900000000000526001: REPLACED BY association reference set (foundation metadata concept)

SNOMED CT Concept\SNOMED CT Model Component\Foundation metadata concept (foundation metadata concept)\Reference set\Association type\Historical association reference set (foundation metadata concept)\REPLACED BY association reference set (foundation metadata concept)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT model component module (core metadata concept)

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
REPLACED BY association reference set (foundation metadata concept)	Is a	Historical association reference set (foundation metadata concept)	true	Inferred relationship	Some

Members	targetComponentId
pN1c: Metastasis in 1 to 3 axillary lymph nodes and in internal mammary lymph nodes with microscopic disease detected by sentinel lymph node dissection but not clinically apparent (breast)	American Joint Committee on Cancer pN1c (qualifier value)
pN1c: Metastasis in more than 7 regional lymph nodes (esophagus)	American Joint Committee on Cancer pN1c (qualifier value)
pN1mi category	American Joint Committee on Cancer pN1mi (qualifier value)
pN1mi(i+): Micrometastasis detected only by immunohistochemistry (breast)	American Joint Committee on Cancer pN1mi (qualifier value)
pN1mi: Micrometastasis (greater than 0.2 mm, none greater than 2.0 mm) (breast)	American Joint Committee on Cancer pN1mi (qualifier value)
pN2 (IVA): Bilateral regional lymph node metastasis (pT1-pT4) (TNM category and FIGO stage) (vulva)	pN2
pN2 (IVB): Bilateral regional lymph node metastasis (pT1-pT4, pM1) (TNM category and FIGO stage) (vulva)	pN2
stade pN2	pN2
pN2: Bilateral metastasis in lymph node(s), 6 cm or less in greatest dimension, above the supraclavicular fossa (nasopharynx)	pN2
pN2: Bilateral regional lymph node metastasis (vulva)	pN2
pN2: Metastasis in 2 to 3 regional nodes or intralymphatic regional metastasis without nodal metastasis (melanoma of the skin)	pN2
pN2: Metastasis in 4 or more regional lymph nodes (colon/rectum)	pN2
pN2: Metastasis in 4 to 9 axillary lymph nodes, or in clinically apparent internal mammary lymph nodes in the absence of axillary lymph node metastasis (breast)	pN2
pN2: Metastasis in 7 to 15 regional (perigastric) lymph nodes (stomach)	pN2
pN2: Metastasis in a single lymph node, more than 2 cm but not more than 5 cm in greatest dimension; or multiple lymph nodes, none more than 5 cm in greatest dimension (urinary bladder, ureter, renal pelvis)	pN2
pN2: Metastasis in more than one regional lymph node (kidney)	pN2
pN2: Metastasis in the subcarinal lymph node(s) and/or the ipsilateral internal mammary or mediastinal lymph node(s) (thoracic mesothelioma)	pN2
pN2: Metastasis in unilateral internal iliac AND/OR inguinal lymph node(s) (anal canal)	pN2
pN2: Metastasis to ipsilateral mediastinal and/or subcarinal lymph nodes(s) (lung)	pN2
pN2: Metastasis with a lymph node mass more than 2 cm but not more than 5 cm in greatest dimension; or more than 5 nodes positive, none more than 5 cm; or evidence of extranodal extension of tumor (testis)	pN2
pN2a category	pN2a
pN2a: Clinically occult (microscopic) metastasis (melanoma of the skin)	pN2a
pN2a: Metastasis in 4 to 9 axillary lymph nodes (at least one tumor deposit greater than 2.0 mm) (breast)	pN2a
pN2a: Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension (upper aerodigestive tract)	pN2a
pN2b category	American Joint Committee on Cancer pN2b (qualifier value)
pN2b: Clinically apparent (macroscopic) metastasis (melanoma of the skin)	American Joint Committee on Cancer pN2b (qualifier value)
pN2b: Metastasis in clinically apparent internal mammary lymph nodes in the absence of axillary lymph node metastasis (breast)	American Joint Committee on Cancer pN2b (qualifier value)
pN2b: Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension (upper aerodigestive tract)	American Joint Committee on Cancer pN2b (qualifier value)
pN2c category	American Joint Committee on Cancer pN2c (qualifier value)
pN2c: Metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension (upper aerodigestive tract)	American Joint Committee on Cancer pN2c (qualifier value)
pN2c: Satellite or in-transit metastasis without nodal metastasis (melanoma of the skin)	American Joint Committee on Cancer pN2c (qualifier value)
stade pN3	American Joint Committee on Cancer pN3 (qualifier value)
pN3: Metastasis in a lymph node(s), more than 6 cm in dimension, and/or to supraclavicular fossa (nasopharynx)	American Joint Committee on Cancer pN3 (qualifier value)
pN3: Metastasis in a lymph node, more than 5 cm in greatest dimension (urinary bladder, ureter, renal pelvis)	American Joint Committee on Cancer pN3 (qualifier value)
