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373526007: cytostaticum (substantie)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with etiopathic disposition mechanism of action (substance)\Cytotoxic

\Drug or medicament (substance)\Antineoplastic agent (substance)\Cytotoxic

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Cytotoxic	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some
Cytotoxic	Has disposition (attribute)	Cytotoxic (disposition)	true	Inferred relationship	Some
Cytotoxic	Is a	Substance categorized by disposition	false	Inferred relationship	Some
Cytotoxic	Is a	Substance with etiopathic disposition mechanism of action (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Denileukin diftitox (substance)	Is a	False	Cytotoxic	Inferred relationship	Some
Product containing temozolomide (medicinal product)	Has active ingredient	False	Cytotoxic	Inferred relationship	Some
Cytotoxic cerebral oedema	Causative agent	False	Cytotoxic	Inferred relationship	Some	2
Chemotherapy sickness	Causative agent	False	Cytotoxic	Inferred relationship	Some
Post-chemotherapy testicular hypofunction	Causative agent	False	Cytotoxic	Inferred relationship	Some
Cytotoxic drug-induced hypospermatogenesis	Causative agent	False	Cytotoxic	Inferred relationship	Some
Congenital malformation caused by cytotoxic agents (disorder)	Causative agent	False	Cytotoxic	Inferred relationship	Some
Cytotoxic superficial application	Direct substance	False	Cytotoxic	Inferred relationship	Some	1
Product containing precisely temozolomide 5 milligram/1 each conventional release oral capsule (clinical drug)	Has active ingredient	False	Cytotoxic	Inferred relationship	Some
Temozolomide 20 mg oral capsule	Has active ingredient	False	Cytotoxic	Inferred relationship	Some
Temozolomide 100 mg oral capsule	Has active ingredient	False	Cytotoxic	Inferred relationship	Some
Temozolomide 250 mg oral capsule	Has active ingredient	False	Cytotoxic	Inferred relationship	Some
Fetal aminopterin syndrome	Causative agent	False	Cytotoxic	Inferred relationship	Some
Cytotoxic agent	Has active ingredient	False	Cytotoxic	Inferred relationship	Some
Temozolomide (substance)	Is a	True	Cytotoxic	Inferred relationship	Some
Altretamine (substance)	Is a	False	Cytotoxic	Inferred relationship	Some
Cytotoxic drug therapy NOS	Direct substance	False	Cytotoxic	Inferred relationship	Some
Synthetic cytotoxic triazine derivative	Is a	False	Cytotoxic	Inferred relationship	Some
Recombinant interleukin 2 moiety	Is a	False	Cytotoxic	Inferred relationship	Some
Introduction of cytotoxic substance into pleural cavity	Direct substance	False	Cytotoxic	Inferred relationship	Some	1
Intraperitoneal administration of cytotoxic drug	Direct substance	False	Cytotoxic	Inferred relationship	Some	1
Injection of cytotoxic substance into artery of head (procedure)	Direct substance	False	Cytotoxic	Inferred relationship	Some	1
Cytotoxic given orally	Direct substance	False	Cytotoxic	Inferred relationship	Some	1
Cytotoxic superficial application	Direct substance	True	Cytotoxic	Inferred relationship	Some	1
Intraperitoneal administration of cytotoxic drug	Direct substance	False	Cytotoxic	Inferred relationship	Some	1
Cytotoxic given orally	Direct substance	False	Cytotoxic	Inferred relationship	Some	1
Injection of cytotoxic substance into artery of head (procedure)	Direct substance	True	Cytotoxic	Inferred relationship	Some	1
Intraperitoneal administration of cytotoxic drug	Direct substance	True	Cytotoxic	Inferred relationship	Some	1
Introduction of cytotoxic substance into pleural cavity	Direct substance	True	Cytotoxic	Inferred relationship	Some	1
Dermatosis due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Syringosquamous metaplasia due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Cutaneous inflammation due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Stomatitis due to cytotoxic therapy (disorder)	Causative agent	False	Cytotoxic	Inferred relationship	Some	3
Acral erythema due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Pseudoscleroderma due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Methotrexate skin ulceration (disorder)	Causative agent	False	Cytotoxic	Inferred relationship	Some
Cutaneous ulceration due to cytotoxic therapy (disorder)	Causative agent	False	Cytotoxic	Inferred relationship	Some
Nail dystrophy due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Neutrophilic eccrine hidradenitis due to cytotoxic therapy (disorder)	Causative agent	False	Cytotoxic	Inferred relationship	Some	1
Ultraviolet recall reaction due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Radiation recall reaction due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Administration of cytotoxic agent via oral route (procedure)	Direct substance	True	Cytotoxic	Inferred relationship	Some	1
Cytotoxic drug-induced hypospermatogenesis	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Cutaneous ulceration due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Stomatitis due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Neutrophilic eccrine hidradenitis due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	2
Acral erythema due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	2
Cytotoxic cerebral oedema	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Recombinant interleukin 2	Is a	True	Cytotoxic	Inferred relationship	Some
Congenital malformation caused by cytotoxic agents (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	1
Neutrophilic eccrine hidradenitis due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	5
Neutrophilic eccrine hidradenitis due to cytotoxic therapy (disorder)	Causative agent	True	Cytotoxic	Inferred relationship	Some	3

Reference Sets

Dutch pathology simple reference set (foundation metadata concept)

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Id	Description	Lang	Type	Status	Case?	Module
3520634014	Cytotoxic	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3520724014	Cytotoxic (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4526921000146113	cytostaticum	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4526931000146110	oncolyticum	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4526941000146119	oncostaticum	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4526951000146116	cytostaticum (substantie)	nl	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4526961000146118	carcinolyticum	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4526971000146112	carcinostaticum	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
4526981000146114	cytotoxicum	nl	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)
13085901000146119	Medicijnen die de celdeling remmen en gebruikt worden bij kankertherapie.	nl	Definition	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Netherlands NRC maintained module (core metadata concept)