387003001: Trastuzumab (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Epidermal growth factor receptor inhibitor\Human epidermal growth factor receptor 2 inhibitor\Trastuzumab (substance)
\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Enzyme inhibitor protein\Trastuzumab (substance)
\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Trastuzumab (substance)

\Drug or medicament (substance)\Immunosuppressant (substance)\Trastuzumab (substance)
\Drug or medicament (substance)\Antineoplastic agent (substance)\Epidermal growth factor receptor inhibitor\Human epidermal growth factor receptor 2 inhibitor\Trastuzumab (substance)
\Drug or medicament (substance)\Enzyme inhibitor protein\Trastuzumab (substance)
\Drug or medicament (substance)\Monoclonal antibody\Trastuzumab (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide (substance)\Protein\...

\Enzyme inhibitor protein\Trastuzumab (substance)

\Antibody\Monoclonal antibody\Trastuzumab (substance)

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide (substance)\Protein\...

\Enzyme inhibitor protein\Trastuzumab (substance)

\Antibody\Monoclonal antibody\Trastuzumab (substance)

\Biological substance\Immunologic substance\Antibody\Monoclonal antibody\Trastuzumab (substance)
\Biological substance\Polypeptide (substance)\Protein\Enzyme inhibitor protein\Trastuzumab (substance)
\Biological substance\Polypeptide (substance)\Protein\Antibody\Monoclonal antibody\Trastuzumab (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Trastuzumab (substance)	Is a	Antineoplastic agent (substance)	false	Inferred relationship	Some
Trastuzumab (substance)	Is a	Murine-human monoclonal immunoglobulin G antibody	false	Inferred relationship	Some
Trastuzumab (substance)	Has disposition (attribute)	Murine-human monoclonal immunoglobulin G antibody	false	Inferred relationship	Some
Trastuzumab (substance)	Has disposition (attribute)	Immunomodulator (disposition)	true	Inferred relationship	Some
Trastuzumab (substance)	Is a	Human epidermal growth factor receptor 2 inhibitor	true	Inferred relationship	Some
Trastuzumab (substance)	Has disposition (attribute)	Human epidermal growth factor receptor 2 inhibitor	true	Inferred relationship	Some
Trastuzumab (substance)	Is a	Enzyme inhibitor protein	true	Inferred relationship	Some
Trastuzumab (substance)	Is a	Immunosuppressant (substance)	true	Inferred relationship	Some
Trastuzumab (substance)	Is a	Monoclonal antibody	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing trastuzumab (medicinal product)	Has active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 150 mg powder for solution for injection vial	Has active ingredient	False	Trastuzumab (substance)	Inferred relationship	Some
Trastuzumab 440 mg powder for solution for injection vial	Has active ingredient	False	Trastuzumab (substance)	Inferred relationship	Some
Adverse reaction to trastuzumab administered by infusion	Causative agent	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab emtansine	Is a	False	Trastuzumab (substance)	Inferred relationship	Some
Product containing trastuzumab in parenteral dose form (medicinal product form)	Has active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 150 mg powder for solution for injection vial	Has basis of strength substance (attribute)	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 150 mg powder for solution for injection vial	Has precise active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing only trastuzumab (medicinal product)	Has active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab only product in parenteral dose form	Has active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab emtansine	Is modification of (attribute)	False	Trastuzumab (substance)	Inferred relationship	Some
Trastuzumab 440 mg powder for solution for injection vial	Has basis of strength substance (attribute)	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 440 mg powder for solution for injection vial	Has precise active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab deruxtecan	Is modification of (attribute)	False	Trastuzumab (substance)	Inferred relationship	Some
Product containing precisely trastuzumab 120 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely trastuzumab 120 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely trastuzumab 60 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely trastuzumab 60 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely trastuzumab 420 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	Has precise active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Product containing precisely trastuzumab 420 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	Has basis of strength substance (attribute)	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 60 mg powder for solution for infusion vial	Has precise active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 60 mg powder for solution for infusion vial	Has basis of strength substance (attribute)	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 60 mg powder for solution for infusion and/or injection vial	Has precise active ingredient	True	Trastuzumab (substance)	Inferred relationship	Some	1
Trastuzumab 60 mg powder for solution for infusion and/or injection vial	Has basis of strength substance (attribute)	True	Trastuzumab (substance)	Inferred relationship	Some	1

Reference Sets

Belgian subset for AllergyIntolerance, causative agent, drug

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Id	Description	Lang	Type	Status	Case?	Module
1461181011	Trastuzumab (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481117012	Trastuzumab	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
847121000172110	trastuzumab	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)
847131000172113	trastuzumab	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	Belgian module (core metadata concept)