386975001: tacrolimus (substantie)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Hydrolase inhibitor\Calcineurin inhibitor\Tacrolimus (substance)
\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Tacrolimus (substance)

\Drug or medicament (substance)\Calcineurin inhibitor\Tacrolimus (substance)
\Drug or medicament (substance)\Immunosuppressant (substance)\Tacrolimus (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Lactone (substance)\Macrolide (substance)\Tacrolimus (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tacrolimus (substance)	Is a	Immunosuppressant (substance)	true	Inferred relationship	Some
Tacrolimus (substance)	Is a	allergeen	false	Inferred relationship	Some
Tacrolimus (substance)	Is a	allergeen van geneesmiddel (substantie)	false	Inferred relationship	Some
Tacrolimus (substance)	Is a	Calcineurin inhibitor	true	Inferred relationship	Some
Tacrolimus (substance)	Is a	Macrolide immunosuppressant	false	Inferred relationship	Some
Tacrolimus (substance)	Has disposition (attribute)	Calcineurin inhibitor (disposition)	true	Inferred relationship	Some
Tacrolimus (substance)	Is a	Macrolide (substance)	true	Inferred relationship	Some
Tacrolimus (substance)	Is a	Chemical categorized functionally	false	Inferred relationship	Some
Tacrolimus (substance)	Has disposition (attribute)	Immunomodulator (disposition)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing tacrolimus (medicinal product)	Has active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule (clinical drug)	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 5 mg oral capsule	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 5mg/mL infusion concentrate 1mL ampule	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Product containing precisely tacrolimus 500 microgram/1 each conventional release oral capsule (clinical drug)	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 5mg/mL injection	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 0.03% ointment	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus [skin]	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus monohydrate 0.03% ointment	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus monohydrate 0.1% ointment	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Product containing tacrolimus in topical dosage form	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus-containing product in oral dose form	Has active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing tacrolimus in parenteral dose form (medicinal product form)	Has active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 5mg/mL injection solution 1mL vial	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 5mg/1mL infusion concentrate	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Product containing precisely tacrolimus (as tacrolimus monohydrate) 300 microgram/1 gram conventional release cutaneous ointment	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Product containing precisely tacrolimus (as tacrolimus monohydrate) 1 milligram/1 gram conventional release cutaneous ointment	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 0.1% ointment	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 5mg/mL infusion concentrate 1mL ampule	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 5mg/1mL infusion concentrate	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Product containing precisely tacrolimus (as tacrolimus monohydrate) 300 microgram/1 gram conventional release cutaneous ointment	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Product containing precisely tacrolimus (as tacrolimus monohydrate) 1 milligram/1 gram conventional release cutaneous ointment	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Blood tacrolimus level (procedure)	Component	False	Tacrolimus (substance)	Inferred relationship	Some	2
Serum tacrolimus measurement	Component	False	Tacrolimus (substance)	Inferred relationship	Some	2
Tacrolimus measurement	Component	True	Tacrolimus (substance)	Inferred relationship	Some	1
Nephropathy induced by tacrolimus	Causative agent	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 750microgram modified-release tablet	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 4mg modified-release tablet	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 1mg modified-release tablet	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus therapy (procedure)	Direct substance	True	Tacrolimus (substance)	Inferred relationship	Some	2
Tacrolimus monohydrate (substance)	Is a	False	Tacrolimus (substance)	Inferred relationship	Some
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule (clinical drug)	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 5 mg oral capsule	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 5 mg oral capsule	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 500 microgram/1 each conventional release oral capsule (clinical drug)	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 500 microgram/1 each conventional release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 4mg prolonged-release oral tablet	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 1mg prolonged-release oral tablet	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus 750microgram prolonged-release orale tablet	Has active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some
Product containing precisely tacrolimus 1 milligram/1 each conventional release oral capsule (clinical drug)	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 5 mg oral capsule	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 500 microgram/1 each conventional release oral capsule (clinical drug)	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus (as tacrolimus monohydrate) 1 milligram/1 gram conventional release cutaneous ointment	Has basis of strength substance (attribute)	False	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus (as tacrolimus monohydrate) 300 microgram/1 gram conventional release cutaneous ointment	Has basis of strength substance (attribute)	False	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion ampule	Has precise active ingredient	False	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for infusion ampule	Has basis of strength substance (attribute)	False	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus monohydrate (substance)	Is modification of (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some
Tacrolimus-containing product in cutaneous dose form	Has active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing only tacrolimus (medicinal product)	Has active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus only product in cutaneous dose form	Has active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus only product in oral dose form	Has active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing only tacrolimus in parenteral dose form (medicinal product form)	Has active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 5 mg/mL solution for infusion	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 5 mg/mL solution for infusion	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 5 milligram/1 milliliter conventional release solution for injection (clinical drug)	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 300 microgram/1 gram conventional release cutaneous ointment (clinical drug)	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 300 microgram/1 gram conventional release cutaneous ointment (clinical drug)	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 1 milligram/1 gram conventional release cutaneous ointment (clinical drug)	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 1 milligram/1 gram conventional release cutaneous ointment (clinical drug)	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 1 milligram/1 sachet granules for conventional release oral suspension (clinical drug)	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 1 milligram/1 sachet granules for conventional release oral suspension (clinical drug)	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 200 microgram granules for oral suspension sachet	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 200 microgram granules for oral suspension sachet	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 5 mg prolonged-release oral capsule	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 5 mg prolonged-release oral capsule	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 4 mg prolonged-release oral tablet	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 4 mg prolonged-release oral tablet	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 3 milligram/1 each prolonged-release oral capsule (clinical drug)	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 3 milligram/1 each prolonged-release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral tablet (clinical drug)	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral tablet (clinical drug)	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 750 microgram prolonged-release oral tablet	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 750 microgram prolonged-release oral tablet	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 500 microgram prolonged-release oral capsule	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 500 microgram prolonged-release oral capsule	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral capsule (clinical drug)	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Product containing precisely tacrolimus 1 milligram/1 each prolonged-release oral capsule (clinical drug)	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 5 mg/mL solution for infusion and/or injection	Has precise active ingredient	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus 5 mg/mL solution for infusion and/or injection	Has basis of strength substance (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some	1
Tacrolimus anhydrous (substance)	Is modification of (attribute)	True	Tacrolimus (substance)	Inferred relationship	Some
Blood tacrolimus level (procedure)	Component	True	Tacrolimus (substance)	Inferred relationship	Some	1
Serum tacrolimus measurement	Component	True	Tacrolimus (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
1461153017	Tacrolimus (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1481089015	Tacrolimus	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4911401000146115	tacrolimus	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4911411000146118	tacrolimus (substantie)	nl	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)