| Inbound Relationships | Type | Active | Source | Characteristic | Refinability | Group | 
| NK cell origin | Is a | True | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| T-cell origin | Is a | True | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| No vascular invasion by tumor | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Vascular invasion by tumor is indeterminate | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Residual tumor stage (observable entity) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Recurrent neoplasm (disorder) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| B-cell origin | Is a | True | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Non T- non B-cell origin | Is a | True | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Microinvasive tumor | Is a | True | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Grade not determined | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Vascular invasion by tumor | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Cell type not determined | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Moderately differentiated | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Large unstained cells | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Margin involvement indeterminate | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Margins cannot be assessed | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Surgical distal margin involved by tumor (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| G3-4: Poorly differentiated/undifferentiated | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Small vessel invasion by tumor absent (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Blood/lymphatic (small) vessel invasion by tumor | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Perineural invasion by tumor present (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Venous (large vessel) invasion by tumor present (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Venous (large vessel) invasion by tumor absent (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Venous (large vessel) invasion by tumor indeterminate (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Venous invasion cannot be assessed | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Venous vessels outside tumor uninvolved by tumor (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Venous vessels outside tumor indeterminate for tumor involvement | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Mild to moderate peritumoral lymphocytic response | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Marked peritumoral lymphocytic response | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Low grade (lymphoma) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| High grade (lymphoma) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Greater than 4 mitoses per high power field (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| < 4 mitoses/high power field | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Breast tubule formation, majority of tumor greater than 75 percent (score = 1) (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Breast tubule formation, moderate 10 percent to 75 percent (score = 2) (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Breast tubule formation, minimal less than 10 percent (score = 3) (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| DCIS nuclear pleomorphism, grade 1: monotonous nuclei, 1.5 - 2.0 RBC diameters, with finely dispersed chromatin and only occasional nucleoli | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| DCIS nuclear pleomorphism, grade 2: neither nuclear grade 1 nor nuclear grade 3 | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| DCIS nuclear pleomorphism, grade 3: Markedly pleomorphic nuclei, usually >2.5 RBC diameters, with coarse chromatin and multiple nucleoli | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Less than 10 mitoses per 10 HPF (score = 1) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| 10-20 mitoses per 10 HPF (score = 2) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Greater than 20 mitoses per 10 HPF (score = 3) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| 0-5 mitoses per 10 HPF (score = 1) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| 6-10 mitoses per 10 HPF (score = 2) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Greater than 10 mitoses per 10 HPF (score = 3) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Nottingham Combined Grade I: 3-5 points (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Nottingham Combined Grade II: 6-7 points | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Nottingham Combined Grade III: 8-9 points | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Tumor invasion cannot be assessed | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| No tumor invasion | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| No tumor invasion of adjacent tissue | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Perineural invasion by tumor absent (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Presence of direct invasion by malignant neoplasm (observable entity) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| No peritumoral lymphocytic response | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Surgical margin involved by tumor (finding) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Tumor border behavior | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Tumor configuration | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Surgical margin free of tumor | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Histologic configuration of number of tumors | Is a | True | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Histological grades | Is a | True | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Breast tubule formation | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Nottingham combined grade of primary malignant neoplasm of breast (observable entity) | Is a | False | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  | 
| Histologic architectural pattern (qualifier value) | Is a | True | Histologic grading differentiation AND/OR behavior | Inferred relationship | Some |  |