387381009: méthotrexate (substance)

SNOMED CT Concept\substance\...

\Substance categorized by disposition\Immunomodulator\Antimetabolite (substance)\Antifolate (substance)\Methotrexate (substance)

\Drug or medicament (substance)\Immunologic agent (substance)\Antifolate (substance)\Methotrexate (substance)
\Drug or medicament (substance)\Antineoplastic agent (substance)\Antimetabolite (substance)\Antifolate (substance)\Methotrexate (substance)

\substance catégorisée selon sa structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Pteridine\Methotrexate (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Methotrexate (substance)	est un(e) (attribut)	Antimetabolite (substance)	false	Inferred relationship	Some
Methotrexate (substance)	est un(e) (attribut)	Methotrexate and derivative (substance)	false	Inferred relationship	Some
Methotrexate (substance)	est un(e) (attribut)	Anti-rheumatic agent (substance)	false	Inferred relationship	Some
Methotrexate (substance)	Has disposition (attribute)	Antimetabolite (disposition)	true	Inferred relationship	Some
Methotrexate (substance)	est un(e) (attribut)	Antifolate (substance)	true	Inferred relationship	Some
Methotrexate (substance)	est un(e) (attribut)	Drug allergen (substance)	false	Inferred relationship	Some
Methotrexate (substance)	est un(e) (attribut)	Pteridine	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing only methotrexate (medicinal product)	a pour principe actif (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate only product in oral dose form	a pour principe actif (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
Product containing only methotrexate in parenteral dose form (medicinal product form)	a pour principe actif (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate (as methotrexate sodium) 100 mg/mL solution for injection	Has basis of strength substance (attribute)	True	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 25 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate (as methotrexate sodium) 2.5 mg/mL solution for injection	Has basis of strength substance (attribute)	True	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate skin ulceration (disorder)	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Cirrhosis of liver caused by methotrexate (disorder)	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Cirrhosis of liver caused by methotrexate (disorder)	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	2
Accelerated rheumatoid nodulosis caused by methotrexate (disorder)	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	2
Methotrexate (as methotrexate sodium) 2.5 mg oral tablet	Has basis of strength substance (attribute)	True	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 10 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 15 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 7.5 milligram/1 each conventional release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate (as methotrexate sodium) 20 mg/mL solution for injection	Has basis of strength substance (attribute)	True	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate measurement	élément (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
injection de méthotrexate dans une grossesse tubaire	substance utilisée (attribut)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate poisoning	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Accidental methotrexate poisoning	Causative agent	False	Methotrexate (substance)	Inferred relationship	Some
Intentional methotrexate poisoning	Causative agent	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate poisoning of undetermined intent	Causative agent	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate adverse reaction	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Allergy to methotrexate	Causative agent	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate overdose	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Accidental methotrexate overdose	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Intentional methotrexate overdose	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate overdose of undetermined intent	Causative agent	False	Methotrexate (substance)	Inferred relationship	Some	1
Plasma methotrexate measurement	élément (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	2
Serum methotrexate measurement	élément (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	2
Methotrexate 2.5 mg oral tablet	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 10 mg oral tablet	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 2.5mg/mL injection solution 2mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 25mg/mL injection solution 2mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 25mg/mL injection solution 8mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 25mg/mL injection solution 20mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 25mg/mL injection solution 40mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 25mg/mL injection solution 200mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 100mg/mL injection solution 10mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 100mg/mL injection solution 50mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 12.5mg/mL infusion solution 30mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 12.5mg/mL infusion solution 60mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate excretion measurement (procedure)	élément (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 5 mg oral tablet	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 7.5 mg oral tablet	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 15 mg oral tablet	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate lpf 25mg/mL preservative free injection (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Product containing methotrexate (medicinal product)	a pour principe actif (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate sodium (substance)	est un(e) (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 25mg/mL injection solution 10mL vial (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Neurotoxicity due to methotrexate	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Accidental methotrexate poisoning	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Intentional methotrexate poisoning	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Intravenous injection of Methotrexate	substance utilisée (attribut)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate skin ulceration (disorder)	Causative agent	False	Methotrexate (substance)	Inferred relationship	Some
Intramuscular injection of Methotrexate	substance utilisée (attribut)	False	Methotrexate (substance)	Inferred relationship	Some	1
Intravenous injection of Methotrexate	substance utilisée (attribut)	False	Methotrexate (substance)	Inferred relationship	Some	1
Intravenous injection of Methotrexate	substance utilisée (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
Intramuscular injection of Methotrexate	substance utilisée (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
injection de méthotrexate dans une grossesse tubaire	substance utilisée (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
Measurement of methotrexate in cerebrospinal fluid (procedure)	élément (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	2
Subcutaneous injection of methotrexate (procedure)	substance utilisée (attribut)	False	Methotrexate (substance)	Inferred relationship	Some	1
Subcutaneous injection of methotrexate (procedure)	substance utilisée (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
Allergy to methotrexate	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1
Product containing methotrexate in parenteral dose form (medicinal product form)	a pour principe actif (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate-containing product in oral dose form	a pour principe actif (attribut)	True	Methotrexate (substance)	Inferred relationship	Some	1
Cirrhosis of liver caused by methotrexate (disorder)	Causative agent	False	Methotrexate (substance)	Inferred relationship	Some	3
Methotrexate 2.5 mg oral tablet	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 2.5 mg oral tablet	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 10 mg oral tablet	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 10 mg oral tablet	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 5 mg oral tablet	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 5 mg oral tablet	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 7.5 mg oral tablet	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 7.5 mg oral tablet	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 15 mg oral tablet	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 15 mg oral tablet	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 25mg/mL conventional release solution for injection (product)	a pour principe actif (attribut)	False	Methotrexate (substance)	Inferred relationship	Some
Methotrexate 5 mg oral tablet	Has precise active ingredient	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 2.5 mg oral tablet	Has precise active ingredient	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 7.5 mg oral tablet	Has precise active ingredient	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 10 mg oral tablet	Has precise active ingredient	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate 15 mg oral tablet	Has precise active ingredient	False	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 5 milligram/2 milliliter conventional release solution for injection vial (clinical drug)	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 500 milligram/20 milliliter conventional release solution for injection vial (clinical drug)	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 1 gram/40 milliliter conventional release solution for injection vial (clinical drug)	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 1 gram/10 milliliter conventional release solution for injection vial (clinical drug)	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 5 gram/50 milliliter conventional release solution for injection vial (clinical drug)	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate (as methotrexate sodium) 50 mg/2 mL solution for injection vial	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate (as methotrexate sodium) 200 mg/8 mL solution for injection vial	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Product containing precisely methotrexate (as methotrexate sodium) 5 gram/200 milliliter conventional release solution for injection vial (clinical drug)	Has basis of strength substance (attribute)	False	Methotrexate (substance)	Inferred relationship	Some	1
Methotrexate sodium (substance)	Is modification of (attribute)	True	Methotrexate (substance)	Inferred relationship	Some
Lymphoproliferative disorder caused by methotrexate	Causative agent	True	Methotrexate (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461559012	Methotrexate (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481477014	Methotrexate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1492026011	Amethopterin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
28901000188118	méthotréxate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Common French translation module (core metadata concept)
3756239015	MTX - methotrexate	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
622911000241115	méthotrexate (substance)	fr	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Common French translation module (core metadata concept)
824651000172117	méthotrexate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Common French translation module (core metadata concept)