409159000: Pemetrexed (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Oxidoreductase inhibitor\Dihydrofolate reductase inhibitor\Pemetrexed (substance)
\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Substance with phosphoribosylglycinamide formyltransferase inhibitor mechanism of action (substance)\Pemetrexed (substance)
\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Methyltransferase inhibitor\Thymidylate synthase inhibitor\Pemetrexed (substance)
\Substance categorized by disposition\Immunomodulator\Antimetabolite (substance)\Antifolate (substance)\Pemetrexed (substance)

\Drug or medicament (substance)\Substance with phosphoribosylglycinamide formyltransferase inhibitor mechanism of action (substance)\Pemetrexed (substance)
\Drug or medicament (substance)\Oxidoreductase inhibitor\Dihydrofolate reductase inhibitor\Pemetrexed (substance)
\Drug or medicament (substance)\Immunologic agent (substance)\Antifolate (substance)\Pemetrexed (substance)
\Drug or medicament (substance)\Antineoplastic agent (substance)\Antimetabolite (substance)\Antifolate (substance)\Pemetrexed (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic acid and/or organic acid derivative\Carboxylic acid and/or carboxylic acid derivative (substance)\Carboxylic acid anion (substance)\...

\Amino acid anion (substance)\Alpha amino acid anion (substance)\Glutamate (substance)\Pemetrexed (substance)

\Dicarboxylate\Glutamate (substance)\Pemetrexed (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2004. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Pemetrexed (substance)	Is a	Antifolate (substance)	true	Inferred relationship	Some
Pemetrexed (substance)	Has disposition (attribute)	Antimetabolite (disposition)	true	Inferred relationship	Some
Pemetrexed (substance)	Has disposition (attribute)	Dihydrofolate reductase inhibitor (disposition)	true	Inferred relationship	Some
Pemetrexed (substance)	Is a	Glutamate (substance)	true	Inferred relationship	Some
Pemetrexed (substance)	Has disposition (attribute)	Thymidylate synthase inhibitor (disposition)	true	Inferred relationship	Some
Pemetrexed (substance)	Is a	Substance with phosphoribosylglycinamide formyltransferase inhibitor mechanism of action (substance)	true	Inferred relationship	Some
Pemetrexed (substance)	Is a	Thymidylate synthase inhibitor	true	Inferred relationship	Some
Pemetrexed (substance)	Has disposition (attribute)	Phosphoribosylglycinamide formyltransferase inhibitor (disposition)	true	Inferred relationship	Some
Pemetrexed (substance)	Is a	Dihydrofolate reductase inhibitor	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing precisely pemetrexed (as pemetrexed disodium) 500 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has active ingredient	False	Pemetrexed (substance)	Inferred relationship	Some
Product containing pemetrexed (medicinal product)	Has active ingredient	True	Pemetrexed (substance)	Inferred relationship	Some	1
Product containing precisely pemetrexed (as pemetrexed disodium) 100 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has active ingredient	False	Pemetrexed (substance)	Inferred relationship	Some
Pemetrexed disodium (substance)	Is a	False	Pemetrexed (substance)	Inferred relationship	Some
Pemetrexed only product	Has active ingredient	True	Pemetrexed (substance)	Inferred relationship	Some	1
Pemetrexed disodium (substance)	Is modification of (attribute)	True	Pemetrexed (substance)	Inferred relationship	Some
Product containing precisely pemetrexed (as pemetrexed disodium) 100 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Pemetrexed (substance)	Inferred relationship	Some	1
Product containing precisely pemetrexed (as pemetrexed disodium) 500 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Pemetrexed (substance)	Inferred relationship	Some	1
Pemetrexed-containing product in parenteral dose form	Has active ingredient	True	Pemetrexed (substance)	Inferred relationship	Some	1
Product containing only pemetrexed in parenteral dose form (medicinal product form)	Has active ingredient	True	Pemetrexed (substance)	Inferred relationship	Some	1
Pemetrexed diarginine (substance)	Is modification of (attribute)	True	Pemetrexed (substance)	Inferred relationship	Some
Product containing precisely pemetrexed (as pemetrexed disodium) 100 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	Has basis of strength substance (attribute)	True	Pemetrexed (substance)	Inferred relationship	Some	1
Pemetrexed (as pemetrexed disodium) 500 mg powder for solution for infusion vial	Has basis of strength substance (attribute)	True	Pemetrexed (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
2464610017	Pemetrexed (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2470970016	Pemetrexed	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
65151000195113	Pemetrexed	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
831771000172118	pémétrexed	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
51021000195111	pemetrexed	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module