| Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
| pT3: Tumour invades through the muscularis propria into the subserosa or into the nonperitonealized perimuscular tissue (mesentery or retroperitoneum) with extension 2 cm or less (small intestine) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT4: Tumour with intracranial extension, and/or involvement of cranial nerves, infratemporal fossa, hypopharynx, orbit, or masticator space (nasopharynx) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| T1b: Breast tumour >0.5 cm but <= 1 cm in greatest dimension |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Solitary nodule of lung |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Metastasis stage M2 |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| T3: Ampulla tumour invades 2 cm or less into pancreas |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT4a: Tumour invades through thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of the neck including deep intrinsic muscle of the tongue, strap muscles, thyroid, or oesophagus) (larynx, glottis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| T3b: Prostate tumour invades the seminal vesicle(s) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pM1b category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT4b: Tumour invades any of the following: orbital apex, dura, brain, middle cranial fossa, cranial nerves other than maxillary division of trigeminal nerve, nasopharynx, or clivus (nasal cavity and ethmoid sinus) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Ovarian tumour omental implantation not applicable |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT2: Tumour more than 8 cm in greatest dimension (bone) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT1: Tumor restricted to any one subsite, with or without bony invasion (nasal cavity and ethmoid sinus) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pTis: Flat carcinoma in situ (urinary bladder, ureter, renal pelvis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT4b: Tumour invades prevertebral space, encases carotid artery, or invades mediastinal structures (larynx, supraglottis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Gleason Pattern 2 |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Abnormal density |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
3 |
| Venous (large vessel) intramural invasion by tumor present |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
1 |
| GX grade |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
3 |
| Small intestine TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| TX category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Microcalcifications present in ductal carcinoma in situ |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Lymphoma stage finding |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT3b category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Breast TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Non-invasive (epithelial) ovarian tumour omental implants absent |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| T1b (IB): Tumour of uterine cervix with clinically visible lesion confined to the cervix or microscopic lesion greater than T1a2/IA2 |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| T2a: Aerodigestive tract tumour without parapharyngeal extension |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| FIGO EC stage IIIA |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| N1a: Metastasis in ipsilateral cervical lymph node(s) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT3: Tumour invades beyond muscularis into peripelvic fat or renal parenchyma (renal pelvis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT3b: Tumour grossly extends into the renal vein or its segmental (muscle-containing) branches, or vena cava below the diaphragm (kidney) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Dukes stage finding |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Intratumoral/peritumoral lymphocytic response marked |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT2: Tumour more than 2 cm, but not more than 5 cm, in greatest dimension (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| T1c (IC): Tumour limited to one or both tube(s) with extension into or through the tubal serosa; or with malignant cells in ascites or peritoneal washings: FALLOPIAN TUBE: Salpingectomy |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Low grade histologic differentiation |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
| M1: Distant metastasis [includes metastasis to ipsilateral supraclavicular lymph nodes] |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| N1bi: Metastasis in 1 to 3 lymph nodes, any > 0.2 cm and all < 2 cm in greatest dimension |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Tumour metastasis to non-regional lymph nodes present |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Lymphoma stage II |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Tumour location after sectioning cannot be determined |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT1b2 (IB2): Clinically visible lesion more than 4.0 cm in greatest dimension (TNM category and FIGO stage) (uterine cervix) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT3: Tumour more than 4 cm in greatest dimension (lip and oral cavity) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Tumour invades anterior chamber of eye |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Cancer diagnosis based on investigations, without a tissue diagnosis |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT4a: Tumor invades deep extradermal structures (i.e. cartilage, skeletal muscle, or bone) not more than 6mm in thickness (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
3 |
| International Federation of Gynecology and Obstetrics stage finding for vulvar melanoma |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Dukes stage B |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Any T/Any N and M1 (IV): Distant metastasis including presence of malignant cells in pleural fluid or parenchymal hepatic metastasis (TNM category and FIGO stage) (fallopian tube) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Tis: Intratubular germ cell neoplasia (carcinoma in situ, testis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| N3: Metastasis in lymph node(s) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| T2a (IIA): Endometrial tumour with endocervical glandular involvement |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT1: Tumour invades submucosa (colon/rectum) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| T4: Thyroid tumour of any size extending beyond the thyroid capsule |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT3: Tumour confluent with or extending into the ciliary body and/or choroid with scleral extension (iris) (uveal melanoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Tumour present within 1mm of optic disc |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
| No direct extension of malignant neoplasm identified |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Decreased density |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
3 |
| pT1: Tumour invades lamina propria or submucosa (oesophagus) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Pulmonary parenchymal invasion by tumour indeterminate |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
| Insufficient tissue to assess highest pT category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| N0 category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Low grade (well to moderately differentiated) |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT4b: Tumour invades lateral pterygoid muscle, pterygoid plates, lateral nasopharynx, or skull base or encases internal carotid artery (oropharynx) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pM1b: Distant metastasis to bone(s) (prostate) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pN3a: Metastasis in 10 or more axillary lymph nodes (at least one tumour deposit greater than 2.0 mm), or metastasis to infraclavicular lymph nodes (breast) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pN2 (IVB): Bilateral regional lymph node metastasis (pT1-pT4, pM1) (TNM category and FIGO stage) (vulva) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Uveal melanoma TNM finding |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| T2: Aerodigestive tract tumor invades mucosa of >1 adjacent subsite of supraglottis/glottis/region outside supraglottis, (mucosa of base of tongue/vallecula/medial wall of piriform sinus) without fixation of larynx |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| T4: Lung tumour of any size with a malignant pleural effusion |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pN2: Metastasis in the subcarinal lymph node(s) and/or the ipsilateral internal mammary or mediastinal lymph node(s) (thoracic mesothelioma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pM1c category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Tumour stage T4d |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Visceral pleura invasion by tumor absent |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
| G2 grade |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT1a: Tumour limited to the iris (not more than 3 clock hours in size) (iris) (uveal melanoma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| N3: Metastasis in >15 perigastric lymph nodes |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pN1c: Metastasis in more than 7 regional lymph nodes (oesophagus) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT1: Tumour limited to ampulla of Vater or sphincter of Oddi (ampulla of Vater) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pN1 (IIIC): Regional lymph node metastasis (TNM category and FIGO stage) (fallopian tube) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| FIGO CC stage IVA |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Gleason grade score 4 out of 10 |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| L1 stage |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Lymphatic (small vessel) tumour invasion finding |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
| Regression involving less than 75 percent of tumour, present |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pN1a category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Primary site synchronous tumours present |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pM1b (IV): Distant metastasis other than lung (TNM category and FIGO stage) (gestational trophoblast) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT1: Tumour limited to the vocal cord(s) (may involve anterior or posterior commissure) with normal mobility (larynx, glottis) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Heart involved by direct extension of malignant neoplasm |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| Pulmonary parenchymal invasion by tumour absent |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
3 |
| Tumour surgically unresectable |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT3: Tumor more than 5 cm in greatest dimension (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT3: Tumour invades the liver, gallbladder, pancreas, and/or ipsilateral branches of the portal vein (right or left) or hepatic artery (right or left) (extrahepatic bile ducts) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| M1a (IIIC): GTT extends to the lungs with or without genital tract involvement with two risk factors |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| Regression of tumour absent |
Interprets |
True |
Lesion observable |
Inferred relationship |
Some |
2 |
| pMX category |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pT1: Tumour involves ipsilateral parietal pleura, with or without focal involvement of visceral pleura (thoracic mesothelioma) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| T2b (IIB): Tumour of uterine cervix, T2 with parametrial invasion |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |
| pN2: Metastasis in more than one regional lymph node (kidney) |
Interprets |
False |
Lesion observable |
Inferred relationship |
Some |
2 |