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37411004: weefselplasminogeenactivator (substantie)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme activator\Tissue plasminogen activator
\Substance categorized by disposition\Enzyme\Hydrolase\Peptide hydrolase\Tissue plasminogen activator

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide (substance)\Protein\Tissue plasminogen activator

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide (substance)\Protein\Tissue plasminogen activator

\Biological substance\Polypeptide (substance)\Protein\Tissue plasminogen activator

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tissue plasminogen activator	Is a	Plasminogen activator	false	Inferred relationship	Some
Tissue plasminogen activator	Is a	Hydrolase	false	Inferred relationship	Some
Tissue plasminogen activator	Has disposition (attribute)	Hydrolase (disposition)	false	Inferred relationship	Some
Tissue plasminogen activator	Has disposition (attribute)	Plasminogen activator (disposition)	true	Inferred relationship	Some
Tissue plasminogen activator	Is a	Enzyme activator	true	Inferred relationship	Some
Tissue plasminogen activator	Is a	Substance with protease mechanism of action	false	Inferred relationship	Some
Tissue plasminogen activator	Is a	Protein	true	Inferred relationship	Some
Tissue plasminogen activator	Is a	Peptide hydrolase	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
tPA-PAI complex assay	Has measured component	False	Tissue plasminogen activator	Inferred relationship	Some
Tissue plasminogen activator assay	Has measured component	False	Tissue plasminogen activator	Inferred relationship	Some
Tissue plasminogen activator activity assay	Has measured component	False	Tissue plasminogen activator	Inferred relationship	Some
Tissue plasminogen activator antigen assay	Has measured component	False	Tissue plasminogen activator	Inferred relationship	Some
Tissue plasminogen activator antigen	Direct substance	False	Tissue plasminogen activator	Inferred relationship	Some
tPA-PAI complex assay	Component	False	Tissue plasminogen activator	Inferred relationship	Some	2
Tissue plasminogen activator assay	Component	True	Tissue plasminogen activator	Inferred relationship	Some	1
Tissue plasminogen activator activity assay	Component	True	Tissue plasminogen activator	Inferred relationship	Some	1
Tissue plasminogen activator antigen assay	Component	True	Tissue plasminogen activator	Inferred relationship	Some	1
Reteplase (substance)	Is a	False	Tissue plasminogen activator	Inferred relationship	Some
Alteplase (substance)	Is a	False	Tissue plasminogen activator	Inferred relationship	Some
Tenecteplase (substance)	Is a	False	Tissue plasminogen activator	Inferred relationship	Some
Product containing tissue plasminogen activator (medicinal product)	Has active ingredient	True	Tissue plasminogen activator	Inferred relationship	Some	1
Product containing reteplase (medicinal product)	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Alteplase 50mg powder and solvent for injection solution vial	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Alteplase 20mg powder and solvent for injection solution vial	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Alteplase 10mg powder and solvent for injection solution vial	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Reteplase 10units powder and solvent for injection solution vial	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Product containing tenecteplase (medicinal product)	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Product containing alteplase (medicinal product)	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Tenecteplase 8000iu(40mg) powder and solvent for injection solution vial	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Tenecteplase 10,000iu(50mg) inj (pdr for recon)+solvent	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Alteplase 1mg injection solution 1mL vial	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Reteplase, recombinant 10unt/vial powder	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Alteplase 100mg powder	Has active ingredient	False	Tissue plasminogen activator	Inferred relationship	Some
Product containing only tissue plasminogen activator (medicinal product)	Has active ingredient	True	Tissue plasminogen activator	Inferred relationship	Some	1
Fibrinolytic disorder caused by tissue plasminogen activator	Causative agent	True	Tissue plasminogen activator	Inferred relationship	Some	2
Intravenous injection of tissue plasminogen activator (procedure)	Direct substance	True	Tissue plasminogen activator	Inferred relationship	Some	1
Intra-arterial injection of tissue plasminogen activator	Direct substance	True	Tissue plasminogen activator	Inferred relationship	Some	1
Adverse reaction caused by tissue plasminogen activator (disorder)	Causative agent	True	Tissue plasminogen activator	Inferred relationship	Some	1
tPA-PAI complex assay	Component	True	Tissue plasminogen activator	Inferred relationship	Some	1

Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
62404015	Tissue plasminogen activator	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
62405019	T-PA	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
769275011	Tissue plasminogen activator (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
14089971000146110	weefselplasminogeenactivator	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
14089981000146112	TPA	nl	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
14089991000146114	tissue plasminogen activator	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
14090001000146113	t-PA	nl	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
14090011000146110	weefselplasminogeenactivator (substantie)	nl	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)