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234451005: Acquired von Willebrand disease (disorder)


Status: current, Defined. Date: 31-Jul 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module
1784908015 Acquired von Willebrand syndrome en Synonym Active Initial character case insensitive SNOMED CT core
1784909011 Acquired von Willebrand disease en Synonym Active Initial character case insensitive SNOMED CT core
351278015 Acquired von Willebrand's disease en Synonym Active Initial character case insensitive SNOMED CT core
5156395019 Acquired von Willebrand disease (disorder) en Fully specified name Active Initial character case insensitive SNOMED CT core
5156397010 Acquired von Willebrand disease (VWD) is a rare bleeding disorder marked by the same biological anomalies as those seen in hereditary von Willebrand disease (VWD) but which occurs in association with another underlying pathology, generally in elderly patients without any personal or family history of bleeding anomalies. There are three principle pathogenic mechanisms described which are firstly the presence of autoantibodies (inhibiting or noninhibiting) that form immune complexes with the von Willebrand factor (VWF) leading to rapid clearance of VWF from the circulation. Secondly, absorption of VWF onto malignant cell clones and thirdly the increased proteolysis of high molecular weight VWF multimers under abnormal blood conditions caused by cardiovascular malformations (such as aortic valve stenosis). en Definition Active Case sensitive SNOMED CT core


1 descendants. Search Descendants:

Expanded Value Set


Outbound Relationships Type Target Active Characteristic Refinability Group Values
Acquired von Willebrand's disease Has interpretation Abnormal true Inferred relationship Some 2
Acquired von Willebrand's disease Interprets Haemostatic function true Inferred relationship Some 2
Acquired von Willebrand's disease Finding site Body system structure false Inferred relationship Some
Acquired von Willebrand's disease Has definitional manifestation Haemostatic system finding false Inferred relationship Some
Acquired von Willebrand's disease Is a von Willebrand disorder true Inferred relationship Some
Acquired von Willebrand's disease Finding site Entire haematological system false Inferred relationship Some
Acquired von Willebrand's disease Occurrence Period of life between birth and death true Inferred relationship Some 1
Acquired von Willebrand's disease Is a Acquired coagulation disorder true Inferred relationship Some

Inbound Relationships Type Active Source Characteristic Refinability Group
von Willebrand factor inhibitor disorder Is a True Acquired von Willebrand's disease Inferred relationship Some

Reference Sets

Australian emergency department reference set

Clinical finding foundation reference set

Problem/Diagnosis reference set

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