumor invades more than one subsite of hypopharynx or an adjacent site, or measures > 2 cm but < 4 cm in greatest dimension, without fixation of hemilarynx |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
L2 stage |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Epididymis involved by direct extension of malignant neoplasm |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Clinical stage 1 A |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT4: Melanoma greater than 4.0 mm in thickness, with or without ulceration (melanoma of the skin) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Lymphatic (small vessel) invasion by tumor absent |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Clark melanoma level 1 |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pM1a: Metastasis in coeliac lymph nodes (lower thoracic oesophagus) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Microcalcifications in tumour and non-neoplastic tissue present |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Dukes stage D |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Microcalcifications present in malignant neoplasm |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
FIGO CC stage IVB |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Cancer diagnosis based on clinical evidence |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Thyroid TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pN3c category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pM1b: Distant metastasis other than to non-regional lymph nodes and lungs (testis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Modified Dukes stage C2 |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Abnormal radiologic density, nodular |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
T3b (IIIB): Tumour of uterine cervix extends to pelvic wall and/or causes hydronephrosis or nonfunctioning kidney |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT2a (IIA): Tumor without parametrial invasion (TNM category and FIGO stage) (uterine cervix) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT2a: Tumour 10 mm to 16 mm in greatest basal diameter and between 2.5 and 10 mm in maximum height (thickness) without microscopic extraocular extension (ciliary body and choroid) (uveal melanoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T2: Aerodigestive tract tumour causing bone erosion or destruction, except for the posterior antral wall, including extension into hard palate and/or middle nasal meatus |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Any T/any N and M1 (IV): Growth involving one or both ovaries with distant metastasis. (TNM category and FIGO stage) (ovary) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Kidney TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT4: Extraocular tumor extension which includes sites as per American Joint Committee on Cancer 6th Edition definition (retinoblastoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
International neuroblastoma staging system stage 2A |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumour regression finding |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Carcinoma of skin (excluding eyelid, vulva, penis, and melanomas) TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
3 |
pT4 (IVA): Tumour invades mucosa of the bladder or rectum and/or extends beyond the true pelvis (bullous oedema is not sufficient evidence to classify a tumour as T4) (TNM category and FIGO stage) (vagina) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT2: Tumour invades duodenal wall (ampulla of Vater) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Lymphoma stage IIIe |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Modified Dukes stage D |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Pleural invasion by tumour cannot be assessed |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
pT3b (IIIB): Tumour extends to pelvic wall and/or causes hydronephrosis or non-functioning kidney (TNM category and FIGO stage) (uterine cervix) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumour size cannot be assessed |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
T2 (II): Endometrial tumour invades cervix, but does not extend beyond uterus |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Tumour invades beyond pancreatic capsule to adjacent large vessels (endocrine pancreas) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
FIGO CC stage Ib occ |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Gleason Score 2-4: Well differentiated |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT1 (I): Tumour confined to vagina (TNM category and FIGO stage) (vagina) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
N2: Metastasis to ipsilateral axillary lymph node(s) fixed to one another or to other structures |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Epithelial ovarian tumor, International Federation of Gynecology and Obstetrics stage IV |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T1b: Tumor involves both vocal cords |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3: Melanoma 2.01 to 4.0 mm in thickness, with or without ulceration (melanoma of the skin) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Diffuse tumour configuration |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
pT2: Tumour extends to the soft tissues (nasopharynx) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
T2: Ampulla tumor invades duodenal wall |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Pigmented tumour |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Clinical stage I |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Clinical stage IV S |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
pT3: Tumour limited to larynx with vocal cord fixation (larynx, subglottis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
Cancer diagnosis based on specific tumour markers |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
Lymphoma stage IIe |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |