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234451005: Acquired von Willebrand disease (disorder)


Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module
351278015 Acquired von Willebrand's disease en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core
1784908015 Acquired von Willebrand syndrome en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core
1784909011 Acquired von Willebrand disease en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core
5156395019 Acquired von Willebrand disease (disorder) en Fully specified name Active Only initial character case insensitive (core metadata concept) SNOMED CT core
5156397010 Acquired von Willebrand disease (VWD) is a rare bleeding disorder marked by the same biological anomalies as those seen in hereditary von Willebrand disease (VWD) but which occurs in association with another underlying pathology, generally in elderly patients without any personal or family history of bleeding anomalies. There are three principle pathogenic mechanisms described which are firstly the presence of autoantibodies (inhibiting or noninhibiting) that form immune complexes with the von Willebrand factor (VWF) leading to rapid clearance of VWF from the circulation. Secondly, absorption of VWF onto malignant cell clones and thirdly the increased proteolysis of high molecular weight VWF multimers under abnormal blood conditions caused by cardiovascular malformations (such as aortic valve stenosis). en Definition Active Entire term case sensitive (core metadata concept) SNOMED CT core
4995621000241112 maladie de von Willebrand acquise fr Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module


1 descendants. Search Descendants:

Expanded Value Set


Outbound Relationships Type Target Active Characteristic Refinability Group Values
Acquired von Willebrand disease Is a von Willebrand disorder true Inferred relationship Some
Acquired von Willebrand disease Finding site Entire hematological system (body structure) false Inferred relationship Some
Acquired von Willebrand disease Finding site Body system structure false Inferred relationship Some
Acquired von Willebrand disease Has definitional manifestation Hemostatic system finding false Inferred relationship Some
Acquired von Willebrand disease Occurrence Period of life beginning after birth and ending before death (qualifier value) true Inferred relationship Some 1
Acquired von Willebrand disease Is a Acquired coagulation disorder true Inferred relationship Some
Acquired von Willebrand disease Has interpretation Abnormal true Inferred relationship Some 2
Acquired von Willebrand disease Interprets Hemostatic function true Inferred relationship Some 2

Inbound Relationships Type Active Source Characteristic Refinability Group
von Willebrand factor inhibitor disorder Is a True Acquired von Willebrand disease Inferred relationship Some

This concept is not in any reference sets

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