pN3: Metastasis in a lymph node, more than 6 cm in greatest dimension (upper aerodigestive tract)	American Joint Committee on Cancer pN3 (qualifier value)
pN3: Metastasis in four or more regional nodes, or matted metastatic nodes, or in-transit metastasis or satellite(s) with metastasis in regional node(s) (melanoma of the skin)	American Joint Committee on Cancer pN3 (qualifier value)
pN3: Metastasis in more than 15 regional (perigastric) lymph nodes (stomach)	American Joint Committee on Cancer pN3 (qualifier value)
pN3: Metastasis in perirectal and inguinal lymph nodes AND/OR bilateral internal iliac AND/OR inguinal lymph nodes (anal canal)	American Joint Committee on Cancer pN3 (qualifier value)
pN3: Metastasis in the contralateral mediastinal, internal mammary, or hilar lymph node(s), and/or the ipsilateral or contralateral supraclavicular or scalene lymph node(s) (thoracic mesothelioma)	American Joint Committee on Cancer pN3 (qualifier value)
pN3: Metastasis to contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph nodes(s) (lung)	American Joint Committee on Cancer pN3 (qualifier value)
pN3: Metastasis with a lymph node mass more than 5 cm in greatest dimension (testis)	American Joint Committee on Cancer pN3 (qualifier value)
pN3a category	American Joint Committee on Cancer pN3a (qualifier value)
pN3a: Metastasis in 10 or more axillary lymph nodes (at least one tumor deposit greater than 2.0 mm), or metastasis to infraclavicular lymph nodes (breast)	American Joint Committee on Cancer pN3a (qualifier value)
pN3a: Metastasis in a lymph node(s), more than 6 cm in dimension (nasopharynx)	American Joint Committee on Cancer pN3a (qualifier value)
pN3b category	American Joint Committee on Cancer pN3b (qualifier value)
pN3b: Metastasis in lymph node(s) residing wholly or in part in the supraclavicular fossa (nasopharynx)	American Joint Committee on Cancer pN3b (qualifier value)
pN3b: Tumor of breast with metastasis as per American Joint Committee on Cancer 6th Edition definition (breast)	American Joint Committee on Cancer pN3b (qualifier value)
pN3c category	pN3c
pN3c: Metastasis in ipsilateral supraclavicular lymph nodes (breast)	pN3c
stade pNX	American Joint Committee on Cancer pNX (qualifier value)
pNX: Regional lymph nodes cannot be assessed (e.g., previously removed, or not removed for pathologic study) (breast)	American Joint Committee on Cancer pNX (qualifier value)
pT category finding	American Joint Committee on Cancer pathological T category allowable value (qualifier value)
pT category not identified	pTX
stade pT0	American Joint Committee on Cancer pT0 (qualifier value)
pT0: No evidence of primary tumor (breast)	American Joint Committee on Cancer pT0 (qualifier value)
pT1 (I): Cervical carcinoma confined to uterus (extension to corpus should be disregarded) (TNM category and FIGO stage) (uterine cervix)	American Joint Committee on Cancer pT1 (qualifier value)
pT1 (I): Tumor confined to corpus uteri (TNM category and FIGO stage) (corpus uteri)	American Joint Committee on Cancer pT1 (qualifier value)
pT1 (I): Tumor confined to the vulva or vulva and perineum, 2 cm or less in greatest dimension (TNM category and FIGO stage) (vulva)	American Joint Committee on Cancer pT1 (qualifier value)
pT1 (I): Tumor confined to uterus (TNM category and FIGO stage) (gestational trophoblast)	American Joint Committee on Cancer pT1 (qualifier value)
pT1 (I): Tumor confined to vagina (TNM category and FIGO stage) (vagina)	American Joint Committee on Cancer pT1 (qualifier value)
pT1 (I): Tumor limited to ovaries (one or both) (TNM category and FIGO stage) (ovary)	American Joint Committee on Cancer pT1 (qualifier value)
pT1 (I): Tumor limited to the fallopian tube(s) (TNM category and FIGO stage) (fallopian tube)	American Joint Committee on Cancer pT1 (qualifier value)
stade pT1	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Melanoma 1.0 mm or less in thickness, with or without ulceration (melanoma of the skin)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Solitary tumor without vascular invasion (liver, including intrahepatic bile ducts)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 10 mm or less in greatest diameter and 2.5 mm or less in greatest height (thickness) (ciliary body and choroid) (uveal melanoma)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 2 cm or less in greatest dimension (anal canal)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 2 cm or less in greatest dimension (breast)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 2 cm or less in greatest dimension (carcinoma of skin excluding eyelid, vulva, penis, and melanomas)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 2 cm or less in greatest dimension	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 2 cm or less in greatest dimension (lip and oral