| Inbound Relationships | Type | Active | Source | Characteristic | Refinability | Group | 
| Lesion size | Is a | True | Lesion observable | Inferred relationship | Some |  | 
| Number of lesions | Is a | True | Lesion observable | Inferred relationship | Some |  | 
| Lesion feature | Is a | True | Lesion observable | Inferred relationship | Some |  | 
| Depth of lesion (observable entity) | Is a | True | Lesion observable | Inferred relationship | Some |  | 
| Abnormal radiologic density, small area | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| pT1: Solitary tumor without vascular invasion (liver, including intrahepatic bile ducts) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Ulcerated tumor configuration | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| T4: Aerodigestive tract tumor invades adjacent structures (pterygoid muscles, mandible, hard palate, deep muscle of tongue, larynx) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| International neuroblastoma pathology classification: Unfavorable histology group, patient less than 1.5 years old, with poorly differentiated or differentiating neuroblastoma (Schwannian stroma-poor) and high mitosis-karyorrhexis index (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| pT3: Multiple tumors more than 5 cm or tumor involving a major branch of the portal or hepatic vein(s) (liver, including intrahepatic bile ducts) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Epithelial ovarian tumor, International Federation of Gynecology and Obstetrics stage IB | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pT2c (IIC): Tumor involves one or both fallopian tubes with pelvic extension with malignant cells in ascites or peritoneal washings (TNM category and FIGO stage) (fallopian tube) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| International Federation of Gynecology and Obstetrics cervical cancer (FIGO CC) stage IIB | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pT2b category | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| T2: Tumor invades muscularis propria | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Lymphoma stage IIIs | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Cancer diagnosis based on death certificate (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Extrahepatic bile ducts TNM finding | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Extraprostatic extension of tumor present, multifocal (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| pT1a (IA): Tumor limited to one ovary; capsule intact, no tumor on ovarian surface. No malignant cells in ascites or peritoneal washings (TNM category and FIGO stage) (ovary) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| T2: Aerodigestive tract tumor > 2 cm but < 4 cm in greatest dimension without extraparenchymal extension | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| International Federation of Gynecology and Obstetrics endometrial cancer stage III | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| High grade (lymphoma) | Interprets | True | Lesion observable | Inferred relationship | Some | 3 | 
| pN category finding | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Tumor invasion of sclera absent (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| T3: Renal tumor extends into major veins or invades the adrenal gland or perinephric tissues but not beyond Gerota's fascia | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| T4: Ampulla tumor invades >2 cm into pancreas and/or into other adjacent organs | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Intergroup rhabdomyosarcoma study post-surgical clinical group IIIB: Localized or locally extensive tumor, gross residual disease after major resection (greater than 50 percent debulking) (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| stade clinique III C | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Tumor invasion finding (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Moderately differentiated histological grade finding (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 3 | 
| Tumor stage T1b2 | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Visceral pleura invasion by tumor indeterminate (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 3 | 
| pT4b category | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Arterial (large vessel) invasion by tumor absent (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 4 | 
| T2b (IIB): Endometrial tumor with cervical stromal invasion | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pT2c: Tumor 10 mm to 16 mm in greatest basal diameter and between 2.5 and 10 mm in maximum height (thickness) with macroscopic extraocular extension (ciliary body and choroid) (uveal melanoma) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| T2: Aerodigestive tract tumor extends to soft tissue of oropharynx and/or nasal fossa | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| International neuroblastoma staging system stage 3 (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Glottis TNM finding | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| International Federation of Gynecology and Obstetrics endometrial cancer stage I B | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pM1a: Distant metastasis to bone marrow (retinoblastoma) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pM1b: Distant metastasis to site other than lung (bone) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| International Federation of Gynecology and Obstetrics cervical cancer (FIGO CC) stage IIA1 | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pN1 (III): Unilateral regional lymph node metastasis (pT1-pT3) (TNM category and FIGO stage) (vulva) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| International Federation of Gynecology and Obstetrics cervical cancer (FIGO CC) stage IB1 | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Major salivary gland TNM finding | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Chest wall involved by direct extension of malignant neoplasm (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| pT4: Tumor more than 16 mm in greatest diameter and/or greater than 10 mm in maximum height (thickness) with extraocular extension (ciliary body and choroid) (uveal melanoma) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| International