387152000: alteplase (substantie)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme activator\Plasminogen activator\Alteplase (substance)
\Substance categorized by disposition\Enzyme\Hydrolase\Peptide hydrolase\Plasminogen activator\Alteplase (substance)

\Drug or medicament (substance)\Hematologic agent (substance)\Thrombolytic agent (substance)\Plasminogen activator\Alteplase (substance)
\Drug or medicament (substance)\Cardiovascular agent (substance)\Thrombolytic agent (substance)\Plasminogen activator\Alteplase (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide (substance)\Protein\Alteplase (substance)

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide (substance)\Protein\Alteplase (substance)

\Biological substance\Polypeptide (substance)\Protein\Alteplase (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Alteplase (substance)	Is a	Tissue plasminogen activator	false	Inferred relationship	Some
Alteplase (substance)	Is a	Substance with plasminogen activator mechanism of action	false	Inferred relationship	Some
Alteplase (substance)	Has disposition (attribute)	Plasminogen activator (disposition)	true	Inferred relationship	Some
Alteplase (substance)	Is a	Plasminogen activator	true	Inferred relationship	Some
Alteplase (substance)	Is a	Hydrolase	false	Inferred relationship	Some
Alteplase (substance)	Is a	Protein	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing alteplase (medicinal product)	Has active ingredient	True	Alteplase (substance)	Inferred relationship	Some	1
Alteplase adverse reaction	Causative agent	True	Alteplase (substance)	Inferred relationship	Some	1
Allergy to alteplase	Causative agent	False	Alteplase (substance)	Inferred relationship	Some
Alteplase 50mg powder and solvent for injection solution vial	Has active ingredient	False	Alteplase (substance)	Inferred relationship	Some
Alteplase 20mg powder and solvent for injection solution vial	Has active ingredient	False	Alteplase (substance)	Inferred relationship	Some
Alteplase 10mg powder and solvent for injection solution vial	Has active ingredient	False	Alteplase (substance)	Inferred relationship	Some
Alteplase 100mg powder	Has active ingredient	False	Alteplase (substance)	Inferred relationship	Some
Alteplase 1mg injection solution 1mL vial	Has active ingredient	False	Alteplase (substance)	Inferred relationship	Some
Continuous infusion of alteplase	Direct substance	False	Alteplase (substance)	Inferred relationship	Some	1
Continuous infusion of alteplase	Direct substance	True	Alteplase (substance)	Inferred relationship	Some	1
Allergy to alteplase	Causative agent	True	Alteplase (substance)	Inferred relationship	Some	1
Product containing precisely alteplase 50 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Alteplase (substance)	Inferred relationship	Some	1
Product containing precisely alteplase 50 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Alteplase (substance)	Inferred relationship	Some	1
Alteplase 10 mg powder for solution for injection vial	Has precise active ingredient	True	Alteplase (substance)	Inferred relationship	Some	1
Alteplase 10 mg powder for solution for injection vial	Has basis of strength substance (attribute)	True	Alteplase (substance)	Inferred relationship	Some	1
Product containing precisely alteplase 20 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Alteplase (substance)	Inferred relationship	Some	1
Product containing precisely alteplase 20 milligram/1 vial powder for conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Alteplase (substance)	Inferred relationship	Some	1
Product containing alteplase in parenteral dose form (medicinal product form)	Has active ingredient	True	Alteplase (substance)	Inferred relationship	Some	1
Product containing only alteplase (medicinal product)	Has active ingredient	True	Alteplase (substance)	Inferred relationship	Some	1
Product containing only alteplase in parenteral dose form (medicinal product form)	Has active ingredient	True	Alteplase (substance)	Inferred relationship	Some	1
Product containing precisely alteplase 2 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	Has precise active ingredient	True	Alteplase (substance)	Inferred relationship	Some	1
Product containing precisely alteplase 2 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	Has basis of strength substance (attribute)	True	Alteplase (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461330011	Alteplase (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481260011	Alteplase	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3635509011	Tissue-type plasminogen activator	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3635514010	rt-PA - Tissue-type plasminogen activator	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
4527451000146113	alteplase	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4527471000146117	alteplase (substantie)	nl	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4834951000146114	rtPA	nl	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
10392911000146112	recombinant-weefselplasminogeenactivator	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)