cavity)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 2 cm or less in greatest dimension (oropharynx)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 2 cm or less in greatest dimension limited to the thyroid (thyroid)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 2 cm or less in greatest dimension without extraparenchymal extension (major salivary glands)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 3 cm or less in greatest dimension, surrounded by lung or visceral pleura, without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus) (lung)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 5 cm or less in greatest dimension (extraosseous primitive neuroectodermal tumor/Ewing's sarcoma)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 7 cm or less in greatest dimension, limited to the kidney (kidney)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 8 cm or less in greatest dimension (bone)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor 8 cm or less in greatest dimension (osseous primitive neuroectodermal tumor/Ewing's sarcoma)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor confined to the bile duct histologically (extrahepatic bile ducts)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor confined to the nasopharynx (nasopharynx)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor confined to the retina, vitreous, or subretinal space. No optic nerve or choroidal invasion (retinoblastoma)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor invades lamina propria or muscle layer (gallbladder)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor invades lamina propria or submucosa (esophagus)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor invades lamina propria or submucosa (small intestine)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor invades lamina propria or submucosa (stomach)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor invades subepithelial connective tissue (urinary bladder, ureter, renal pelvis)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor invades submucosa (appendix)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor invades submucosa (colon/rectum)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor involves ipsilateral parietal pleura, with or without focal involvement of visceral pleura (thoracic mesothelioma)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor limited to ampulla of Vater or sphincter of Oddi (ampulla of Vater)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor limited to one subsite of hypopharynx and 2 cm or less in greatest dimension (hypopharynx)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor limited to one subsite of supraglottis with normal vocal cord mobility (larynx, supraglottis)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor limited to the iris (iris) (uveal melanoma)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor limited to the maxillary sinus mucosa with no erosion or destruction of bone (maxillary sinus)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor limited to the pancreas, 2 cm or less in greatest dimension (exocrine pancreas)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor limited to the subglottis (larynx, subglottis)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor limited to the testis and epididymis without vascular/lymphatic invasion; tumor may invade into the tunica albuginea but not the tunica vaginalis (testis)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor limited to the vocal cord(s) (may involve anterior or posterior commissure) with normal mobility (larynx, glottis)	American Joint Committee on Cancer pT1 (qualifier value)
pT1: Tumor restricted to any one subsite, with or without bony invasion (nasal cavity and ethmoid sinus)	American Joint Committee on Cancer pT1 (qualifier value)
pT1a (IA): Invasive carcinoma diagnosed only by microscopy. All macroscopically visible lesions (even with superficial invasion) are pT1b/IB (TNM category and FIGO stage) (uterine cervix)	pT1a

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Reference Sets

Reference set descriptor

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Id	Description	Lang	Type	Status	Case?	Module
900000000001156010	REPLACED BY association reference set (foundation metadata concept)	en	Fully specified name	Active	Entire term case sensitive (core metadata concept)	SNOMED CT model component module (core metadata concept)
900000000001157018	REPLACED BY association reference set	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT model component module (core metadata concept)
7237811000172118	referentieset voor associaties betreffende vervangende concepten	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)