784176007: Substance with human epidermal growth factor receptor 2 inhibitor mechanism of action (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Epidermal growth factor receptor inhibitor\Human epidermal growth factor receptor 2 inhibitor

\Drug or medicament (substance)\Antineoplastic agent (substance)\Epidermal growth factor receptor inhibitor\Human epidermal growth factor receptor 2 inhibitor

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2019. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3761513018 HER2 (Human epidermal growth factor receptor 2) inhibitor en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

3761514012 Human epidermal growth factor receptor 2 inhibitor en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3761515013 Substance with human epidermal growth factor receptor 2 inhibitor mechanism of action (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

13706461000172113 human epidermal growth factor receptor 2 inhibitor nl Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Belgian module (core metadata concept)

13706471000172116 HER2-remmer nl Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) Belgian module (core metadata concept)

13706481000172118 remmer van humane epidermale groeifactorreceptor 2 nl Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) Belgian module (core metadata concept)

13706491000172115 remmer van HER2 nl Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) Belgian module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Human epidermal growth factor receptor 2 inhibitor	Is a	Protein-tyrosine kinase inhibitor	false	Inferred relationship	Some
Human epidermal growth factor receptor 2 inhibitor	Has disposition (attribute)	Human epidermal growth factor receptor 2 inhibitor	true	Inferred relationship	Some
Human epidermal growth factor receptor 2 inhibitor	Is a	Epidermal growth factor receptor inhibitor	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Trastuzumab (substance)	Is a	True	Human epidermal growth factor receptor 2 inhibitor	Inferred relationship	Some
Pertuzumab	Is a	True	Human epidermal growth factor receptor 2 inhibitor	Inferred relationship	Some
Trastuzumab emtansine	Is a	True	Human epidermal growth factor receptor 2 inhibitor	Inferred relationship	Some
Trastuzumab deruxtecan	Is a	True	Human epidermal growth factor receptor 2 inhibitor	Inferred relationship	Some
Margetuximab (substance)	Is a	True	Human epidermal growth factor receptor 2 inhibitor	Inferred relationship	Some
Receptor tyrosine-protein kinase erbB-2 inhibitor therapy (procedure)	Direct substance	True	Human epidermal growth factor receptor 2 inhibitor	Inferred relationship	Some	1
Lapatinib (substance)	Is a	True	Human epidermal growth factor receptor 2 inhibitor	Inferred relationship	Some

Reference Sets

Belgian subset for AllergyIntolerance, causative agent, drug