Federation of Gynecology and Obstetrics vulvar melanoma stage II | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Micropapillary neoplasm pattern (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Adrenal gland involved by direct invasion of renal tumor (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Residual tumor stage R1 | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Breslow measurement - depth greater than 1.75 mm (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Solid, partially encapsulated tumor (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| pT1: Tumor invades lamina propria or submucosa (small intestine) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pT1a: Tumor invades lamina propria (gallbladder) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| stade clinique III A | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Excavated lesion of tumor (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| pT3a (IIIA): Microscopic peritoneal metastasis beyond pelvis (no macroscopic tumor) (TNM category and FIGO stage) (ovary) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Tumor extension finding (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| pT1a: Tumor more than 0.1 cm but not more than 0.5 cm in greatest dimension (breast) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| N3 category | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| L0 stage | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Exophytic (polypoid) tumour configuration | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Marked peritumoral lymphocytic response | Interprets | True | Lesion observable | Inferred relationship | Some | 4 | 
| Node stage N1a | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Ampulla of Vater TNM finding | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pT3: Tumor more than 5 cm in greatest dimension (breast) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| stade clinique I B | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Tumor size cannot be assessed, specimen fragmented (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Lymphoma stage III 2 | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Residual tumor stage RX | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Gleason grade score 5 out of 10 (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Periprostatic fat invasion by tumor not identified (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 3 | 
| pM1 category | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pT1a (IA): Tumor confined to the vulva or vulva and perineum, 2 cm or less in greatest dimension, and with stromal invasion no greater than 1 mm (TNM category and FIGO stage) (vulva) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Perineural invasion by tumor indeterminate (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| T2 (IIC): Trophoblast: gestational trophoblastic tumor extends outside of the uterus but limited to genital structures with two risk factors | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pN3a category | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| T4: Aerodigestive tract tumor invades orbital contents beyond the floor or medial wall including apex and/or any of the following: cribriform plate, base of skull, nasopharynx, sphenoid sinus, frontal sinus | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Annular tumour configuration | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| pN1: Metastasis in 1 to 3 axillary lymph nodes, and/or in internal mammary nodes with microscopic disease detected by sentinel lymph node dissection but not clinically apparent (breast) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| T3: Aerodigestive tract tumor measures > 4 cm in greatest dimension, or with fixation of hemilarynx | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pN1a: Clinically occult (microscopic) metastasis (melanoma of the skin) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pT4: Tumor invades deep extradermal structures (i.e. cartilage, skeletal muscle, or bone) (carcinoma of skin excluding eyelid, vulva, penis, and melanomas) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pN3: Metastasis in four or more regional nodes, or matted metastatic nodes, or in-transit metastasis or satellite(s) with metastasis in regional node(s) (melanoma of the skin) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pN0: No regional lymph node metastasis histologically (i.e., none greater than 0.2 mm), no additional examination for isolated tumor cells (breast) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pN3: Metastasis in a lymph node(s), more than 6 cm in dimension, and/or to supraclavicular fossa (nasopharynx) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pT4a: Tumor of any size with extension to chest wall, not including pectoralis muscle (breast) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pN1a: Metastasis in single regional lymph node (exocrine pancreas) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Carcinoma of ovary, stage 3 | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Tumor invades vitreous (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| pT3 and/or N1 (III): Tumor involves one or both ovaries with microscopically confirmed peritoneal metastasis outside the pelvis (including liver capsule metastasis) and/or regional lymph node metastasis (TNM category and FIGO stage) (ovary) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| Modified Dukes stage A | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Intratumoral/peritumoral lymphocytic response absent (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Intergroup rhabdomyosarcoma study post-surgical clinical group IB: localized tumor, infiltrating beyond site of origin, completely resected (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Thymic epithelial neoplasm stage finding (finding) | Interprets | True | Lesion observable | Inferred relationship | Some | 2 | 
| Lung TNM finding | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| pT1b: Tumor invades submucosa (esophagus) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 | 
| No pT1 category, insufficient tissue (prostate) | Interprets | False | Lesion observable | Inferred relationship | Some | 2 |