56564003: BCR-ABL-fusie-eiwit (substantie)

SNOMED CT Concept\Substance\...

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide (substance)\Protein\Oncogene protein\Fusion protein BCR-ABL

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide (substance)\Protein\Oncogene protein\Fusion protein BCR-ABL

\Biological substance\Polypeptide (substance)\Protein\Oncogene protein\Fusion protein BCR-ABL

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

94070011 Fusion protein BCR-ABL en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core

94071010 BCR-ABL protein en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

795090018 Fusion protein BCR-ABL (substance) en Fully specified name Active Only initial character case insensitive (core metadata concept) SNOMED CT core

13062221000146112 BCR-ABL-fusie-eiwit nl Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Netherlands NRC maintained module (core metadata concept)

13062231000146114 BCR-ABL-eiwit nl Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Netherlands NRC maintained module (core metadata concept)

13062241000146118 BCR-ABL-fusie-eiwit (substantie) nl Fully specified name Active Entire term case sensitive (core metadata concept) SNOMED CT Netherlands NRC maintained module (core metadata concept)

13062251000146115 fusie-eiwit BCR-ABL nl Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT Netherlands NRC maintained module (core metadata concept)

13062591000146112 Eiwitten die ontstaan door translocatie (uitwisseling) van chromosomen 9 en 22. Hierdoor ontstaat het zogenaamde philadelphiachromosoom. Bij chromosoom 9 treedt de breuk op bij het ABL-gen en bij chromosoom 22 bij het BCR-gen. Door deze fusie ontstaat het BCR-ABL-gen op chromosoom 22, dat verantwoordelijk is voor de productie van BCR-ABL-eiwit. Dit eiwit veroorzaakt ongeremde groei van witte bloedcellen bij chronische myeloïde leukemie (CML) en wordt hierom gebruikt als tumormarker. nl Definition Active Entire term case sensitive (core metadata concept) SNOMED CT Netherlands NRC maintained module (core metadata concept)

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Fusion protein BCR-ABL	Is a	Oncogene protein	true	Inferred relationship	Some

Inbound Relationships

Type

Active

Source

Characteristic

Refinability

Group

This concept is not in any reference sets